Clinical trials: CONTROL Condition
Alcohol Exposed Pregnancy
Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled Trial
The EARLY Randomized Controlled Trial (RCT) will test the finalized EARLY preventive intervention against one comparison and one control condition.
- Trial name
- EARLY RCT (NCT01446653)
- Testing
- Motivational Interviewing plus feedback, Video, Informational Brochure
- Where
- 2 sites in United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Analgesia
Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy
Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）. Method: This study is a randomized, single-blind, controlled clinical trial.
- Trial name
- NCT04648345
- Testing
- Erector spinal plane block
- Volunteers
- 90 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Macular Edema Secondary to Central Retinal Vein Occlusion
Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)
This is a phase 3 study to determine the efficacy of VEGF Trap-Eye injected into the eye on vision function in subjects with macular edema as a consequence of central retinal vein occlusion.
- Trial name
- NCT00943072
- Testing
- VEGF Trap-Eye 2.0mg
- Where
- 61 sites in United States, Canada and 3 more
- Volunteers
- 189 people
- Sponsor
- Regeneron Pharmaceuticals
Presbyopia
An Evaluation of the Safety of CSF-1 in Presbyopic Subjects
This is a multi-center, double-masked, vehicle-controlled study. The purpose of the study is to evaluate the safety of CSF-1 compared with vehicle in presbyopic subjects. Subjects will be treated for at least 6 weeks.
- Trial name
- NCT05393895
- Testing
- CSF-1, Vehicle
- Where
- 12 sites in United States
- Volunteers
- 178 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Neck Pain
Effects of Radio-frequency in Patients With Myofascial Chronic Neck Pain
The aim of this study was to evaluate the potential clinical benefits of Monopolar Capacitive Resistive Radio-frequency (448 kHz) (MCRR)F for the treatment of myofascial chronic neck pain.
- Trial name
- NCT02353195
- Testing
- Radiofrequency
- Volunteers
- 50 people
- Sponsor
- Universidad Rey Juan Carlos
Oncology, Cancer-related Cognitive Impairment
Effects of Cognitive Training on Chemotherapy-Induced Cognitive Impairment in Colon Cancer Patients Undergoing Treatment(Chemobrain) in Oncology Patients With Colon Cancer Undergoing Active Treatment
Introduction: With the increasing survival rate in colon cancer, as a result of technological and biomedical advancements, it is essential to thoroughly study the secondary symptoms related to the oncological disease process.
- Conditions
- Oncology, Cancer-related Cognitive Impairment, Cognitive Training, Everyday Cognition
- Trial name
- NCT06710639
- Testing
- Health Education Program, Cognitive Training Program
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Asthma
Evaluation of Safety and Tolerability of BI 894416 in Patients With Mild Asthma
In both parts, the primary comparisons of interest are between the percentage of patients with drug-related adverse events at each dose and placebo during single and multiple dosing regimens.
- Trial name
- NCT03971539
- Testing
- BI 894416
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Boehringer Ingelheim
Encephalitis, Tick-Borne
Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children
The purpose of this study is to evaluate the safety, immunogenicity and tolerability of TBE vaccines administered to children.
- Trial name
- NCT00311441
- Testing
- Tick-Borne Encephalitis vaccine
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Novartis
Septic Shock
Esmolol Infusion for Patients With Septic Shock and Persistent Tachycardia
This is a prospective, single arm, "roll-in" study of esmolol infusion for patients with septic shock with persistent tachycardia after adequate intravenous volume expansion.
- Trial name
- ECASSS-R (NCT02841241)
- Testing
- Esmolol
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Intermountain Health Care, Inc.
Milk Allergy
Impact of Infant Formula on Resolution of Cow's Milk Allergy
Primary Endpoint -The percentage of subjects who develop tolerance to cow's milk protein by 12 months post randomization to study formula.
- Trial name
- NCT02719405
- Testing
- Lactobacillus GG, Extensively Hydrolyzed Casein Formula, Amino Acid Formula
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Massachusetts General Hospital
Renal Failure Chronic
Probiotics and Low Protein Diet in Advanced Chronic Kidney Disease
Here the investigators will perform a double-blinded randomized placebo-controlled clinical trial to evaluate the synergic effect of low protein diet and prebiotics in reducing the microbial inflammatory uremic toxins.
