Clinical trials: CES
Intraoperative Lung Protective Ventilation
Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic.
- Trial name
- IOLPVCZ (NCT07282899)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Myopia
Myopia Control Effect of DIMS Spectacle Lenses in Czech Children and Young Adults
The aim of this clinical study is to compare the efficacy of DIMS technology spectacle lenses with conventional single vision spectacle lenses at slowing the progression of myopia in the category of children and young adults…
- Trial name
- NCT05943912
- Testing
- Single Vision Spectacle Lens, Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Czech Technical University in Prague
Anxiety, Depression
Efficacy of CES in New Mothers During the Post Partum Period
The birth of a child is a major life event that can be filled with excitement, anticipation and joy. However, the transition and adaptation to new demands, roles, responsibilities, and changes in relationships can be stressful…
- Conditions
- Anxiety, Depression, Insomnia, Sleep Quality
- Trial name
- NCT03210155
- Testing
- Alpha-Stim AID CES (Active Comparator)
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Christina Murphey, RN, PhD
Obesity
A Study to Understand the Distribution of Obesity Classes and Obesity Related Diseases in People With Obesity Across Countries in Czech Republic, Hungary and Poland
The study is intended to understand the distribution of different obesity classes and obesity related diseases (diseases that present along with obesity) in patients with body mass index (BMI) ≥ 30 kg/m^2.
- Trial name
- ExplorEUEast (NCT05795166)
- Testing
- No treatment given
- Volunteers
- 1,241 people
- Sponsor
- Novo Nordisk A/S
Chronic Obstructive Airway Disease
Czech Multicentre Research Database of Chronic Obstructive Pulmonary Disease (COPD)
The chronic obstructive pulmonary disease (COPD) is the occurrence of chronic bronchitis or emphysema, a pair of commonly co-existing diseases of the lungs in which the airways narrow over time.
- Trial name
- NCT01923051
- Where
- 14 sites in Czechia
- Volunteers
- 813 people
- Sponsor
- Zuzana Zbožínková, M.Sc.
Delirium
Delirium in the (Neuro)Intensive/Critical Care in the Adult and Paediatric Czech Populations
Intensive and critical care in the intensive care unit (ICU) is often associated with ICU delirium and post-ICU dementia, regardless of the nature of the primary disease or insult.
- Trial name
- NCT05891873
- Testing
- CAM-ICU, ICDSC, 4AT
- Where
- Czechia
- Volunteers
- 700 people
- Sponsor
- Masaryk University
Restless Legs Syndrome
Cranial Electrotherapy for Military Beneficiaries With Restless Legs Syndrome
The purpose of this study is to assess the feasibility and effectiveness of Cranial Electrical Stimulation (CES) therapy in treating symptoms of Restless Legs Syndrome (RLS).
- Trial name
- CES in RLS (NCT02419014)
- Testing
- Active CES Device Alpha-Stim®
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Tripler Army Medical Center
Preterm Labor, Preterm Birth
Cervical Stiffness in Women With Threatened Preterm Labor
Women giving birth prematurely due to spontaneous preterm labor may exhibit signs and symptoms of preterm labor (PTL) which are mostly nonspecific.
- Trial name
- CZECH-TPTL (NCT07840235)
- Testing
- Pregnolia System
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Pregnolia AG
Depression
The Safety and Efficacy of Nexalin Trans-cranial Electrical Stimulation Stimulation for the Treatment of Depression
The purpose of this research study is to determine whether Nexalin Trans-Cranial Electrical Stimulation (TES) is an effective treatment for depression among patients who are candidates for ECT.
- Trial name
- TES (NCT03277846)
- Testing
- Nexalin Based Trans-Cranial Electrical Stimulation
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Pennsylvania
Anxiety State
Cranial Electrotherapy Stimulation and Acute Stress
The goal of this study is to quantify the effects of 20 sessions of Cranial Electrotherapy Stimulation (CES) on measures of acute stress responses in Soldiers.
