Clinical trials: CMT
Charcot Marie Tooth Disease
Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease
The object of this research is to test the effectiveness of Coenzyme Q10 (CoQ10) on symptoms of weakness, fatigue, and pain in persons with Charcot-Marie-Tooth disease (CMT).In this study we also intend to examine the impact of…
- Trial name
- NCT00541164
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Memorial Medical Center
Most Common Musculoskeletal Problems in Pregnancy
Musculoskeletal Problems During Pregnancy
Aim: This study was conducted to identify the most common musculoskeletal problems according to trimester, experienced by pregnant women.
- Trial name
- NCT04496206
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Eskisehir City Hospital
Unilateral Carpal Tunnel Syndrome
Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves
This study is being done to see how well a new investigational medical device, the StimRouter (STR) System, will work to treat the chronic pain in people who have failed previous treatments for Carpal Tunnel Syndrome (CTS) pain…
- Trial name
- StimRouter (NCT00665132)
- Testing
- StimRouter System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Bioness Inc
Cumulative Trauma Disorders, Carpal Tunnel Syndrome
Protective Brace to Prevent Hand and Arm Injuries
When people use hand-held power tools, their hands and arms vibrate along with the tool they are holding. People who frequently use hand-held power tools may develop injuries related to this vibration.
- Trial name
- NCT00074893
- Testing
- piezoelectric wrist brace
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Carpal Tunnel Syndrome, Patient Satisfaction
Postoperative Care After Carpal Tunnel Release Using Short Educational Videos
The goal of this clinical trial is to learn if a patient-directed postoperative care program, using short educational videos, can improve patient satisfaction and reduce healthcare resource utilization in patients undergoing…
- Trial name
- VIDEO (NCT06647719)
- Testing
- Educational Videos
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Carilion Clinic
Refractory Carpal Tunnel Syndrome, Neurpathic Pain
Short and Long Term Exposure to Unique, Time-Varying Pulsed Electro-Magnetic Fields in Refractory Carpal Tunnel Syndrome
Pulsed electromagnetic fields (PEMF) have been approved by FDA and are utilized currently in treating non-union fractures, neurogenic bladder and musculoskeletal pains.
- Conditions
- Refractory Carpal Tunnel Syndrome, Neurpathic Pain, Neuromodulaton
- Trial name
- NCT00277563
- Testing
- reduction of pain scores by magnetic energy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Thoracic Outlet Syndrome
Immediate Effects of Kinesio Taping on Thoracic Outlet Syndrome
The goal of this clinical trial is to evaluate the immediate effects of Kinesio Taping compared with sham taping in adults with Thoracic Outlet Syndrome (TOS).
- Trial name
- NCT07750184
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Thoracic Outlet Syndrome
Evaluation of the Muscular FORCE in the Upper Limbs of Patients Presenting a Thoracic Outlet Syndrome
The thoracic outlet syndrome is a rare but debilitating pathology, responsible for upper limb pain. Its frequency is probably underestimated because of diagnostic difficulties.
