Clinical trials: CBT-I
Posttraumatic Stress Disorders, Chronic Insomnia
Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)
This study aims to examine whether integrating insomnia and PTSD treatment will enhance sleep, PTSD, and quality of life outcomes.
- Trial name
- NCT02774642
- Testing
- CBTI-PE, Hygiene-PE
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- VA Office of Research and Development
Insomnia, Suicidal Ideation
RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
There is a strong association between insomnia and suicidal thoughts and behaviors. Insomnia also frequently co-occurs with other common conditions associated with suicide such as depression and posttraumatic stress disorder.
- Trial name
- NCT03603717
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
- Where
- 3 sites in United States
- Volunteers
- 283 people
- Sponsor
- VA Office of Research and Development
Cancer, Insomnia
Online Treatment of Cognitive Impairment and Insomnia in Cancer Survivors
The investigators will answer the question of whether treating insomnia using Cognitive Behavior Therapy for Insomnia (CBT-I) can improve perceived cognitive impairment (PCI) in cancer survivors compared to a waitlist control…
- Conditions
- Cancer, Insomnia, Cognitive Impairment
- Trial name
- NCT04026048
- Testing
- Cognitive Behaviour Therapy for Insomnia (CBT-I)
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Memorial University of Newfoundland
Insomnia
SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid
The objective of this study is to compare the efficacy of a sleep intervention on improving cognitive function in older adults with symptoms of insomnia, determine the association between change in sleep measures and change in…
- Trial name
- NCT03954210
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Insomnia, Pain
Treatment of Insomnia Secondary to Chronic Pain
Several studies have shown that behavioral therapy for chronic pain can be beneficial for chronic pain and that behavioral therapy for insomnia can be beneficial for insomnia.
- Trial name
- NCT00127790
- Testing
- CBT for Insomnia (CBT-I), CBT for Pain (CBT-P)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester
Breast Cancer Survivor, Insomnia
mHealth for Breast Cancer Survivors With Insomnia
The aim of this study is to determine the impact of the voice-activated smart speaker CBT-I components on insomnia symptoms among breast cancer survivors using a randomized clinical trial.
- Trial name
- NCT05233800
- Testing
- Faster Asleep Smart Speaker Program, Faster Asleep Website
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medstar Health Research Institute
Insomnia, Psychosis
CBT-I for Psychosis: Guidelines, Preliminary Efficacy, and Functional Outcomes
The goal of this project is to develop guidelines for the clinical tailoring of Cognitive Behavioral Therapy for Insomnia (CBT-I) for Veterans with psychotic disorders and insomnia, and to test the acceptability, feasibility, and…
- Trial name
- CBT-I (NCT02535923)
- Testing
- Cognitive Behavioral Therapy-Insomnia, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Primary Insomnia
The Role of Partial Reinforcement in the Long Term Management of Insomnia
The lack of scientific attention devoted to the placebo effect as a phenomenon in its own right probably reflects the paucity of theoretical positions within which to organize the existing data and design new research.
- Trial name
- ADER (NCT00662155)
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Pennsylvania
Insomnia, Mental Health Issue
Investigating a Sleep Intervention for Adolescents Attending Mental Health Services
The overall objectives of the study are to: 1. To assess the feasibility of delivering the Strathclyde Sleep Intervention to adolescents with co-morbid insomnia and mental health attending a mental health services The following…
- Trial name
- NCT05870228
- Testing
- Strathclyde Sleep Intervention
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Stephanie McCrory
Insomnia Chronic
Prescription Digital Therapeutic for the Treatment of Insomnia
This will be a prospective multi-center controlled trial of 100 patients conducted to assess the real-world effectiveness of a mobile-delivered, prescription digital therapeutic (PDT) device delivering Cognitive Behavioral…
- Trial name
- SLEEP-I (NCT04909229)
- Testing
- PEAR-003b PDT Intervention, Fitbit, Sleep education materials
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Marijuana Abuse, Sleep Initiation and Maintenance Disorders
CBT-I for Cannabis Use
The purpose of this study is to investigate the efficacy of a group-based behavioral sleep intervention, and the incremental benefit provided by an adjunct sleep mobile app, on cannabis and sleep outcomes among cannabis dependent…
- Trial name
- CBT-I-CU (NCT02102230)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Insomnia Plus Mobile App (CBT-I-MA), Desensitization Treatment for Insomnia
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- VA Office of Research and Development
Chronic Insomnia
CBT-I or Zolpidem/Trazodone for Insomnia
This study is a randomized (1:1:1) comparative effectiveness trial of medication (zolpidem or trazodone), cognitive-behavioral therapy for insomnia (CBT-I), and the combination (medication + CBT-I) for the treatment of chronic…
- Trial name
- COZI (NCT04468776)
- Testing
- Zolpidem, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), Trazodone
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- California Pacific Medical Center Research Institute
Insomnia, Depression
A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety
Several lines of evidence suggest that unhealthy sleep patterns contribute to depressive symptoms through disruption of brain networks that regulate emotional functions.
- Trial name
- NCT04424407
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Insomnia
Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
This study aims to conduct a randomized control trial to validate the treatment effect of e-based cognitive behavioral therapy for Insomnia (e-CBT-I) on insomnia disorder, and explore whether e-CBT-I could prevent depression and…
- Trial name
- NCT04069247
- Testing
- e-CBT-I, e-HE
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 708 people
- Sponsor
- Chinese University of Hong Kong
Insomnia, Alcohol Use Disorder
CBT-I on Alcohol Treatment Outcomes Among Veterans
Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.
- Trial name
- Project SAVE (NCT03806491)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Bipolar Disorder, Anxiety Disorders
Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
The specific goal of this research study is to investigate the feasibility, acceptability, and preliminary efficacy of a transdiagnostic, cognitive-behavioral therapy developed specifically to target common core processes across…
- Trial name
- NCT01892306
- Testing
- UP CBT, Treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Glioblastoma Multiforme, Anaplastic Glioma
Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)
The goal of this clinical research study is to learn if vorinostat when given with isotretinoin and temozolomide can help to control glioblastoma or gliosarcoma. The safety of these drug combinations will also be studied.
- Trial name
- NCT00555399
- Testing
- Vorinostat, Isotretinoin, Surgical Resection
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- M.D. Anderson Cancer Center
Insomnia
The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & Relapse
Insomnia is a highly prevalent disorder in those recovering from alcoholism. It has been associated with anxiety and depressive symptoms, as well as an increased risk of relapse back to the drinking.
- Trial name
- NCT01987089
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development