Clinical trials: CAS
Carotid Artery Disease
CAPITAL: Carotid Artery Plaque Intravascular Ultrasound Evaluation
To assess the safety and feasibility of Volcano Corp Eagle Eye Gold Catheter system to correlate the presence and characteristic of carotid artery atherosclerotic disease with anatomic and histologic analysis.
- Trial name
- NCT00271076
- Testing
- IVUS, CAS, CEA
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Arizona Heart Institute
Carotid Stenosis
Determination of the Best Therapeutic Strategy, Interventional With Best Medical Management (BMM) Versus BMM Alone, for Patients With Symptomatic Moderate <70% Atherosclerotic Carotid Artery Stenosis: the SIMCA Multicenter Randomized Trial
Stroke is one of the leading causes of death and the main cause of long-term disability worldwide. A frequent cause is the narrowing of the carotid artery due to atherosclerosis, known as carotid artery stenosis.
- Trial name
- SIMCA (NCT07839390)
- Testing
- endarterectomy, stenting, Control group
- Volunteers
- 1,440 people
- Sponsor
- Central Hospital, Nancy, France
Vitamin D Deficiency
Vitamin D Intervention Trial in Healthy Chinese, Phase II
This is a double-blind, randomized, placebo-controlled trial. Based on inclusion and exclusion criteria, 400 eligible volunteers, who were 20-45 years, with 25-hydroxyvitamin D between 12.5-50 nmol/L and BMI between 18.5-28…
- Trial name
- NCT01998763
- Testing
- Vitamin D3
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Knee Arthroplasty, Total
CAS vs Standard Technique in TKA: Comparison of Clinical and Functional Results
The study involves the enrollment of a sample of patients with indication for total knee replacement surgery in order to compare the conventional surgical technique currently used in the reference departments with the surgical…
- Trial name
- CAS-K (NCT06608745)
- Testing
- conventional total knee arthroplasty, computer-assisted total knee arthroplasty
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Istituto Ortopedico Rizzoli
Alzheimer Disease
Eye to Brain Connection
This is a non-randomized, non-treatment, observational study designed to discover correlations between retinal imaging and amyloid PET imaging. Subjects will be recruited to the clinical cohort from referring physicians.
- Trial name
- NCT05215782
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Optina Diagnostics Inc.
Childhood Apraxia of Speech
Methylphenidate in Childhood Apraxia of Speech
The purpose of this study is to describe the possible effects of methylphenidate (MPH) on speech intelligibility in children with childhood apraxia of speech (CAS) aged 6-12 years.
- Trial name
- NCT05185583
- Testing
- Methylphenidate Hydrochloride
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- Murdoch Childrens Research Institute
Stroke
Inter-Tester Reliability Of the Cumulated Ambulation Score in Patients With Stroke (InTRO-CAS-stroke)
CAS is a measurement of basic mobility describing the degree of independence in three activities; getting in and out of bed, sit-to-stand from a chair with armrests, and indoor walking - each assessed on a three-point ordinal…
- Trial name
- NCT05601089
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Childhood Apraxia of Speech
Dose Frequency RCT on DTTC in Children With CAS
Childhood apraxia of speech (CAS) is a pediatric motor-based speech sound disorder that requires a specialized approach to intervention (Maas et al., 2014).
- Trial name
- NCT05675306
- Testing
- Dynamic Temporal and Tactile Cueing Treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marquette University
Childhood Apraxia of Speech, Verbal Apraxia
Role of Omega-DEK in Childhood Apraxia of Speech
This is a 20-week study for children between 3 and 6 years old with confirmed childhood apraxia of speech (CAS). The study includes a 12-week open-label pilot feasibility study of an investigational drug (Omega-DEK) plus…
- Conditions
- Childhood Apraxia of Speech, Verbal Apraxia, Autism
- Trial name
- NCT07216001
- Testing
- Omega-DEK, L-carnitine
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Claudia R. Morris
Carotid Artery Stenosis
PROximal Protection VErsus NON-Protection in Carotid Artery Stenting
To compare the incidence of new ischemic brain injury detected with magnetic resonance imaging (MRI) after carotid artery stenting in patients treated with and without proximal cerebral protection (Gore Flow Reversal System).
