Clinical trials: CONTROL Condition
Body Fat Disorder
Impact of Oral Dyglomera™ on Body Fat and Blood Lipids of Overweight and Obese Adults
The extract of Dichrostachys glomerata (DyglomeraTM), has been reported to be effective in weight reduction in obese patients with metabolic syndrome.
- Trial name
- Dyglomera (NCT05483192)
- Testing
- Oral Dyglomera
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gateway Health Alliance
Malaria,Falciparum, Anemia in Children
Comparing Chemoprevention Drugs for School-based Malaria Control
This is an individually randomized, controlled, single blind three arm clinical trial of malaria chemoprevention strategies Arm 1: Intermittent preventive treatment with dihydroartemisinin-piperaquine (IPT-DP).
- Trial name
- NCT05980156
- Testing
- Dihydroartemisinin-Piperaquine, Chloroquine, Sulfadoxine pyrimethamine
- Where
- Malawi
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Insulin Resistance, Type 2 Diabetes
The Influence of Overfeeding Different Macronutrients on Whole-body Insulin Sensitivity
This study will investigate the effect of high-carbohydrate vs. high-fat overfeeding (130% of energy requirements) on whole body insulin sensitivity.
- Conditions
- Insulin Resistance, Type 2 Diabetes, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- NCT03863431
- Testing
- High-fat diet, High-carbohydrate diet
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Recalcitrant Cutaneous Warts
Oral Zinc Gluconate as Treatment for Recalcitrant Cutaneous Warts: A Randomized, Double-blind, Placebo-controlled Trial
Up to one-third of common warts can remain recalcitrant, an occurrence that has been attributed to impaired cell-mediated immunity. At present, no guidelines exist for the management of recalcitrant cutaneous warts.
- Trial name
- NCT01783353
- Testing
- Zinc gluconate, Corn starch pill
- Where
- Philippines
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Philippine Dermatological Society
Antenatal Care and Delivery
Increasing Women's Access to Skilled Pregnancy Care to Reduce Maternal Mortality in Nigeria
Background: Nigeria has the second highest absolute number of maternal deaths and perinatal deaths in the world. The country contributes 14% of all maternal deaths worldwide, second only to India.
- Trial name
- NCT02643953
- Testing
- Incentives, Community
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Temperature Regulation; Disorder, Fetus or Newborn
Effect of Drying Before Plastic Wrapping on Thermal Losses in Very Preterm Infants at Birth
This is a multicenter, unblinded, randomized controlled trial comparing drying vs. not drying before plastic wrapping for the thermoregulation of very preterm infants at birth.
- Trial name
- NEODRY (NCT05740072)
- Testing
- Drying before wrapping, No drying before wrapping
- Where
- Italy
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Respiratory Syncytial Virus Infections
Safety, Tolerability, Pharmacokinetics, and Food Effect Study of RV299 in Healthy Adults
The main aims of the study are to assess the safety, tolerability, pharmacokinetics and food effects of RV299 compared to Placebo in healthy adult participants.
- Trial name
- NCT06033612
- Testing
- RV299, Midazolam
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pfizer
Skin Tightening, Skin Laxity
Efficacy of Long Pulsed 1064nm Laser for Facial Skin Tightening
We study the efficacy of 1 pass of stacking pulses of long pulse 1064nm laser on the face for skin tightening immediately post laser and 3 months follow up.
- Conditions
- Skin Tightening, Skin Laxity, Wrinkle Reduction
- Trial name
- NCT01971736
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Convulsion, Non-Epileptic
Treatment Outcomes of ReACT for PNES
This research study is examining the effects of Retraining and Control Therapy (ReACT; an intervention focused on changing behaviors and thoughts) for psychogenic non-epileptic seizures (PNES, episodes resembling epileptic…
- Trial name
- NCT02801136
- Testing
- ReACT, Supportive Therapy
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Skin Barrier Disruption and Recovery
Helichrysum Italicum Extract in Irritant Contact Dermatitis
The goal of this clinical trial is to evaluate the efficacy and safety of a topical cream containing Immortelle (Helichrysum italicum) extract in promoting skin barrier recovery and reducing signs of irritant contact dermatitis…
- Trial name
- NCT07676253
- Testing
- Helichrysum italicum Extract Cream
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Migraine
A Phase 1 Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-313 in Healthy Participants
This first in-human (FIH) study of UB-313, an anti-calcitonin gene-related peptide based immunotherapeutic candidate, is designed to assess the safety, tolerability, and immunogenicity of 4 selected UB-313 dose regimens in…
- Trial name
- NCT05477095
- Testing
- UB-313
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Axxium Life, Inc.
Adenoma, Pain
The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate
Water exchange method has been shown to reduce medication requirement and pain experienced during colonoscopy. It may increase the adenoma detection rate (ADR).
- Trial name
- NCT02135601
- Testing
- Water colonoscopy
- Where
- 6 sites in China
- Volunteers
- 3,303 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Non Restorative Sleep, Sleep Disorder (Disorder)
Sleep Promoting Properties of a Botanical Extract in a Population Complaining From Non-Restorative Sleep (NRS)
The goal of this clinical trial is to evaluate the effect of the Botanical Extract in improving sleep symptoms of nonrestorative sleep (NRS) in healthy adults.
- Trial name
- NCT07085819
- Testing
- Botanical Extract, 125mg, Botanical Extract, 250mg, Botanical Extract, 500mg
- Where
- Ireland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kerry Group P.L.C
Pancreatitis, Acute Necrotizing
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Investigation of GSK3335065 Intravenous (IV) Infusion in Healthy Adults
GSK3335065 is being developed as a treatment for acute pancreatitis with the intent of reducing 3-hydroxykynurenine (3HK) levels to the normal range (or lower) and maintaining them at this level throughout the treatment period.
- Trial name
- NCT03245619
- Testing
- GSK3335065
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy, Hypoxia
Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion
To validate the proposed claims for pulse rate and saturation accuracy in a diverse subject population during motion over a specified saturation range.
- Trial name
- NCT02247765
- Testing
- Arterial line, Motion
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Migraine
Ascending Single Doses of Erenumab (AMG 334) in Healthy Adults and Migraine Patients
The primary purpose of this study is to determine whether erenumab is safe and well tolerated in healthy adults and migraine patients.
- Trial name
- NCT01688739
- Testing
- Erenumab
- Where
- Belgium
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Amgen
Aging, Sarcopenia
Effects of a Buriti Supplement on Body Composition and Function in Older Adults
Aging is a natural process commonly associated with loss of muscle mass, reduced flexibility, and impaired balance, directly affecting the quality of life of older adults.
- Conditions
- Aging, Sarcopenia, Malnutrition Elderly
- Trial name
- NCT07716839
- Testing
- Nutricer® Supplementation, Tai Chi Chuan program
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Aneurysmal Subarachnoid Hemorrhage
Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages
Aneurysmal subarachnoid hemorrhage (aSAH) is a dreadful acute neurological condition with overwhelmingly high rate of associated morbidities and mortality.
- Trial name
- HASH (NCT06548477)
- Testing
- Human albumin
- Where
- Qatar
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
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