Clinical trials: CCSVI
Venous Irregularities, Flow and Perfusion in MS and Non-MS Participants
Venous Irregularities, Flow and Perfusion in MS Study
1. What is the true incidence of CCSVI in patients with MS in a study comparing MRI on MS patients and controls. 2. Are the beneficial outcomes from treatment placebo? By measuring changes in brain perfusion and Cerebrospinal…
- Trial name
- VERIFYMS (NCT01593904)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Synergy Health Concepts, Inc.
Chronic Cerebrospinal Venous Insufficiency
Doppler Sonography, MR Venography, Plethysmography for the Diagnosis of CCSVI
This study is aimed at evaluation of diagnostic value of Doppler sonography, MR venography and air-plethysmography for the assessment of abnormalities in the internal jugular veins, with catheter venography as the reference test.
- Trial name
- NCT01425554
- Testing
- Doppler sonography of internal jugular veins, Magnetic resonance venography of internal jugular veins, Air-plethysmography of the neck
- Where
- Poland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Euromedic Specialist Clinics, Poland
Multiple Sclerosis
Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients
This is a single center, multispecialty, randomized double blind placebo control feasibility clinical trial. The purpose is to evaluate the safety, feasibility and efficacy of percutaneous transluminal angioplasty in treating…
- Trial name
- NCT01089686
- Testing
- Venoplasty
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Manish Mehta, MD
Multiple Sclerosis, Neurodegenerative Diseases
Observational Study of the Prevalence of CCSVI in Multiple Sclerosis and in Other Neurodegenerative Diseases
The presence of abnormalities in the cerebral venous circulation, defined as Chronic Cerebrospinal Venous Insufficiency (CCSVI), has recently been reported in patients with Multiple Sclerosis (MS), in healthy subjects and in…
- Trial name
- COSMO (NCT01384825)
- Where
- 43 sites in Italy, Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondazione Italiana Sclerosi Multipla
Ehlers-Danlos Syndrome, Multiple Sclerosis
Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)
The investigators propose that evidence of chronic cerebrospinal venous insufficiency (CCSVI) may be evident in the vasculature of the fundus.
- Trial name
- NCT01356134
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Genetic Disease Investigators