Clinical trials: CAR
Autism Spectrum Disorder, Autistic Disorder
Risk Factors and Prognosis of Autism Spectrum Disorder
This case-control study with prospective follow-up aims to identify risk factors associated with autism spectrum disorder and to evaluate the prognosis of children with ASD attending Assiut University Children's Hospital.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Child Development Disorders, Pervasive
- Trial name
- NCT07818460
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Child Safety Seat Harness Tension
Minnesota HealthSolutions Cellular Car Seat Study
The objective of the study is to evaluate an innovative child safety seat user engagement system (CCS system) designed to actively educate, instruct, and alarm caregivers with information associated with automatically-sensed…
- Trial name
- NCT05552027
- Testing
- CCS System- Prototype, CCS System- Control
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Children, Mobility Limitation
Parental Perspectives of Using Toy Cars on Social Interactions of Preschool Children With Mobility Impairments
The purpose of this study is to investigate parental attitudes towards their child who has a mobility impairment, to using a modified electric toy car, and to evaluate from their perspective, if it facilitated social interaction…
- Conditions
- Children, Mobility Limitation, Spina Bifida, Attitude to Health
- Trial name
- NCT02682043
- Testing
- Toy car
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Traffic Collision, Transport Accident
Causes of Traffic Collisions of Ambulance Cars at the Prague Emergency Medical Services
The aim of the project is to increase the protection of patients, employees and the organization by means of data collection about traffic collisions of ambulance cars.
- Trial name
- NCT04808219
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Peran
Multiple Myeloma
Efficacy and Safety Evaluation of BCMA-UCART
This trial aims to evaluate the safety and efficacy of BCMA-UCART in treating patients with relapsed or refractory multiple myeloma.
- Trial name
- NCT03752541
- Testing
- BCMA-UCART
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bioray Laboratories
Carotid Artery Diseases, Healthy Volunteers
Multicenter Normal Reference Study of Carotid Artery Ultrafast Pulse Wave Velocity (UFPWV)
To establish the range of BS and ES (m/s) of normal carotid artery by using ultrafast pulse wave velocity (UFPWV), and to explore the influencing factors.
- Trial name
- NCT03351127
- Testing
- Carotid ultrasound examination
- Where
- 44 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Injury
Preventing Motor Vehicle Crashes Among Young Drivers: Evaluation of the Checkpoints Program Presented by the American Automobile Association
Background: Automobile crash risks are highest right after licensure and decline rapidly for about 6 months and then gradually for years, regardless of the amount of supervised practice driving or age at licensure.
- Trial name
- NCT00920049
- Testing
- Persuasion
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Automobile Driving
Development of a Valid Test Battery for Assessing Driving Ability When Influenced by Drugs.
The purpose of the validation study is to develop a valid test battery for assessing driving ability in a driving simulator when influenced by drugs.
- Trial name
- VALIDAD (NCT00967421)
- Testing
- ethanol
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia
Ride-On Toy Car Use During Operating Room Transfer in Preschool Children
The goal of this clinical trial is to determine whether the method of transfer to the operating room can reduce preoperative anxiety and postoperative emergence delirium in male children aged 3 to 7 years undergoing elective…
- Trial name
- NCT07403747
- Testing
- Toy car, Standard Transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Diffuse Large B Cell Lymphoma
Is Trogocytosis a Predictive Marker of CAR-T Cell Response in Diffuse Large B-cell Lymphoma?
CAR-T cell therapy has improved survival in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL R/R). However, only 65% of patients achieve a complete metabolic response after this treatment.