- Trial name
- PROVENON (NCT01331473)
- Testing
- Carotid Artery Stenting with Proximal Protection, Carotid Artery Stenting without Protection
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Universität des Saarlandes
Twin to Twin Transfusion
The Effect of Uterine Entry In Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of…
- Trial name
- NCT06829901
- Testing
- Fetoscopic Laser Photocoagulation
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Baylor College of Medicine
Osteoarthritis
Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated Study
The primary objective of this investigation is to compare the precision of long leg alignment achieved by the two types of procedure.
- Trial name
- NCT00733330
- Testing
- Either P.F.C. Sigma or L.C.S. Complete knee replacement using the conventional surgical approach and manual surgical technique, Either P.F.C. Sigma or L.C.S. Complete knee replacement using minimally invasive surgical approach and computer navigation
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 86 people
- Sponsor
- DePuy International
Children
Children's Aid Societies: Differential Response and Wraparound Prevention Trial
The purpose of this study is to assess the cost-effectiveness of this Differential Wraparound model, in 5 Children's Aid Societies within Hamilton-Niagara Region, in preventing maltreatment cases from either becoming ongoing…
- Trial name
- NCT00559208
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- Hamilton Children's Aid Society
Cardiogenic Shock
Polish Nationwide Registry of Diagnostics, Treatment and Outcome in Patients With Cardiogenic Shock
The registry objective is to get information on current epidemiology, diagnostics, treatment and outcome in patients with cardiogenic shock in Poland.
- Trial name
- CaS-POL (NCT06697093)
- Where
- 2 sites in Poland
- Volunteers
- 500 people
- Sponsor
- Wroclaw Medical University
COVID-19 Pandemic
Analysing the Psychosocial Effects of COVID-19 Pandemic on Dental Professionals Using the Turkish Version of the Fear of COVID-19 and Coronavirus Anxiety Scales
The aims of this study were to (i) assess fear and anxiety of COVID-19 in a Turkish sample dental professionals using the Turkish FCV-19S and CAS; (ii) explore factors associated with FCV-19S and CAS; and (iii) examine the…
- Trial name
- NCT04674644
- Testing
- The psychosocial effects of COVID-19 pandemic on dental professionals
- Where
- Turkey (Türkiye)
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Childhood Apraxia of Speech
Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children
This study will investigate the feasibility of applying the Rapid Syllable Transition Treatment (ReST) protocol in children with Childhood Apraxia of Speech, considering the scarcity of evidence in the context of Brazilian…
- Trial name
- ReST-SSD (NCT07636031)
- Testing
- Rapid Syllable Transition Treatment (ReST)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Aline Mara de Oliveira
Advanced Hepatocellular Carcinoma
TACE Combined With PD-1 Knockout Engineered T Cell in Advanced Hepatocellular Carcinoma.
This study will evaluate the safety and effect of transcatheter arterial chemoembolization (TACE)combined with percutaneous transhepatic PD-1 knockout engineered T cell infusion in the Paitents with advanced hepatocellular…
- Trial name
- NCT04417764
- Testing
- Transcatheter arterial chemoembolization, PD-1 knockout engineered T cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Central South University
Emotional Resilience
A Network Analysis on the Role of Specific ER Abilities as ERFs for Distress and Mental Health, in Relation to CAs Exposure in the AYAs
This activity will aim to compare the network of emotional resilience factors and stress in adolescents and young adults depending on the childhood abuse exposure (considered moderator), using a network analysis approach.
- Trial name
- NCT06986928
- Testing
- No intervention will be applied.
- Where
- Romania
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Childhood Apraxia of Speech
The Effects of Caregiver Training on DTTC Treatment Outcomes in CAS
The goal of this clinical trial is to investigate the impact of direct vs. indirect caregiver training on treatment outcomes following a period of Dynamic Temporal and Tactile Cueing (DTTC) intervention combined with home…
- Trial name
- DTTC (NCT05916222)
- Testing
- Dynamic Temporal and Tactile Cueing (DTTC)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- New York University
Childhood Apraxia of Speech
ASSIST: Treatment for Childhood Apraxia of Speech
Childhood apraxia of speech (CAS) is a pediatric motor speech disorder that impairs the planning of movements needed for intelligible speech. Children with CAS often show little or slow progress in standard speech therapy.
- Trial name
- ASSIST (NCT03903120)
- Testing
- ASSIST
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Temple University