- Trial name
- EFORD (NCT04145778)
- Testing
- 6-minute walk test
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Carpal Tunnel Syndrome
The Effectiveness of Stretching and Orthoses in Individuals With Carpal Tunnel Syndrome
The objective of this study is to compare the effectiveness of stretching and prefabricated orthoses versus orthoses alone in individuals with carpal tunnel syndrome (CTS) using validated condition-appropriate outcome measures…
- Trial name
- NCT05838989
- Testing
- Prefabricated Orthoses, general and lumbrical muscle stretching
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ahram Canadian University
Bardet Biedl Syndrome (BBS), Alström Syndrome (AS)
Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity
This pivotal, phase 3 study is designed to confirm the efficacy and safety of setmelanotide, a potent melanocortin receptor type 4 (MC4R) agonist, for the treatment of obesity and hyperphagia in participants with Bardet Biedl…
- Trial name
- NCT03746522
- Testing
- Setmelanotide
- Where
- 12 sites in United States, Canada and 4 more
- Volunteers
- 52 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Motor Neuron Diseases, Spinocerebellar Ataxias
Rare Disease Registry Database for Movement Disorders in Southern Anhui Province
According to the World Health Organization (WHO) definition, a rare disease is a disease affecting fewer than 6.5 people per 10,000; in China, it generally refers to diseases with a prevalence of less than 1/10,000 (i.e., with a…
- Conditions
- Motor Neuron Diseases, Spinocerebellar Ataxias, Hereditary Muscular Dystrophy, Hereditary Spastic Paraplegia
- Trial name
- W-MoSCA (NCT07838883)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Carpal Tunnel Syndrome
Validation of PSFS in Carpal Tunnel Syndrome
Validation of the Patient Specific Functional Scale in patients with carpal tunnel syndrome
- Trial name
- NCT03909373
- Testing
- PSFS
- Where
- United States
- Sponsor
- Stanford University
Carpal Tunnel Syndrome
Hand10 Questionnaire in Individuals With Carpal Tunnel Syndrome
Hand10 questionnaire, Boston Carpal Tunnel Syndrome Questionnaire and Arm Shoulder Questionnaire for patients with carpal tunnel syndrome and Hand Deficiencies Questionnaire (DASH) will be applied one week apart to investigate…
- Trial name
- NCT05916456
- Testing
- The Hand10 Questionnaire, DASH Questionnaire, Boston carpal tunnel syndrome questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Hasan Kalyoncu University
Piriformis Syndrome
Sacroiliac Joint Manipulation Effect in Chronic Piriformis Syndrome.
The objective of the study was to determine the effects of sacroiliac joint thrust manipulation on pain, pain pressure threshold, piriformis length and straight leg raise, in chronic piriformis syndrome.
- Trial name
- NCT04603703
- Testing
- HVLAT Manipulation, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Thoracic Outlet Syndrome
Electromyography in Thoracic Outlet Syndrome
Record the ENMG data carried out systematically in patients treated by rehabilitation for thoracic outlet syndrome in order to assess their characteristics and judge the relevance of these data in the context of the diagnosis and…
- Trial name
- ENMG-AFC (NCT05360303)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Nantes University Hospital
CMT1A
Ulipristal Acetate In Disease Charcot-Marie-Tooth Type of 1A
The disease Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common inherited peripheral neuropathy, for which no treatment has proved its effectiveness.
- Trial name
- UPACOMT (NCT02600286)
- Testing
- EllaOne
- Where
- 5 sites in France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Strasbourg, France
Charcot-Marie-Tooth Disease
Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease
This is a multicenter, phase 2 study to evaluate the safety, tolerability, pharmacodynamics (PD), efficacy, and pharmacokinetics (PK) of ACE-083 in patients with Charcot-Marie-Tooth Disease Type 1 and Type X (CMT1 and CMTX), to…
- Trial name
- NCT03124459
- Testing
- ACE-083
- Where
- 16 sites in United States
- Volunteers
- 63 people
- Sponsor
- Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
Carpal Tunnel Syndrome
Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electrophysiological and Ultrasonographic Measurements in Carpal Tunnel Syndrome
This study is aimed to investigate the effects of upper extremity manual lymphatic drainage, which is applied to remove edema from the carpal tunnel region in addition to conventional exercise therapy in Carpal tunnel syndrome…
- Trial name
- NCT05490420
- Testing
- manual lymphatic drainage (MLD)
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Istanbul Medeniyet University
Carpal Tunnel Syndrome, Pregnancy Related
The Effect of Splints in Pregnant Women With Carpal Tunnel Syndrome
It is aimed to compare the effect of two different splints on carpal tunnel syndrome in pregnant individuals after 4 weeks of use.
- Conditions
- Carpal Tunnel Syndrome, Pregnancy Related, Splints
- Trial name
- NCT06131996
- Testing
- Volar supported splint, elastic splint
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Mardin Artuklu University
Diabetic Neuropathy, Neuropathic Pain
Pain In Neuropathy Study
In the context of peripheral neuropathy, we will aim to elucidate correlates between sensory symptoms and: Sensory nerve dysfunction. Cutaneous small nerve fibre innervation density. Psychological co-morbidity.
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Chronic Pain, Carpal Tunnel Syndrome
- Trial name
- PINS (NCT02672059)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- King's College London