- Trial name
- CARTROG (NCT06352242)
- Testing
- Flow cytometry analysis to determine the level of trogocytosis by effector immune cells in patients, Flow cytometry analysis to determine the level of trogocytosis by effector immune cells in volunteers
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Homonymous Hemianopia
Assessment of Homonymous Visual Loss and Its Impact on Visual Exploration, Activities of Daily Living (ADL) and Quality of Life (QoL)
The purpose of this explorative study, targeting subjects with homonymous visual field loss, is threefold: (i) to identify the perimetric / psychophysical method, that is most closely correlated with an individually assessed…
- Trial name
- Hemi-Drive (NCT01372332)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Non Small Cell Lung Cancer
Study of CXCR5 Modified EGFR Targeted CAR-T Cells for Advanced NSCLC
This study is a single arm, open-label, intravenous infusion of Anti- Epidermal growth factor receptor (EGFR) Chimeric Antigen Receptor (CAR) T cells modified by C-X-C Chemokine receptor type 5 (CXCR 5) in patients with advanced…
- Trial name
- NCT05060796
- Testing
- CXCR5 modified EGFR Chimeric Antigen Receptor Autologous T cells
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Automobile Driving, Active Commuting
InterMob: a Randomized Controlled Trial Aimed at Reducing Car Use in Regular Car Users
Regular car use is a source of pollution and physical inactivity. InterMob is an interdisciplinary randomized controlled behavioral intervention aiming at reducing car use.
- Trial name
- InterMob (NCT05096000)
- Testing
- InterMob: a randomized controlled trial aimed at reducing car use in regular car users, Active control: Air pollution information
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Aina Chalabaev
Leukemia
Production of Clinical-grade Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory B-cell Malignancies
Immunotherapy is a promising therapeutic approach for patients with cancers. Patients with acute lymphoblastic leukemia (ALL) experiencing early relapse less than 18 months from diagnosis had very poor prognosis with 5-year…
- Trial name
- NCT03624686
- Testing
- peripheral blood
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Automobile Driving
Driving Ability Evaluation System to Improve the Conditional Driving License System: Safety and Feasibility Study.
The primary objective of this study is to verify the safety and validity of a VR driving simulator developed for evaluating the driving abilities in healthy adults.
- Trial name
- NCT06279520
- Testing
- VR Driving Simulator, Computerized Neurocognitive Function Test, Driver Test Station
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Child Passenger Safety
Video-Based Social Learning or Didactics for Car Seat Education
This study compares a video-based social learning method to the traditional didactic method as a new way to teach caregivers about child passenger safety, including how to install a car seat.
- Trial name
- NCT02720289
- Testing
- Video-based social learning class, Traditional didactic class
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Prevention Harmful Effects, Accidents, Traffic
Comparing Driving Performance Among Trained and Untrained Drivers Using a Driving Simulator
The purpose of this study is to examine differences in driving performance on a simulated driving assessment between novice teen drivers who receive the Risk Anticipation-Perception Training (RAPT) program and novice teen drivers…
- Conditions
- Prevention Harmful Effects, Accidents, Traffic, Accident Prevention
- Trial name
- NCT01619202
- Testing
- Risk Anticipation -Perception Training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Accidents, Traffic, Whiplash Injuries
The Analysis for Termination of Treatment and Satisfaction in Traffic Accident Patient
Data of one hospital will be used to find out the patient's satisfaction with the treatment, analyze the factors effecting on the treatment termination.
- Trial name
- NCT04167930
- Testing
- electronic medical record(EMR) Data and patient survey
- Where
- 2 sites in South Korea
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation
Leukemia, Hematopoetic Stem Cell Transplantation
Exercise as an Immune Adjuvant for Allogeneic Cell Therapies
This study aims to improve the treatment of blood cancer by using exercise to collect healthier immune cells from donors. Allogeneic adoptive cell therapy is a treatment where immune cells from a healthy donor are given to a…
- Conditions
- Leukemia, Hematopoetic Stem Cell Transplantation, Donor Lymphocyte Infusion, CAR T-Cell Therapy
- Trial name
- Allo-X (NCT06643221)
- Testing
- Exercise, Isoproterenol, Bisoprolol Fumarate Tablet 10 mg
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arizona