Clinical trials: CONTROL Condition
Dermatitis, Allergic Contact
Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis
The purpose of this study is to compare the effect and safety of rHuPH20 or placebo for the prevention and treatment of skin allergic reaction to nickel. The study drug and placebo will be administered by intradermal injection.
- Trial name
- NCT00928447
- Testing
- rHuPH20
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Halozyme Therapeutics
Congenital Heart Disease
Impact of a Cardiac and Mental Health Rehab Program on Well-Being and Fitness in Young Adults With Fontan Circulation: A Randomized Trial
Helping Young Adults With Fontan Circulation Feel Better and Stay Active What is the study about? This study looked at how a special program could help young adults with Fontan circulation feel better mentally and physically.
- Trial name
- (NCTXXXXXXXX) (NCT06844149)
- Testing
- CPR; (Cardiac and Psychosocial Rehabilitation) with Cardiac Rehabilitation, CR; Home-Based Cardiac Rehabilitation, Usual Care
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Hepatitis C Viral
Oral Microbiome of Patients With Hepatitis C Virus Infection
Hepatitis C virus (HCV) infection is very common in Egypt and the middle east. The disease affects multiple body organs and may proceed to hepatocellular carcinoma.
- Trial name
- NCT03682549
- Testing
- Oral microbiome analysis
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity
Effects of Greenselect Phytosome® on Weight Maintenance After Weight Loss in Obese Women
This study evaluates whether supplementations with a highly bioavailable green tea extract may help obese women to counteract weight regain after a 3-month weight loss intervention.
- Trial name
- NCT02542449
- Testing
- Globes®
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Auxologico Italiano
Asthma
Systemic Corticosteroids Avoidance Study in Severe Asthma Patients
The overall purpose of this study was to determine the efficacy of fevipiprant (150 mg and 450 mg once daily), compared with placebo, as add-on to standard-of-care asthma therapy, in terms of avoidance of corticosteroid use over…
- Trial name
- NCT03629249
- Testing
- QAW039 150 mg once daily, QAW039 450 mg once daily
- Where
- 120 sites in United States, Argentina and 19 more
- Volunteers
- 604 people
- Sponsor
- Novartis Pharmaceuticals
Respiratory Insufficiency, Pneumonia
Evaluation of a Disposable Flexible Bronchoscope, aScope IV
Flexible bronchoscopes are typically reusable and therefore need high level disinfection to prevent inadvertent spread of microbial pathogens from patient to patient. The process of disinfection is time consuming and expensive.
- Conditions
- Respiratory Insufficiency, Pneumonia, Atelectasis
- Trial name
- EVAL (NCT02255838)
- Testing
- Bronchoscope reusable (Storz 8402 2x), Bronchoscope disposable (aScope 4)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Louisville
Sleep Apnea, Obstructive
Study to Evaluate Recovery From Postoperative Pain After Sleep Apnea Surgery
The purpose of this study is to assess whether tonsillectomy and UPPP performed using the study device to treat Obstructive Sleep Apnea (OSA) symptoms in adults is associated with less postoperative pain during the 21-day…
- Trial name
- NCT00380458
- Testing
- Coblation (radiofrequency-based device)
- Where
- United States
- Sponsor
- ArthroCare Corporation
Coronary Artery Disease
Pycnogenol and Endothelial Function in Coronary Artery Disease
Pycnogenol® is a proprietary bark extract of the French maritime pine tree (Pinus pinaster ssp. atlantica). Pycnogenol® has prevented pathologic symptoms such as chronic inflammation and increased platelet aggregation, a risk…
- Trial name
- NCT00641758
- Testing
- Pycnogenol
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Zurich
Ankylosing Spondylitis
Wet Cupping Therapy in Ankylosing Spondylitis
This study evaluates the efficacy of wet cupping therapy in patients with ankylosing spondylitis.Wet cupping therapy will be applied to half of the patients plus routine pharmaceutical treatment while the other half will receive…
- Trial name
- NCT05792358
- Testing
- wet cupping therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Tooth Demineralization
Study of Treatments Used for White Spot Lesions After Orthodontic Treatment.
The purpose of this study is to learn more about the management of white spot lesions that occur after orthodontic treatment. White spot lesions generally improve slightly with time.
