Clinical trials: CAN
Healthy
VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?
This is a single-center, randomized, partially blinded study to determine whether 42-day old red blood cells (RBCs) deliver oxygen as effectively as 7-day old RBCs and also to determine whether transfusion with 28-day old RBCs is…
- Trial name
- NCT02918851
- Testing
- Transfusion of 7-day stored red blood cells, Transfusion of 28-day stored red blood cells, Transfusion of 42-day stored red blood cells
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetes Mellitus, Type 2
Can Exenatide Prevent Increase in EGP in Response to Dapagliflozin-induced Increase in Glucosuria
Research Design/Plan: After screening, each subject will receive 1 measurements of Endogenous Glucose Production [EGP] with prime-continuous Infusion of 3-3H-glucose.
- Trial name
- NCT03331289
- Testing
- Exenatide, Dapagliflozin, Exenatide and Dapagliflozin
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hyperlipidemia, Diabetes
Point-of-Care Testing (POCT) Detection and Management of Metabolic Syndrome in Patients With Mental Illness
The study was a 12-month, multi-centered, quasi-experimental design to assess point-of-care (POCT) screening/monitoring of subjects on antipsychotic agents for metabolic syndrome.
- Conditions
- Hyperlipidemia, Diabetes, Hypertension
- Trial name
- NCT02029989
- Testing
- Glucose and lipids, Glycosylated Hemoglobin A1c, Blood Pressure and Heart Rate
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Post Traumatic Stress Disorders
Can Service Dogs Improve Activity and Quality of Life in Veterans With PTSD?
Service Dogs are trained to assist people with disabilities to accomplish tasks which permit the individual to be more functional in their home and social environment.
- Trial name
- SDPTSD (NCT02039843)
- Testing
- Emotional Support Dogs, Service Dogs
- Where
- 4 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Contraception
E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada Study
The objectives of this study are to evaluate the contraceptive efficacy, vaginal bleeding pattern (cycle control), and the general safety and acceptability of the 15 mg estetrol (E4)/3 mg drospirenone (DRSP) combination in…
- Trial name
- NCT02817841
- Testing
- 15 mg E4/3 mg DRSP
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,148 people, healthy volunteers welcome
- Sponsor
- Estetra
Dry Eye
Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?
Can Lyrica (Pregabalin) help prevent severe Dry Eye post LASIK surgery?
- Trial name
- NCT02701764
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Miami
Female Pelvic Exam
Preparing Medical Students to Undertake a First Female Pelvic Exam.
Objective: To evaluate the effectiveness of a web based learning module in the preparation of medical students to undertake a first female pelvic exam.
- Trial name
- NCT01101971
- Testing
- Pelvic exam video tutorial
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Queen's University
Frailty, Sedentary Behavior
Stand if You Can: A Standing Intervention in Long Term Care
It is currently unknown if reducing sitting time, an activity that is highly prevalent in frail older adults living in long term care (LTC) facilities, is associated with an improvement in physical capacity such as walking speed.
- Conditions
- Frailty, Sedentary Behavior, Physical Disability
- Trial name
- NCT03796039
- Testing
- Standing
- Where
- Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Traumatic Brain Injury
Test of Chamber Pressure to Divers and Chamber Attendants
SCUBA divers and chamber inside attendants will undergo a brief hyperbaric chamber excursion and will be asked to what chamber pressure they were compressed and what gas they breathed.
- Trial name
- TOP-DIVER (NCT01430325)
- Testing
- Hyperbaric Oxygen (1.5 atm abs)
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Procedural Anxiety, Procedural Pain
Can Virtual Reality Reduce Pain and Anxiety During Blood Draw
Adult patients aged 18-50 undergoing blood draw for routine lab evaluation will be randomized to a control group or experimental group to assess if the use of virtual reality reduces procedural pain (primary outcome) and…
- Trial name
- NCT04449341
- Testing
- Oculus Go headset with Ocean Rift application
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- C.R.Darnall Army Medical Center
Pregnancy Complications, Cesarean Section
Outcomes of Cesarean Section vs Vaginal Delivery: Instrumental Variable Adjusted Analysis
This study will examine the effect of cesarean section on perinatal mortality, using data provided by the Canadian Institute for Health Information.
- Trial name
- NCT02866058
- Testing
- Cesarean Section
- Volunteers
- 836,755 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Infant Mortality, BCG
Can Earlier BCG Vaccination Reduce Early Infant Mortality? A Randomised Trial
The purpose of this study is to determine whether BCG vaccination shortly after birth can reduce early infant mortality in a rural and an urban setting.
- Trial name
- BCGR (NCT02504203)
- Testing
- BCG-Denmark 1331 (Statens Serum Institute)
- Where
- Guinea-Bissau
- Volunteers
- 2,332 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Massage Therapy, Health-care Workers
Can Massage During One Year Improve Health in Health-care Providers Working in Hospital
The overall aim of this pilot study is to investigate the effect, "feasibility" and experiences of regular massage over 12 months on the mental and physical health of healthcare professionals, as well as the frequency of layoffs…
- Conditions
- Massage Therapy, Health-care Workers, Quality of Life, Psychological Distress
- Trial name
- NCT05555082
- Testing
- Massage
- Where
- 2 sites in Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Upper Respiratory Tract Infections
Nasal Spray With Glucose Oxidase Preventing Common Cold in Pre-school Children
To investigate if use of glucosoxidas nasal spray can reduce the number of days with upper respiratory tract infections in children beyond 4 years.
- Trial name
- NCT01883427
- Testing
- Glucose oxidase
- Where
- 4 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Krister Tano
Type 1 Diabetes
Obtain a Good Blood Glucose Control With the Paradigm Real Time System
In this study, subjects with insufficient metabolic control despite optimized basal-bolus injection regimens were randomily assigned to either the Mini- Med Paradigm REAL-Time insulin pump (PRT), an insulin pump that can receive…
- Trial name
- RTD (NCT00441129)
- Testing
- Minimed paradigm Real Time Sytem, Minimed Paradigm 512/712 Insulin pump
- Where
- 8 sites in France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Medtronic MiniMed, Inc.
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Cardiovascular Diseases
Cardiovascular Disease Population Risk Tool
The purpose of this study is to develop, evaluate, and apply a predictive algorithm for assessing CVD risk in the community setting: the Cardiovascular Disease Population Risk Tool (CVDPoRT).
- Trial name
- CVDPoRT (NCT02267447)
- Volunteers
- 104,219 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
HIV Testing, HIV Infections
OraQuick® HIV Self-Test Study in Canada
Oral fluid based HIV Self-testing (HIVST) provides another innovative and simple option to increase opportunities for HIV testing.
- Trial name
- OQHIVST (NCT05020353)
- Testing
- OraQuick® HIV Self-Test
- Where
- 7 sites in Canada
- Volunteers
- 951 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Developmental Delay
The CHICA Developmental Screening Study
The aims of this study are to (1) Expand and modify an existing computer-based decision support system (CHICA) to include the 2006 AAP developmental surveillance and screening algorithm; (2) Evaluate the effect of the CHICA…
- Trial name
- NCT01351077
- Testing
- CHICA DevScreen Module
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Indiana University