Clinical trials: CAS
Carotid Artery Stenosis, Carotid Artery Stenting
CAS for Stenosis With High-risk Features for CEA
The purpose of this prospective, multicenter, single-group target-value study is to evaluate the safety and efficacy of the carotid artery stent system in patients with high-risk features for carotid endarterectomy.
- Trial name
- HeartCare CAS (NCT07370246)
- Testing
- Carotid artery stent system
- Where
- 16 sites in China
- Volunteers
- 212 people
- Sponsor
- Beijing Tiantan Hospital
Coronary Artery Disease, Coronary Stenosis
TARGET-PREMIER Trail in Evaluating the Safety and Efficacy of the Rapamycin Target Eluting Stent in CAS Treatment
The aim of the TARGET PREMIER trail in to demonstrate the safety and efficacy of the rapamycin target eluting stent in the treatment of subjects with ischemic heart disease (asymptomatic myocardial ischemia , table or unstable…
- Trial name
- T-P (NCT04951050)
- Testing
- Rapamycin target eluting stent
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai MicroPort Medical (Group) Co., Ltd.
Carotid Stenosis
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
As with coronary artery stenting, activation and embolisation of platelets occurs with carotid artery stenting (CAS). Based on promising data on the use of clopidogrel plus aspirin in coronary stenting this dual antiplatelet…
- Trial name
- IMPACT (NCT01146301)
- Testing
- Clopidogrel
- Where
- Netherlands
- Sponsor
- R&D Cardiologie
Peripheral Artery Disease, Carotid Artery Stenosis
Study on PAD and CAS Based on Omics and Imaging
This study aims to investigate the pathogenesis of Peripheral Artery Disease (PAD) and Carotid Artery Stenosis (CAS) using a comprehensive multi-omics and multi-modal imaging approach.
- Conditions
- Peripheral Artery Disease, Carotid Artery Stenosis, Artery Stenosis
- Trial name
- NCT06917547
- Volunteers
- 100 people
- Sponsor
- Yijie Ning
Coronary Artery Disease
ENdothelial Healing Assessment With Novel Coronary tEchnology
This is a prospective, non-randomized, single center clinical trial to assess neointimal coverage on the stent or scaffold strut and apposition of SYNERGY™ and ABSORB in minimum of 12 eligible human subject at 4 month and 12…
- Trial name
- ENHANCE (NCT02747199)
- Testing
- SYNERGY stent, BVS ABSORB scaffold
- Volunteers
- 13 people
- Sponsor
- University of Malaya
Generalized Anxiety Disorder
Group vs. Individual Metacognitive Therapy for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a serious and long-lasting condition that can greatly reduce quality of life, work functioning, and use of health services.
- Trial name
- NCT07579897
- Testing
- Individual Metacognitive Therapy, Group Metacognitive Therapy
- Where
- 2 sites in Norway
- Volunteers
- 64 people
- Sponsor
- Sorlandet Hospital HF
Chronic Ankle Sprain, Chronic Ankle Sprains
Investigating the Effects of Cognitive Functional Therapy on Pain, Physical Function, and Kinesiophobia in Individuals With Chronic Ankle Sprain
The aim of this study is to investigate the effects of Cognitive Functional Therapy (CFT) on pain, physical function, and kinesiophobia in individuals with chronic ankle sprain (CAS).
- Trial name
- NCT07449078
- Testing
- Cognitive Functional Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Patients With Osteoarthritis Undergoing CAS-TKA
Effects of Programmed Cryotherapy and Continuous Passive Motion After Computer-Assisted Total Knee Arthroplasty
The hypothesis of this study was the patients, who received programed cryotherapy and CPM, had experienced less postoperative pain, joint swelling, and increased ROM following CAS-TKA.
- Trial name
- NCT04136431
- Testing
- Programed cryotherapy and continuous passive motion, Unrogramed cryotherapy and continuous passive motion
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Alzheimer Disease, Mild Cognitive Impairment
Optina Diagnostics' Cerebral ß-Amyloid Status (CAS) Test
This observational, cross-sectional study is designed to validate a novel diagnostic test for the detection of phenotypic changes in the retina that correlate with likely PET amyloid status (negative or positive), to aid in the…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia
- Trial name
- REPHRASE (NCT05107882)
- Where
- 7 sites in United States, Canada
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Optina Diagnostics Inc.
