Clinical trials: CMC Arthritis
Arthritis
Study Comparing SBS and LRTI for Treatment of CMC Arthritis
A multi-center, randomized control trial comparing the two standard of care surgical treatments for CMC arthritis ; trapezial excision with or without soft tissue interposition and /or ligament reconstruction (LRTI) versus the…
- Trial name
- SBSvsLRTI (NCT05111405)
- Testing
- CMC Arthroplasty
- Where
- 2 sites in Canada
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Fraser Orthopaedic Research Society
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the first CMC joint in the hand compared to LRTI.
- Trial name
- GRIP 2 (NCT03247439)
- Testing
- Cartiva
- Where
- 9 sites in United States, United Kingdom
- Volunteers
- 74 people
- Sponsor
- Cartiva, Inc.
Osteoarthritis
Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC
This multicenter, double-blind, randomized, parallel-group, active-controlled trial will be performed in approximately 80 subjects with chronic idiopathic osteoarthritis (OA) of the first carpo-metacarpal joint (CMC).
- Trial name
- NCT00423371
- Testing
- sodium hyaluronate
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Ferring Pharmaceuticals
Osteoarthritis in the Carpometacarpal (CMC) Joint
CMC-1 Replacement Arthroplasty Versus Trapeziectomy
Thumb carpometacarpal (CMC-1) osteoarthritis is a common condition causing pain and disability, particularly among middle-aged and older women. When non-operative treatment fails, surgery is indicated.
- Trial name
- NCT07583628
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Thumb Osteoarthritis
Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis
Long-Term Objective: Determine if high-frequency PEMF therapy reduces pain in patients with thumb carpometacarpal (CMC) joint osteoarthritis (OA).
- Trial name
- NCT05315297
- Testing
- PEMF device
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Stanford University
Osteoarthritis
CMC (Carpometacarpal) OA (Osteoarthritis) Thumb Splint Study
Osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is a common condition that is seen regularly in outpatient occupational therapy and physiotherapy departments.
- Trial name
- NCT00705146
- Testing
- Comfort Cool thumb splint by North Coast Medical, Custom made thermoplastic & neoprene splint
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of British Columbia
Thumb Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis.
- Trial name
- NCT05992883
- Testing
- Ketorolac, Triamcinolone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
CMC Arthritis
Thumb Metacarpophalangeal Hyperextension in an Arthritic Population; Part 2
This is the second phase of a clinical study to assess MP hyperextension in CMC arthritis. In the first phase, submitted for publication, the investigators demonstrated that there is poor correlation between dynamic control of…
- Trial name
- NCT05835830
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana Hand to Shoulder Center
Pain, Osteoarthritis
Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis
In this clinical trial, females with a diagnosis of thumb CMC OA, will be recruited. The primary outcome of potential risk factors of osteoarthritis, pain and function will be measured using the demographic data, visual analog…
- Trial name
- CMC (NCT03821298)
- Testing
- Standard of Care Hand Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gannon University
Arthritis Wrist
Orthotic Management of CMC Osteoarthritis
This study will investigate the effectiveness of 3D printed splints for the treatment of thumb osteoarthritis (CMC OA). Currently, these splints are made by Occupational Therapists and Physical Therapists out of low temperature…
- Trial name
- NCT04297943
- Testing
- Orthosis fabrication, Thermal Sensor Monitoring of Orthosis Use, 4D CT Scan
- Volunteers
- 68 people
- Sponsor
- Western University, Canada
CMC Arthritis
Predictive Outcomes for Selective Thumb Carpometacarpal Joint Denervation
Background: The thumb (or first) carpometacarpal (CMC) joint is commonly affected by osteoarthritis. Literature has reported a prevalence of 15% in women and 7% in men.
- Trial name
- NCT06467669
- Testing
- Wrist denervation procedure
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Osteoarthritis
Ligament Reconstruction in an Accelerated Rehabilitation Protocol
The investigators have found that their patients who get earlier rehabilitation following ligament reconstruction and tendon interposition (LRTI) surgery with interference screws have experienced better outcomes.
- Trial name
- NCT05571241
- Testing
- Fast rehabilitation program
- Where
- Canada
- Sponsor
- Dr. David Pichora
Thumb Osteoarthritis
Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision-Making
This is a retrospective cohort study utilizing radiographic and computed tomography (CT) imaging data collected during routine clinical care at Schulthess Klinik Zürich.
- Trial name
- TMCAI (NCT07148349)
- Testing
- No Intervention: Observational Cohort
- Where
- Switzerland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Carpometacarpal (CMC) Joint Arthritis
Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting
The oval-8 splint has been developed for many uses in finger pathology and trauma. It has not, however, been used to treat thumb carpometacarpal (CMC) joint arthritis.
- Trial name
- Oval-8 (NCT02266095)
- Testing
- Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
CMC Arthritis, Occupational Therapy
Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?
The study is a randomized, controlled trial to evaluate the efficacy of formal occupational therapy on outcomes following CMC arthroplasty
- Conditions
- CMC Arthritis, Occupational Therapy, Hand Arthritis
- Trial name
- NCT06820528
- Testing
- Occupational Therapy, Home Exercise Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Julie Nuelle
Carpometacarpal (CMC) Joint Arthritis, Ganglion Cyst
The Correlation of Clinical and Ultrasonographic Findings in Dorsoradial Wrist Pain Patients: Cross Sectional Study
This study aims to investigate the correlation between ultrasonographic and clinical findings in dorsoradial wrist pain. There are several etiologies for dorsoradial wrist pain, including carpometacarpal joint arthritis, De…
- Conditions
- Carpometacarpal (CMC) Joint Arthritis, Ganglion Cyst, De Quervain Disease, Radial Neuropathy
- Trial name
- NCT06980779
- Testing
- ultrasonographic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Osteoarthritis, Osteoarthritis Thumb Base Joint
Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis
The goal of this study is to determine the success rate of a single Carpometacarpal (CMC) thumb injection after arthroplasty surgery for primary osteoarthritis of the CMC joint.
- Conditions
- Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
- Trial name
- CTM CMC (NCT06171529)
- Testing
- CTM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana Hand to Shoulder Center
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Use of FlexHD as Post Trapeziectomy Spacer
The objective of this study is to show that using FlexHD® (or HADM) to fill the empty space created by removal of the trapezium improves the subject's outcome and subsequent functionality of the basilar joint arthroplasty…
- Trial name
- MTF (NCT01998594)
- Testing
- Arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Anomaly; Hand
The Prevalence of the Linburg-Comstock Variation
The purpose of this study is to explore the physical exam characteristics of patients referred to orthopedic surgeons with a diagnosis of thumb carpometacarpal (CMC) arthritis.
- Trial name
- LCV (NCT06142370)
- Testing
- Descriptive
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Russell Sage College