Clinical trials: CAS
Mitral Regurgitation, Mitral Valve Regurgitation
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS
The purpose of the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) Trial is to confirm the safety and effectiveness of the MitraClip…
- Conditions
- Mitral Regurgitation, Mitral Valve Regurgitation, Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects, Heart Failure
- Trial name
- COAPT (NCT01626079)
- Testing
- MitraClip System
- Where
- 86 sites in United States, Canada
- Volunteers
- 776 people
- Sponsor
- Abbott Medical Devices
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Carotid Stenosis, Constriction, Pathologic
GORE Flow Reversal System and GORE Embolic Filter Extension Study
The objective of this study is to provide an ongoing evaluation of clinical outcomes associated with the GORE Flow Reversal System and the GORE Embolic Filter when used for embolic protection during carotid artery stenting.
- Conditions
- Carotid Stenosis, Constriction, Pathologic, Carotid Artery Diseases, Cerebrovascular Disorders
- Trial name
- FREEDOM (NCT01343667)
- Testing
- Gore Flow Reversal System, Gore Embolic Filter
- Where
- 39 sites in United States
- Volunteers
- 1,397 people
- Sponsor
- W.L.Gore & Associates
Valve-in-valve Procedures, Aortic Stenosis
The ShortCut™ Continued Access Study Protocol
A Prospective, Multicenter, Non-Randomized, Single-Arm, Open-Label Continued Access Study of the ShortCut™ device (The ShortCut™ CAS).
- Conditions
- Valve-in-valve Procedures, Aortic Stenosis, Coronary; Obstruction
- Trial name
- ShortCut-CAS (NCT06211296)
- Testing
- Shortcut
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Pi-cardia
Cardiac Catheterization
Validation of Brain Oxygenation Monitor on Pediatric Patients
The aim of this study is calibrate (adjust and tune) the CAS FORE-SIGHT Near-Infrared Spectroscopy (NIRS) monitor when used to measure the tissue oxygen saturation of internal organs (StO2).
- Trial name
- NCT00849940
- Testing
- CAS NIRS FORE-SIGHT oximeter
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Carotid Artery Disease, Carotid Artery Stenosis
The Gore SCAFFOLD Clinical Study
Evaluate the safety and efficacy of the GORE® Carotid Stent for the treatment of carotid artery stenosis in patients at increased risk for adverse events from carotid endarterectomy
- Trial name
- NCT01901874
- Testing
- Carotid Artery Stenting
- Where
- 2 sites in United States
- Volunteers
- 312 people
- Sponsor
- W.L.Gore & Associates
Carotid Artery Stenosis
GORE Embolic Protection With Reverse Flow
To compare the 30-day safety and efficacy of the GORE Flow Reversal System when used with approved carotid stents to an Objective Performance Criterion derived from distal embolic protection studies.
- Trial name
- EMPiRE (NCT00594100)
- Testing
- GORE Flow Reversal System (GFRS)
- Where
- 2 sites in United States
- Volunteers
- 245 people
- Sponsor
- W.L.Gore & Associates
Osteoarthritis
Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated Study
The primary objective of this investigation is to compare the precision of long leg alignment achieved by the two types of procedure.
- Trial name
- NCT00733330
- Testing
- Either P.F.C. Sigma or L.C.S. Complete knee replacement using the conventional surgical approach and manual surgical technique, Either P.F.C. Sigma or L.C.S. Complete knee replacement using minimally invasive surgical approach and computer navigation
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 86 people
- Sponsor
- DePuy International
COVID-19 Pandemic
Analysing the Psychosocial Effects of COVID-19 Pandemic on Dental Professionals Using the Turkish Version of the Fear of COVID-19 and Coronavirus Anxiety Scales
The aims of this study were to (i) assess fear and anxiety of COVID-19 in a Turkish sample dental professionals using the Turkish FCV-19S and CAS; (ii) explore factors associated with FCV-19S and CAS; and (iii) examine the…
- Trial name
- NCT04674644
- Testing
- The psychosocial effects of COVID-19 pandemic on dental professionals
- Where
- Turkey (Türkiye)
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Childhood Apraxia of Speech
ASSIST: Treatment for Childhood Apraxia of Speech
Childhood apraxia of speech (CAS) is a pediatric motor speech disorder that impairs the planning of movements needed for intelligible speech. Children with CAS often show little or slow progress in standard speech therapy.
- Trial name
- ASSIST (NCT03903120)
- Testing
- ASSIST
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Temple University