- Trial name
- NCT06034496
- Testing
- Active CES
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tufts University
Non Hodgkin Lymphoma (NHL)
Non-Hodgkin Lymphoma - Observational Epidemiological and Clinical Study (NiHiL)
The Czech National Lymphoma Registry (NiHiL) was founded to monitor epidemiologic data and improve the diagnostic evaluation and quality of treatment of patients with non-Hodgkin´s lymphoma (NHL).
- Trial name
- NCT03199066
- Where
- Czechia
- Volunteers
- 20,000 people
- Sponsor
- Czech Lymphoma Study Group
Psychiatric Disorder
Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers
This clinical trial evaluates the effect of life coaching together with Cranial Electrotherapy Stimulation (CES) as an intervention to decrease self-reported symptoms of burnout, moral distress, resilience, and employee retention…
- Trial name
- NCT06977503
- Testing
- Cranial Electrical Stimulation (CES), Discussion, Health and Wellness Coach
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
COVID, SARS-CoV 2
COVID-19: Herd Immunity Study in the Czech Republic
The aim of the SARS-CoV-2-CZ-Preval study is to quantify the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on…
- Trial name
- SARSCoV2CZPrev (NCT04401085)
- Testing
- SARS-CoV-2 diagnostic rapid test, Quantitative analysis of SARS-CoV-2 antibodies
- Where
- Czechia
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Inflammatory Cardiomyopathy
CZECH-ICIT (CZECH Inflammatory Cardiomyopathy Immunosuppression Trial)
The aim of this study is to compare the effect of combined immunosuppressive therapy given on the top standard medical therapy of chronic heart failure according to current guidelines with standard medical therapy of chronic…
- Trial name
- NCT01877746
- Testing
- Combination of prednisone and azathioprine, No intervention
- Where
- 2 sites in Czechia
- Volunteers
- 234 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Gastro Esophageal Reflux
Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids)
This study aims to determine the prevalence of symptomatic gastroesophageal reflux disease (GERD) in children aged 8-9 years and 12-13 years in the Czech Republic.
- Trial name
- Czech GERDKids (NCT07482969)
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Motol
Lung Cancer
Early Detection of Lung Cancer in Czech High-risk Asymptomatic Individuals
The aim of this study is to evaluate and optimize entry criteria for the proposed programme for early detection of lung cancer in the Czech Republic.
- Trial name
- ELEGANCE (NCT04627350)
- Testing
- Response to pulmonary finding (nodule, mass)
- Where
- Czechia
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Major Depressive Disorder Co-Occurrent With Anxiety, Adult Patients
First choIce Antidepressants: General Practitioner's Treatment Approach in the Czech Republic
According to the local guidelines (Recommendation for General Practitioners), the first choice Anti-Depressant (AD) in Major Depressive Disorder (MDD) in primary care should be selective serotonin reuptake inhibitors (SSRI), e.g.
- Conditions
- Major Depressive Disorder Co-Occurrent With Anxiety, Adult Patients, Newly Diagnosed Depression
- Trial name
- FIAT (NCT05291897)
- Where
- 6 sites in Czechia
- Volunteers
- 28 people
- Sponsor
- Angelini Pharma Česká republika s.r.o.
Major Depressive Disorder
Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder
Efficacy of Cranial Electrotherapy Stimulation (CES) for the treatment of Major Depressive Disorder
- Trial name
- NCT03222752
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Motor Activity
Establishing Czech Norms of Selected Standardized Tests
The main aim of the project is to establish Czech updated manuals for the Nine Hole Peg Test, Purdue Pegboard Test and Box and Block Test to be used in rehabilitation to evaluate upper limb functions, including establishing norms…
- Trial name
- NCT05010993
- Testing
- Nine Hole Peg Test, Purdue Pegboard Test, Box and Block Test
- Where
- Czechia
- Volunteers
- 689 people
- Sponsor
- Charles University, Czech Republic
Breast Cancer Surgery
Localization of Breast Cancer with the Sirius Pintuition Magnetic Seed
A prospective pilot study in the Czech Republic examining the use of magnetic seed Sirius Pintuition for the localization of non-palpable malignant breast tumors and pathological lymph nodes.
- Trial name
- NCT06799858
- Testing
- Breast cancer localisation with magnetic seed Sirius Pintuition
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Jan Žatecký