Clinical trials: CBT-I
Major Depressive Disorder, Suicide
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
Approximately four thousand Canadians die by suicide every year, and suicide is the second leading cause of death in youth and young adults (15-34 years).
- Conditions
- Major Depressive Disorder, Suicide, Treatment Resistant Depression
- Trial name
- Ket-CBT (NCT06480500)
- Testing
- Ketamine hydrochloride, i-CBT (Internet-based Cognitive Behavioural Therapy), Midazolam Hydrochloride
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- University Health Network, Toronto
Cancer Survivorship, Insomnia
Innovating CBT-I for Cancer Survivors: An Optimization Trial
The overall goal of this project is to conduct a factorial, randomized controlled trial to optimize synchronous, virtual delivery of CBT-I for cancer survivors.
- Trial name
- NCT06181643
- Testing
- Survivorship Sleep Program with Individual Delivery + No Booster Sessions, Survivorship Sleep Program with Group Delivery + No Booster Sessions, Survivorship Sleep Program with Individual Delivery + 3 Booster Sessions
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Chronic Pain, Insomnia
Digital CBT-I for Patients With Chronic Pain and Insomnia
Chronic pain constitutes an increasing health and social burden. More than 50% of patients with chronic pain report insomnia, and patients with comorbid insomnia often report stronger and widespread pain, compared to those who…
- Trial name
- Back2Sleep (NCT06361914)
- Testing
- Digital CBT-I, Digital Sleep hygiene education
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Insomnia, Cognitive Impairment
RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
The goal of the study is to investigate whether treating insomnia using app-based cognitive behavioral therapy for insomnia (CBT-I) can improve cognitive impairment in breast cancer survivors compared to an active control group…
- Conditions
- Insomnia, Cognitive Impairment, Breast Cancer
- Trial name
- RESET-BRAIN (NCT06553235)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep hygiene education
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Aarhus University Hospital
Chronic Insomnia
A Remote, 9-week Insomnia Treatment Trial to Collect Real World Data for a Digital Therapeutic
The purpose of the study is to collect data in a real-world environment, for a digital therapeutic that delivers CBT-I through a decentralized clinical trial, open to participants with chronic insomnia.
- Trial name
- DREAM (NCT04325464)
- Testing
- PEAR-003A
- Where
- United States
- Volunteers
- 1,590 people
- Sponsor
- Pear Therapeutics, Inc.
Chronic Insomnia Disorder, Chronic Insomnia
A Randomized, Single-Blind Study Evaluating the Efficacy and Cost-Effectiveness of Brief Behavioral Therapy for Chronic Insomnia Patients Under Medication Treatment At Nguyen Trai Hospital, Ho Chi Minh City
Insomnia disorder is considered quite common and is recognized as a risk factor for psychiatric disorders. In industrialized countries, chronic insomnia disorder is estimated to affect about 5-10% of the population, with some…
- Conditions
- Chronic Insomnia Disorder, Chronic Insomnia, BBT-I, CBT-I
- Trial name
- NCT06727916
- Testing
- BBT-I, Non BBT-I
- Volunteers
- 100 people
- Sponsor
- Nguyen Trai Hospital
Insomnia, Depression
Sleep Mechanisms Of Regulating Emotions
This project is the second phase of a two-phased project investigating the impact of a proven sleep intervention, Cognitive Behavioral Therapy for Insomnia (CBT-I) on engagement of the emotion regulation brain network as a…
- Trial name
- SleepMORE (NCT06373718)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Insomnia
Solriamfetol and CBT-I in Patients With Insomnia Disorder
Medication is FDA approved. The objective of this project is to test the efficacy of solriamfetol for treating insomnia (alone and in combination with Cognitive Behavioral Therapy for Insomnia [CBT-I]).
- Trial name
- NCT05838430
- Testing
- Solriamfetol 75 MG, Cognitive Behavioral Therapy for Insomnia (CBT-I), Monitoring
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Pennsylvania
Chronic Insomnia
Cognitive-Behavior Therapy for Insomnia
Insomnia is a prevalent public health problem affecting large segments of the population on an occasional, recurrent, or chronic basis.