- Trial name
- NCT01059058
- Testing
- MI Paste Plus, PreviDent Fluoride Varnish, Normal Home Care
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Washington
Schizophrenia, Schizoaffective Disorder
Shared Decision Making for Antipsychotic Medications
This study aims to provide an evidence-based shared decision making intervention for antipsychotic medications, the Antipsychotic Medication Decision Aid (APM-DA), for individuals experiencing early psychosis and provide, for the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders, Delusional Disorder
- Trial name
- NCT05416658
- Testing
- The Antipsychotic Medication Decision Aid (APM-DA)
- Volunteers
- 120 people
- Sponsor
- New York State Psychiatric Institute
Fibromyalgia
Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia
To evaluate the efficacy of NYX-2925 versus placebo for the treatment of fibromyalgia.
- Trial name
- NCT04147858
- Testing
- NYX-2925
- Where
- 42 sites in United States
- Volunteers
- 310 people
- Sponsor
- Aptinyx
HIV/AIDS, Psychological Trauma
Efficacy of EMDR Therapy, as Compared to Treatment as Usual, in Reducing Clinical Symptoms in People With HIV
People living with HIV may suffer HIV-related psychological trauma. Studies also show that this group is vulnerable to non-HIV-related trauma. Trauma can increase vulnerability to stress and reducing the ability to cope.
- Conditions
- HIV/AIDS, Psychological Trauma, PTSD
- Trial name
- NCT03848858
- Testing
- EMDR plus TAU
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Parc de Salut Mar
Reproductive Health
Effects of Dry Heat Application for Menstrual Symptoms
This randomized controlled trial was to determine the effect of dry heat applied on foot base of the 65 nursing students on menstrual symptoms and pain.
- Trial name
- NCT05664048
- Testing
- Dry heat application
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Class II Malocclusion
Modified Herbst Approach to Improve Chin Projection
This study will collect data to try to assess which one of the two management options works better. The first option involves the use of the bite corrector first and then braces, while the second option involves the temporary…
- Trial name
- NCT05597748
- Testing
- Modified Herbst Approach, Conventional Herbst Approach
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Juvenile Chronic Arthritis
Juvenile Rheumatoid Arthritis
The purpose of this study is to determine the safety of anakinra in patients with Polyarticular-Course Juvenile Rheumatoid Arthritis, a form of rheumatoid arthritis affecting children.
- Trial name
- NCT00037648
- Testing
- Anakinra
- Volunteers
- 86 people
- Sponsor
- Amgen
Bleeding, Surgery
Trial of PCC Versus FFP in Patients Undergoing Heart Surgery
The PROPHESY trial is a single centre pilot trial investigating Fresh Frozen Plasma (FFP) or Prothrombin Complex Concentrate (PCC) treatment for patients who are bleeding during cardiac surgery, and who are NOT receiving a…
- Conditions
- Bleeding, Surgery, Transfusion
- Trial name
- PROPHESY (NCT03715348)
- Testing
- Prothrombin Complex Concentrate (PCC), Fresh Frozen Plasma
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Queen Mary University of London
Membranous Nephropathy, Nephrotic Syndrome
Belimumab With Rituximab for Primary Membranous Nephropathy
The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete or partial remission (CR or PR) compared to rituximab alone in participants with…
- Trial name
- REBOOT (NCT03949855)
- Testing
- Belimumab, Rituximab
- Where
- 20 sites in United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Migraine Headache
A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches
To study the effect of Rozerem, a high affinity MT1 and MT2, low affinity 5-HT2B receptor agonist used for insomnia, as a migraine prophylactic agent.
- Trial name
- NCT00391755
- Testing
- ramelteon
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Charlottesville Neuroscience
Erectile Dysfunction
Combination Therapy of Tadalafil 2.5mg Plus Sildenafil 25mg Versus Tadalafil 5 mg Monotherapy for Treatment of Erectile Dysfunction: A Randomized, Placebo-Controlled Double-Blinded Cross-Over Study
Erectile dysfunction (ED) is characterized by the persistent inability to attain or sustain an erection adequate for satisfactory sexual intercourse.
- Trial name
- NCT07177326
- Testing
- Tadalafil 2.5 mg, Sildenafil 25 mg, Tadalafil 5 mg
- Volunteers
- 142 people
- Sponsor
- Assiut University
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