Children
Children's Aid Societies: Differential Response and Wraparound Prevention Trial
The purpose of this study is to assess the cost-effectiveness of this Differential Wraparound model, in 5 Children's Aid Societies within Hamilton-Niagara Region, in preventing maltreatment cases from either becoming ongoing…
- Trial name
- NCT00559208
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- Hamilton Children's Aid Society
Carotid Artery Disease, Carotid Artery Stenosis
The Gore SCAFFOLD Clinical Study
Evaluate the safety and efficacy of the GORE® Carotid Stent for the treatment of carotid artery stenosis in patients at increased risk for adverse events from carotid endarterectomy
- Trial name
- NCT01901874
- Testing
- Carotid Artery Stenting
- Where
- 2 sites in United States
- Volunteers
- 312 people
- Sponsor
- W.L.Gore & Associates
Carotid Artery Stenosis, Carotid Artery Stenting
Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS
About 20% of stroke causes are atherosclerotic strokes caused by carotid artery stenosis. In 2005, 92% of carotid artery interventions in the USA were performed in asymptomatic patients.
- Conditions
- Carotid Artery Stenosis, Carotid Artery Stenting, Stroke
- Trial name
- NOTICE-CAS (NCT06123767)
- Testing
- CAS + Intravascular measuring the pressure gradient, CAS (standard), Doppler ultrasonound of cephalic arteries
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Femur Fracture
Effect of Preoperative Carbohydrate Loading in Femur Fracture
Femur fracture is very common in older people. It makes the people bedridden for long time at hospital. The fracture of femur is generally managed by the surgical procedure.
- Trial name
- NCT04838366
- Testing
- Carbohydrate loading
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Carotid Artery Stenosis
A Cohort Study Comparing PCSK9 Inhibitor Plus Statin With Statin Monotherapy for Carotid Artery Stenosis
A multicenter cohort study
- Trial name
- TRIP-CAS (NCT07036991)
- Testing
- PCSK9 inhibitor (biweekly injections) + Rosuvastatin/Atorvastatin ± Ezetimibe, Rosuvastatin/Atorvastatin ± Ezetimibe
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Changhai Hospital
Stroke
Inter-Tester Reliability Of the Cumulated Ambulation Score in Patients With Stroke (InTRO-CAS-stroke)
CAS is a measurement of basic mobility describing the degree of independence in three activities; getting in and out of bed, sit-to-stand from a chair with armrests, and indoor walking - each assessed on a three-point ordinal…
- Trial name
- NCT05601089
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Adenocarcinoma of the Uterine Cervix
Adenocarcinoma of the Uterine Cervix and HPV
The present study will mainly aim to review and characterize the pathologic features, treatment options, and follow-up outcomes of women with in situ/microinvasive adenocarcinoma of the uterine cervix according to HPV status…
- Trial name
- NCT05267834
- Testing
- Conization and/or Hysterectomy
- Where
- Italy
- Volunteers
- 148 people
- Sponsor
- Università Politecnica delle Marche
Cold Agglutinin Disease (CAD), Cold Agglutinin Syndrome (CAS)
Cold Agglutinin Disease Real World Evidence Registry
This is a multinational, multi-center, observational, prospective, longitudinal disease registry designed to collect data on participants with cold agglutinin disease (CAD) or cold agglutinin syndrome (CAS).
- Trial name
- CADENCE (NCT05791708)
- Testing
- Sutimlimab
- Where
- 68 sites in United States, Austria and 6 more
- Volunteers
- 429 people
- Sponsor
- RECORDATI GROUP
Primary Dystonia
Contribution of the Cerebellum In Sensory-motor Adaptation Via Gamma Oscillations: the Case of Dystonia
Dystonia, a disabling disease with uncontrolled movement disorders was considered to be a manifestation of basal ganglia dysfunction, yet there is accumulating evidence from animal and human experiments that the cerebellum plays…
- Trial name
- GAMMA (NCT02073630)
- Testing
- active cerebellar stimulation
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Emotional Resilience
A Network Analysis on the Role of Specific ER Abilities as ERFs for Distress and Mental Health, in Relation to CAs Exposure in the AYAs
This activity will aim to compare the network of emotional resilience factors and stress in adolescents and young adults depending on the childhood abuse exposure (considered moderator), using a network analysis approach.
- Trial name
- NCT06986928
- Testing
- No intervention will be applied.
- Where
- Romania
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University