- Trial name
- NCT00869934
- Testing
- Cognitive-Behavior Therapy, Behavior Therapy, Cognitive Therapy
- Where
- 2 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- Laval University
Anxiety, CBT
Optimizing CBT Implementation Among Community Providers Through Internet-based Consultation and Networking (i-CAN)
Although anxiety is one of the most common and debilitating mental health conditions affecting children and adolescents, the vast majority of sufferers do not receive effective treatment.
- Trial name
- NCT05580081
- Testing
- i-CAN
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
HIV - Human Immunodeficiency Virus, Insomnia Disorder
A Sleep Program to Improve Sleep Quality in People With HIV
Sleep problems, such as insomnia, are more frequent and intense in individuals living with HIV. These sleep difficulties can increase the difficulties in thinking and concentrating.
- Trial name
- NCT02571595
- Testing
- Digital cognitive behavioural therapy for insomnia (dCBT-I)
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- McGill University
Insomnia
Clinician Training Program to Integrate Digital CBTI Into Routine Psychotherapy
The goal of this study is to pilot test and refine a training program for licensed therapists to promote the integration of digital cognitive behavior therapy for insomnia (dCBTi) into their routine mental health care services.
- Trial name
- NCT05814783
- Testing
- supported digital CBTI, digital CBTI
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cancer, Insomnia
A Comparison of MBSR and CBT for the Treatment of Insomnia in Cancer
Sleep disturbance in cancer patients is often overlooked despite its documented high prevalence and negative impact. There are few empirically validated non-pharmacological treatments for insomnia and many patients are unwilling…
- Trial name
- I-CAN SLEEP (NCT01335776)
- Testing
- Mindfulness-Based Stress Reduction, Cognitive Behavior Therapy
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- University of Calgary
Bipolar Disorder, Insomnia
Cognitive Behavioral Therapy for Insomnia in Euthymic Bipolar Disorder
Patients with bipolar disorder suffer from sleep disturbances, even in euthymic phases. Changes in sleep are frequent signs of a new episode of (hypo)mania or depression.
- Trial name
- NCT01704352
- Testing
- Cognitive behavioral therapy for insomnia
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Norwegian University of Science and Technology
Sleep Architecture, Mild Traumatic Brain Injury
Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)
This study will employ cognitive behavioral therapy for insomnia (CBT-I) among individuals with mild traumatic brain injury (mTBI) who experience sleep disturbances.
- Conditions
- Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
- Trial name
- NCT07385105
- Testing
- Cognitive behavioral Therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Insomnia, Depression
Transdiagnostic CBT-I on Comorbid Depression and Insomnia
This randomized control trial (RCT) aims at comparing the efficacy of self-help cognitive behavioural therapy for insomnia (CBT-I) and self-help cognitive behavioural therapy for depression (CBT-D) on comorbid depression and…
- Trial name
- NCT05630261
- Testing
- Self-help CBT-I, Self-help CBT-D
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Older Adults (65 Years and Older)
CBT-I in Older African American Adults
Sleep problems, like insomnia, are common in older African Americans. About 25% of older adults in the US have at least 2 symptoms of insomnia, such as having trouble falling asleep, staying asleep, or getting good sleep for a…
- Trial name
- NCT06791356
- Testing
- Cognitive-behavioral therapy for insomnia, Sleep hygiene education
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Insomnia, Nightmare
Cognitive Behavioral Therapy for Insomnia vs. Exposure, Relaxation, and Rescripting Therapy
The objective of this project is to determine if directly addressing disturbed sleep and nightmares will impact client reports of suicidal ideation.
- Conditions
- Insomnia, Nightmare, Trauma
- Trial name
- NCT03831412
- Testing
- CBT-I, ERRT
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Tulsa
Insomnia, Anxiety
CBT-I Versus CBT-I+ACT for Youths With Insomnia and Anxiety
Insomnia in adolescents and youth is a long-standing public health concern due to its high prevalence and association with various physical and mental health problems.
- Conditions
- Insomnia, Anxiety, Youth
- Trial name
- NCT06156306
- Testing
- CBT-I, CBT-I combined ACT
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Insomnia
Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
This study aims to conduct a randomized control trial to validate the treatment effect of e-based cognitive behavioral therapy for Insomnia (e-CBT-I) on insomnia disorder, and explore whether e-CBT-I could prevent depression and…
- Trial name
- NCT04069247
- Testing
- e-CBT-I, e-HE
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 708 people
- Sponsor
- Chinese University of Hong Kong