- Trial name
- ProLowCKD (NCT04204005)
- Testing
- Probiotics
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Probiotical S.p.A.
Rheumatic Diseases, Inflammatory Arthritis
Personalized Outreach for Equitable Treatment in Rheumatology
The primary goal of this study is to determine whether providing patient honoraria and/or outreach services can improve the attendance rate of appointments at an inner city rheumatology clinic in Vancouver, British Columbia.
- Conditions
- Rheumatic Diseases, Inflammatory Arthritis, Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA)
- Trial name
- POET-Rheum (NCT07022756)
- Testing
- Honoraria, Outreach
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis
Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients
The primary objective is to comparatively evaluate the isolated effects of a long-acting beta2-adrenergic (formoterol fumarate 12µg b.i.d.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis, Pulmonary Emphysema
- Trial name
- NCT00680056
- Testing
- Formoterol plus Tiotropium
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of São Paulo
Abnormal Uterine Bleeding, Chronic Pelvic Pain
Comparing Effectiveness of Oral Misoprostal for Cervical Priming in Hysteroscopy
Research objective To compare effectiveness of oral Misoprostal for cervical priming in premenopausal women underwent to diagnostic hysteroscopy Research hypothesis: Null hypothesis Effectiveness of oral misoprostal for cervical…
- Conditions
- Abnormal Uterine Bleeding, Chronic Pelvic Pain, Infertility, Female
- Trial name
- NCT03638856
- Testing
- Misoprostol 200Mcg Tab
- Where
- Thailand
- Volunteers
- 17 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Physical Inactivity, Occupational Stress
Braining - Physical Exercise in Psychiatry - Evaluation of Feasibility, Implementation and Health Among Staff
Physical exercise (PE) shows beneficial effects on somatic and psychiatric symptoms. "Braining" is a clinical invention where psychiatric staff exercise together with patients to help patients start and execute PE regularly.
- Trial name
- NCT05111756
- Where
- Sweden
- Volunteers
- 49 people
- Sponsor
- Region Stockholm
Anesthesia, Airway Remodeling
GMA-Tulip, I-gel and the LMA-Supreme (LMA-S) Devices in Airway Management (GLAM-I)
Patients were randomly assigned to three supraglottic airway devices (SADs) groups for airway management after anesthesia induced.
- Trial name
- GLAM-I (NCT06383494)
- Testing
- LMA supreme group, I-gel group, GMA-Tulip
- Where
- China
- Volunteers
- 498 people
- Sponsor
- Zhejiang Cancer Hospital
Type 2 Diabetes
Single Ascending Dose Study With Healthy Male Volunteers and Type II Diabetic Patients
The purpose of this study is to assess safety and tolerability of AZD6714 after single ascending oral doses in healthy male subjects and type 2 diabetic patients.
- Trial name
- NCT00886366
- Testing
- AZD6714
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Bipolar Disorder
Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)
The purpose of this study is to determine if flexibly-dosed ziprasidone is safe and effective for the treatment of children and adolescents (ages 10-17) with bipolar I disorder (manic or mixed).
- Trial name
- NCT00257166
- Testing
- Ziprasidone oral capsules
- Where
- 50 sites in United States
- Volunteers
- 238 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Fatigue Syndrome (CFS)
Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This is a 16-week controlled treatment trial of an over-the -counter supplement, hydrogen water, for individuals with ME/CFS patients. An active treatment condition will be compared to a placebo-control condition.
- Trial name
- ME/CFS (NCT07753122)
- Testing
- Molecular hydrogen produced by a metallic magnesium tablet, consumed 3x a day dissolved in water. Treatment duration is 16 weeks.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Fred Friedberg
Hepatocellular Carcinoma
Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)
The primary objective of this study is to assess the efficacy of SIRT as compared with Sorafenib in patients with locally advanced liver cancer in terms of overall survival (OS).
- Trial name
- SIRveNIB (NCT01135056)
- Testing
- SIR-Spheres, Sorafenib tosylate
- Where
- 29 sites in Brunei, Burma and 10 more
- Volunteers
- 360 people
- Sponsor
- Singapore General Hospital
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