Clinical trials: CLBP - Chronic Low Back Pain
Low Back Pain, Multifidus
Effects of Isolated Lumbar Extension Resistance Training Alone and in Combination with General Exercise and Manual Therapy
This study examines effects of machine-based isolated lumbar extension resistance exercise (ILEX) on paraspinal muscle morphology and function, as well as pain intensity, disability and quality of life in patients with chronic…
- Conditions
- Low Back Pain, Multifidus, Exercise Therapy, Diagnostic Imaging
- Trial name
- NCT06890052
- Testing
- Targeted exercise program, Targeted exercise as part of an integrative therapy program
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Low Back Pain
Predictors of Chronic Non-specific Low Back Pain
Chronic non-specific low back pain (CNSLBP) has been defined as a persistent pain in the lower back for at least three months with no known causes. The CNSLBP prevalence is estimated of 90% among all types of the LBP.
- Trial name
- NCT02932163
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Work-related Illness
Effectiveness of Ergonomic Training and Exercise in Automotive Factory Workers With Nonspecific Chronic Low Back Pain
This study compares the effectiveness of ergonomic training and exercise in automotive factory workers with chronic low back pain of unknown cause.
- Trial name
- NCT06864650
- Testing
- Ergonomics training, exercise program
- Where
- Ireland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Low Back Pain, Core Stability
Lumbar School Training or Core Stabilization Exercises on Pain, Mobilization and Quality of Life Low Back Pain
Chronic low back pain (CLBP) is defined as low back pain lasting longer than three months. CLBP is one of the most common and expensive diseases in terms of both labour loss and treatment costs, and it is very important to treat…
- Conditions
- Low Back Pain, Core Stability, Core-based Exercise, Back School
- Trial name
- Lowbackpain (NCT06203340)
- Testing
- Core stabilizasyon and lumbal back school
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Low Back Pain, Kinesio Taping
Acute Effect of Myofascial Release and Kinesiology Taping
Chronic low back pain (LBP) is one of the leading causes of activity limitation and disability. The prevalence of chronic CBA among young adults is known to increase, and a recent epidemiological study reported a rate of 42.4%…
- Conditions
- Low Back Pain, Kinesio Taping, Myofascial Release Technique
- Trial name
- NCT05319184
- Testing
- Myofascial Release Technique and Kinesiology Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Low Back Pain (non-specific, Uncomplicated), Walking
Exploring Locomotion Behavior of Chronic Non-Specific Low Back Pain (cNSLBP) Patients While Walking Through Apertures in Different Configurations: Influence of Environmental and Social Factors.
The biomechanical parameters studied in chronic non-specific low back pain (cNSLBP) patients in a locomotion task have so far focused on straight line walking.
- Trial name
- PERL3 (NCT06644053)
- Testing
- Quantified analysis of walking during a crossing task through different horizontal openings
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Chronic Low-back Pain, Walking
Locomotion Strategies of Low Back Pain Patients
The biomechanical parameters studied in non-specific chronic low back pain patients in a locomotion task have so far focused on straight line walking.
- Trial name
- NCT05337995
- Testing
- Quantified analysis of walking during a task of passage through a horizontal opening
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Non-specific Chronic Low Back Pain
Relationships Between Muscle Activity, Soft Tissue Changes, and Movement Strategies in Individuals With Chronic Low Back Pain
This study aims to explore, in patients with chronic non-specific low back pain (cnsLBP), the relationships between lumbar muscle activity, structural and morphological characteristics of the paraspinal muscles, and movement…
- Trial name
- E-LBP (NCT07806253)
- Testing
- Supervised Progressive Walking Test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Chronic Low Back Pain
Pilates and Resistance Training for Pain, Disability, and Sleep in Chronic Low Back Pain
This study will investigate the effect of Pilates and resistance training on pain, disability, and sleep quality in patients with chronic low back pain and sleep disturbances.
- Trial name
- NCT07291934
- Testing
- Combined Intervention (Pilates + Resistance Training), Pilates, Control (Usual Care)
- Where
- Palestinian Territories
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Low-back Pain
Effectiveness of Cat-Cow Yoga in Managing Chronic Low Back Pain
A randomized control trial is planned to investigate the effectiveness of Cat-Cow yoga as a treatment for chronic low back pain CLBP.
- Trial name
- NCT04723225
- Testing
- Cat-Cow Yoga
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Osteoarthritis Pain, Chronic Low Back Pain
Study To Assess Changes In The Number Of Nerves In The Skin At The Site Where Where Tanezumab Is Injected
Subcutaneous administration of tanezumab can result in changes in the number of nerves around the injection site in the thigh.
- Conditions
- Osteoarthritis Pain, Chronic Low Back Pain, Pain Due to Interstitial Cystitis
- Trial name
- NCT01030640
- Testing
- tanezumab
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Chronic Low Back Pain
Botulinum Toxin A for the Treatment of Chronic Lumbar Back Pain
This study will assess the efficacy and the duration of efficacy of Botulinum toxin A (Botox®) injected into the lumbar paraspinal muscles for reducing pain and disability in subjects suffering from chronic low back pain of six…
- Trial name
- NCT00404417
- Testing
- Botulinum Toxin A / Botulinum Toxin A
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Chronic Low Back Pain
Effectiveness of Electrotherapy Techniques to Treat Low Back Pain
Objective: The aim of this investigation was compare the effectiveness of transcutaneous electrical nerve stimulation (TENS) and interferential currents (IC) on chronic low back pain.
- Trial name
- TENBACK (NCT02297685)
- Testing
- Transcutaneous nerve stimulation, Interferential currents
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Camilo Jose Cela University
Low Back Pain
Measurement of Spinal Kinematics During Various Movements
Participants will perform movements while receiving different visual cues. Spinal kinematics will be measured during these movements and compared between asymptomatic and CLBP participants.
- Trial name
- NCT04334889
- Testing
- Visual cues
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Haute Ecole de Santé Vaud
Chronic Low Back Pain
Stanford Spine Keeper - Managing Your Low Back Pain
Mobile health applications (mHealth apps) are transforming medical research and intervention by allowing constant, instantaneous and personalized access to patients.
- Trial name
- NCT05443503
- Testing
- Mobile health applications (mHealth apps) based intervention
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Stanford University
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Low Back Pain
Reliabılıty,Validity Of The Turkish Version Of The NIH-Minimal Dataset
This study, we performed the Turkish version validity and reliability of the NIH Task Force's Recommended Multidimensional Minimal Dataset
- Trial name
- NCT06049719
- Testing
- NIH Task Force's Recommended Multidimensional Minimal Dataset
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Gazi University
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Low Back Pain
H-reflex Responses to High-Velocity Low-Amplitude Manipulation
High-Velocity Low-Amplitude (HVLA) manipulation is a known technique of the Osteopathic Manipulative Treatment (OMT) for somatic dysfunction (SD), and heart rate variability and H-reflex response are possible variables to assess…
- Trial name
- NCT02406807
- Testing
- HVLA manipulation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Osteopatia