Clinical trials: CMT
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Thoracic Outlet Syndrome
Assessment of the Impact of Thoracic Outlet Syndromes on the Performance at Work
Thoracic outlet syndrome may associate neurologic, arterial and venous symptoms. The responsibility of repetitive movements and postural factors has been mentioned for long.
- Trial name
- PROCTB (NCT03780647)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Carpal Tunnel Syndrome
Carpal Tunnel Release Using Ultrasound
The goal of the Carpal Tunnel Release Using Ultrasound registry (CiTRUS Registry) is to collect experience information from patients scheduled to undergo carpal tunnel release surgery with either the SX-One MicroKnife® with…
- Trial name
- CiTRUS (NCT05031338)
- Testing
- Carpal Tunnel Release
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Sonex Health, Inc.
Stroke
Effect of Transcranial Direct Current Stimulation (tDCS) on Post-stroke Patients on Neuromotor Recovery
The aim of the study is to evaluate whether a non-invasive brain stimulation technique (Transcranial Direct Current Stimulation) can influence the secondary neurodegeneration observed after a stroke (assessed based on serum…
- Trial name
- NCT05821816
- Testing
- tDCS, Conventional rehabilitative treatment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Musculoskeletal Disorder, Rotator Cuff Tendinitis
Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality
This study assess ocular movements in a hand laterality judgment task in a population of musculoskeletal disorders. Reaction time, error rate and visual strategy are compared between musculoskeletal disorders and healthy…
- Conditions
- Musculoskeletal Disorder, Rotator Cuff Tendinitis, Chronic Low Back Pain, Carpal Tunnel Syndrome
- Trial name
- Schem-TMS (NCT03567109)
- Testing
- hand laterality judgment task
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Angers
Charcot-Marie-Tooth Disease, Hereditary Neuropathy With Hypersensitivity to Pressure
EVALUATION OF SERUM INFLAMMATORY CYTOKINE CONCENTRATION IN HEREDITARY SENSITIVOMOTOR NEUROPATHIES
The most common forms of hereditary neuropathy are Charcot-Marie-Tooth disease (CMT) and hereditary neuropathy with hypersensitivity to pressure (HNPP) or tomacular neuropathy.
- Trial name
- CytokinesUS (NCT06808581)
- Testing
- blood test for pro-inflammatory cytokines and ultrasound of the median nerves
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Breast Cancer, Peripheral Neuropathy, Secondary to Drugs or Chemicals
Chemotherapy Induced Peripheral Neuropathy. Could Physical Therapy Help Treat Symptoms?
The cause of Chemotherapy-Induced Peripheral Neuropathy (CIPN) is still unknown. An estimated 55-60% of patients will experience lasting symptoms affecting function for years post-treatment.
- Trial name
- NCT02239601
- Testing
- Physical Therapy
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- CancerCare Manitoba
Idiopathic Carpal Tunnel Syndrome
Comparison of Subjective Outcomes and Changes of Ultrasonographic Morphology of Median Nerves of Mini-open and Endoscopic Carpal Tunnel Release in Patients With Idiopathic Carpal Tunnel Syndrome
A few studies have shown that the mini-incision release technique decreases the pathologic swelling of the median nerve at the inlet of the carpal tunnel and increases the flattening ratio of the median nerve in the carpal…
- Trial name
- NCT01972165
- Testing
- Mini-incision carpal tunnel release, Endoscopic carpal tunnel release
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Yonsei University
Carpal Tunnel Syndrome (CTS), Wrist
Analysis of Radiographic Indices in Carpal Tunnel Syndrome
The aim of this study was to compare wrist radiographic indices in patients with idiopathic carpal tunnel syndrome (CTS) with normal cases.
- Conditions
- Carpal Tunnel Syndrome (CTS), Wrist, X-Ray, Radiography
- Trial name
- NCT06841809
- Where
- Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Ankara Training and Research Hospital
Carpal Tunnel Syndrome, Neurodynamic Treatment
Mechanisms of Neurodynamic Treatments
INTRODUCTION: Carpal tunnel syndrome (CTS) is a relatively common condition caused by compression of one of the main nerves at the wrist, the median nerve.
- Conditions
- Carpal Tunnel Syndrome, Neurodynamic Treatment, Nerve Mobilisation, Diffusion MRI
- Trial name
- MONET (NCT05859412)
- Testing
- Neurodynamic exercises, Steroid injection (Depomedrone 40mg), Advice
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Carpal Tunnel Syndrome
IMpact of Perineural Hydrodissection Over Alternative Therapies in Patients With Carpal Tunnel Syndrome
This is a multidisciplinary, single-blinded, three-arm randomized controlled trial, comparing perineural hydrodissection and steroid injection for the treatment of CTS.
