Clinical trials: CONTROL Condition
Type II Diabetes Mellitus
A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral HMS5552 in Healthy Volunteers
The objectives of this study is to determine the safety profiles, tolerability, pharmacokinetics and pharmacodynamics of HMS5552 following single ascending doses in healthy adult subjects.
- Trial name
- NCT01952535
- Testing
- HMS5552
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hua Medicine Limited
Tobacco Dependence
Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
The purpose of this study is to test the safety, tolerability, compliance and efficacy of two different forms of nicotine replacement therapy (NRT) (the nicotine transdermal patch and the nicotine gum) in a nicotine-dependent…
- Trial name
- NCT01208935
- Testing
- Nicotine Patch, Nicotine Gum
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Restless Legs Syndrome
Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome
The purpose of this study is to explore whether patients with restless legs syndrome (RLS) differ from healthy subjects in daytime and night time autonomic function and cardiovascular risk markers and whether 4 week treatment…
- Trial name
- AUTOREST (NCT02025608)
- Testing
- Pramipexole
- Where
- 2 sites in Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mauro Manconi
Intermittent Hypoxia
Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude
Low oxygen at altitude causes pauses in breathing during sleep, called central sleep apnea. Central sleep apnea causes repeated awakenings and poor sleep.
- Trial name
- NCT03588676
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Robert L. Owens
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Digital Game Addiction, Sleep Deprivation
School-Based Self-Regulation Intervention for Digital Game Addiction and Sleep Deprivation
This study evaluates the effectiveness of a school-based self-regulation intervention designed to reduce digital game addiction and sleep deprivation among adolescents aged 10-14 years.
- Conditions
- Digital Game Addiction, Sleep Deprivation, Problematic Digital Gaming, Adolescent Behavioral Health
- Trial name
- SRDGA (NCT07423689)
- Testing
- School-Based Self-Regulation Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Turkan Akyol Guner
Soil-transmitted Helminth Infections
Community Health Education and Hygiene Promotion Added to Deworming Among Ethnic Khmer Children in Vietnam
This study evaluated whether adding community health education and household hygiene promotion to supervised deworming could improve soil-transmitted helminth (STH) outcomes and related caregiver and household factors among…
- Trial name
- NCT07855978
- Testing
- Albendazole 400 mg, Community Health Education and Hygiene Promotion
- Where
- 4 sites in Vietnam
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Osteoporosis
The Postprandial Calcium Absorption of a Milk Derived Calcium Permeate - RENEW Acute Study
This is a randomized controlled cross-over meal study with the overall aim to investigate the postprandial calcium absorption from calcium permeate compared with calcium carbonate.
- Trial name
- NCT04550078
- Testing
- Calcium Carbonate, Calcium Permeate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Inge Tetens
Malaria,Falciparum
Vectron T500 (Broflanilide 50WP) for IRS in Tanzania Tanzania
Malaria is a major public health problem in Africa. An important way to control the disease is by Indoor Residual Spraying of insecticide in houses. Insecticide resistance has become a major problem.
- Trial name
- NCT05150808
- Testing
- IRS insecticide: Vectron T500
- Where
- 2 sites in Tanzania, United Kingdom
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Periodontitis, Intrabony Periodontal Defect
Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread.
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect
- Trial name
- NCT07146776
- Testing
- open flap debridement with I-prf and xenogeneic graft, open flap debridement with saline and xenogenic graft
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Hypothermia, Shivering
Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean Sectıon
This research was planned to determine the effect of acupressure on hypothermia and shivering after cesarean section. H01: There is no difference in hypothermia findings between women who received acupressure and women in the…
- Conditions
- Hypothermia, Shivering, Postoperative Hypothermia, Postoperative Shivering
- Trial name
- NCT07864376
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Bone Resorption
Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group C ) A Randomized Controlled Clinical Trial
20 patients were selected requiring implant placement and divided randomly into two groups (10 in each group) for the study group, starter drill is used to locate the point of insertion as planned then pilot drill is also used to…
- Trial name
- NCT03220789
- Testing
- Drilling at low speed, Drilling at conventional or high speed
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gestational Diabetes Mellitus
Improving Cardio-metabolic and Mental Health in Women With Gestational Diabetes Mellitus and Their Offspring
MySweetHeart Trial is a randomized controlled trial to test the effect of a multidimensional interdisciplinary lifestyle and psychosocial intervention to improve the cardio-metabolic and mental health of women with GDM and their…
- Trial name
- MySweetHeart (NCT02890693)
- Testing
- interdisciplinary lifestyle and psychosocial intervention
- Where
- Switzerland
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Influenza
Safety and Immunogenicity of Two Adjuvanted and One Non-adjuvanted H5N1 Influenza Vaccine in Adults
The present study aims to evaluate safety and immunogenicity of two doses, administered three weeks apart, and a 6 month booster dose, of two influenza vaccines containing 7.5 micrograms or 15 micrograms of H5N1 influenza…
- Trial name
- NCT00382187
- Testing
- MF59 adjuvanted H5N1 influenza vaccine
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Appendicitis, Surgery
Raja Isteri Pengiran Anak Saleha Appendicitis Treatment Without Operation
The RIPASA score is a Clinical Prediction Rule (CPR) for the diagnosis of acute appendicitis. Since its inception in 2009, the RIPASA score has been validated in various population in healthcare institutions around the world and…
- Trial name
- RIPASA-TWO (NCT03169114)
- Testing
- Amikacin Injection, Appendicectomy
- Where
- Brunei
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Raja Isteri Pengiran Anak Saleha Hospital
Postoperative Acute Pain, Chronic Pain
Comparison of Postoperative Analgesic Efficacy of Interscalene and Suprascapular Blocks Used in Arthroscopic Shoulder Surgery
The Importance of Postoperative Analgesia in Shoulder Surgery Shoulder surgery is an orthopedic procedure that can be performed either through open surgery or arthroscopically.
- Trial name
- NCT07483814
- Testing
- rescue analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Disease, Infectious, Respiratory Disease
Effectiveness and Safety of Respiratory Training in the Prevention and Severity of COVID-19
A randomized controlled clinical trial will be carried out using inspiratory and expiratory training devices on healthy subjects recruited in social networks and university environments.
- Conditions
- Disease, Infectious, Respiratory Disease, Safety Issues, Effectiveness
- Trial name
- NCT04326114
- Testing
- Inspiratory training device, Expiratory training device
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
COVID-19, COVID-19 Acute Respiratory Distress Syndrome
The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.
Aim: This study was conducted to determine the effect of listening to music during CPAP on the agitation levels of intensive care patients who underwent CPAP due to COVID-19 and their compliance with the treatment.
- Trial name
- NCT05102084
- Testing
- Listening to music with a bluetooth headset to patients receiving CPAP support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- SÜMEYYE BİLGİLİ
Dementia Prevention
Dementia Prevention Internet-Based Intervention: Randomized Controlled Trial and Knowledge Translation
In this proposal, the investigators plan to study the effectiveness of a web-based intervention on dementia prevention knowledge, intentions, and behaviour change related to dementia risk.
- Trial name
- NCT06911047
- Testing
- Education Intervention, Education Control
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
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