- Trial name
- IMPACTS (NCT03616353)
- Testing
- Perineural Hydrodissection, Corticosteroid Injection
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Leslie Witton
Cluneal Syndrome
Proximal Versus Distal Superior Cluneal Nerve Block in Entrapment Neuropathy
Superior cluneal nerve (SCN) entrapment is an underdiagnosed cause of chronic low back and gluteal pain. Although diagnostic nerve block is considered the gold standard for confirming SCN entrapment, there is no consensus…
- Trial name
- NCT07372430
- Testing
- Ultrasound-guided distal superior cluneal nerve injection, Ultrasound-guided proximal superior cluneal nerve injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome Treated With 830nm Diode Laser
The purpose of this study is to determine that 830nm diode laser directly above the transverse carpal ligament (between the pisiform and navicular bone) on subjects' wrists, and test this therapeutic effect.
- Trial name
- CTS (NCT00514462)
- Testing
- diode laser
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Thoracic Outlet Syndrome
Ultrasonographic Evaluation of Osteopathic Manipulation for Thoracic Outlet Syndrome
The purpose of the study is to develop a protocol to assess blood flow in the upper limb vasculature before and after osteopathic manipulative treatment (OMT) using Pulsed-wave Doppler ultrasonography (US).
- Trial name
- TOS (NCT06273969)
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- A.T. Still University of Health Sciences
Thoracic Outlet Syndrome, Mechanically Loaded Neuro-dynamics
Effect of Mechanically Loaded Neuro-dynamics in Subjects With Thoracic Outlet Syndrome
the study was done to: To assess the effect of Mechanically Loaded Neuro-dynamics on pain reduction in subjects with thoracic outlet syndrome.
- Trial name
- NCT07785427
- Testing
- Mechanically Loaded Neuro-dynamics, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Spinal Muscular Atrophy
Antisense Oligonucleotide for Spinal Muscular Atrophy
This is a longitudinal, multiple-center, observational study of patients genetically confirmed chromosome 5q SMA to monitor the efficacy, safety, tolerability of SPINRAZA® (nusinersen) for up to 24 months.
- Trial name
- NCT05187260
- Testing
- Nusinersen
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Low Back Pain, Nerve Entrapment Syndrome
The Frequency of Superior Cluneal Nerve Entrapment Diagnosed With Ultrasound Guided Nerve Block
Cluneal nerves are a group of pure sensory nerves that provide direct cutaneous innervation to the buttocks. Superior cluneal nerve(SCN) originates from the T11-L5 nerve roots and has at least 3 branches from medial to lateral…
- Conditions
- Low Back Pain, Nerve Entrapment Syndrome, Radiating Pain
- Trial name
- NCT05303597
- Testing
- ultrasound-guided diagnostic nerve block with lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University - Cerrahpasa
Frontotemporal Dementia (FTD), GRN Related Frontotemporal Dementia
Predict to Prevent PGRN Disease
Progranulin (GRN or PGRN) mutations are among the most common genetic causes of frontotemporal lobar degeneration (FTLD). With the advent of gene-specific therapeutic interventions, an accurate knowledge of the presymptomatic…
- Trial name
- PREVENT-PGRN (NCT06711510)
- Testing
- Clinical, behavioral and cognitive evaluation, blood sampling, brain MRI
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pudendal Neuralgia
Conus Medullaris Stimulation With 5 Columns Lead Versus Medical Treatment in Refractory Pudendal Neuralgia
Pudendal neuralgia is a frequent diagnosis in pain clinics. This perineal pain has devastating effects on patient's quality of life. Today, 30% of patients are refractory to pain management and surgical procedure.
- Trial name
- STIMCONE (NCT02564172)
- Testing
- CMS group, OMM group
- Where
- 7 sites in France
- Volunteers
- 42 people
- Sponsor
- Nantes University Hospital
Piriformis Syndrome
f-ESWT vs Steroid Injection for Piriformis Syndrome
This study aims to compare two treatment methods for piriformis syndrome, a condition that can cause pain in the buttock and leg. Adult patients with piriformis syndrome will take part in the trial.
- Trial name
- NCT07145554
- Testing
- Focal extracorporeal schock wave therapy, Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulhane Training and Research Hospital