Clinical trials: CONTROL Condition
Type 2 Diabetes, Chronic Obstructive Pulmonary Disease
Probiotic on Type 2 Diabetes and Chronic Obstruction Pulmonary Disease
This trial is a randomized, double-blind, parallel placebo clinical trial, the purpose of which is to investigate whether the adjuvant therapy of using probiotics during the treatment of diabetic patients can decrease blood sugar…
- Trial name
- NCT05492448
- Testing
- L. salivarius AP-32 and L. reuteri GL-104, L. reuteri GL-104
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Glac Biotech Co., Ltd
Hypercholesterolemia
LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe
Eprotirome (KB2115) is a liver selective thyroid hormone that can induce hyperthyroidism in the liver, while an euthyroid state is preserved in the extrahepatic tissue.
- Trial name
- NCT00677248
- Testing
- Eprotirome and ezetimibe
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karo Bio AB
Barretts Esophagus With Dysplasia, Barrett Esophagus
Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia
The purpose of this study is to learn the best approach to treating patients with known or suspected Barrett's esophagus by comparing endoscopic surveillance to endoscopic eradication therapy.
- Conditions
- Barretts Esophagus With Dysplasia, Barrett Esophagus, Esophageal Adenocarcinoma
- Trial name
- SURVENT (NCT05753748)
- Testing
- Endoscopic Eradication Therapy
- Where
- 30 sites in United States
- Volunteers
- 680 people
- Sponsor
- University of Colorado, Denver
Hyperlipidemias
Effect of ANKASCIN 568-P Products Regulating Blood Lipid
This study is a randomized, double-blind, placebo-controlled, parallel-controlled trial (24 weeks in total), divided into three periods (screening, treatment, and discontinuation follow-up)
- Trial name
- NCT05737355
- Testing
- ANKASCIN 568-P Red yeast rice capsules
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- SunWay Biotech Co., LTD.
Bloating, Rifaximin
Rifaximin Treatment in Bloating Predominant Functional Bowel Disorders
This randomized, double-blind, placebo-controlled trial will evaluate the effects of a 14-day course of rifaximin on bloating symptoms, gut microbiota, microbial metabolites, and intestinal gases in adults with Rome V irritable…
- Conditions
- Bloating, Rifaximin, Functional Bowel Disorder, Irritable Bowel Syndrome
- Trial name
- NCT07522255
- Testing
- Rifaximin (drug)
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Demyelinating Disease
Pharmacological Recruitment of Endogenous Neural Precursors to Promote Pediatric White Matter Repair: Establishing Correlations Between Visual Outcomes, Saccadic Function and MEG Oscillations in Children With Demyelinating Disorders in Comparison to Healthy Control Children
The neural circuits in our brains require a layer of insulation in order to transmit signals in a rapid and efficient fashion. This insulation is called White Matter and is comprised of a specific type of brain cell called an…
- Trial name
- NCT03010826
- Where
- 2 sites in Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Substance Use Disorders (SUD)
Substance-focused SBI as a Complement to Internet-based Psychiatric Treatment: RCT
Objectives: This study evaluates the efficacy of eScreen for internet psychiatry patients treated for major depressive disorder, panic anxiety and social phobia.
- Trial name
- eScreeniPsy (NCT01885026)
- Testing
- eScreen, Assessment only of alcohol and drug use., Internet-based treatment for depression or anxiety
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Karolinska Institutet
Esophageal Squamous Cell Carcinoma
Carrelizumab Combined With Concurrent Radiotherapy and Chemotherapy for Unresectable Esophageal Squamous Cell Carcinoma
This study is a randomized, double-blind, placebo-controlled, multicenter phase III clinical study to evaluate the efficacy and safety of carrelizumab plus concurrent chemoradiotherapy compared with placebo plus concurrent…
- Trial name
- NCT06048926
- Testing
- Carrelizumab, Paclitaxel injection, Cisplatin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
ADHD
Efficacy and Safety of SPD503 in Combination With Psychostimulants
The purpose of this study is to assess the efficacy and safety of SPD503 in subjects with ADHD when co-administered with psychostimulants in children and adolescents aged 6-17 years with a diagnosis of ADHD with a sub-optimal…
- Trial name
- NCT00734578
- Testing
- SPD503-AM, SPD503-PM
- Where
- 61 sites in United States
- Volunteers
- 461 people
- Sponsor
- Shire
Osteoporosis, Multiple Sclerosis
Zoledronic Acid in MS-patients With Osteoporosis
This study is designed to evaluate the efficacy and safety of zoledronic acid 5 mg intravenous (i.v.) relative to placebo in Multiple Sclerosis (MS) patients with osteoporosis and to support the optimal use of zoledronic acid for…
- Trial name
- EXALT (NCT01166178)
- Testing
- Zoledronic Acid, Calcium and Vitamin D combination
- Where
- 15 sites in Germany
- Volunteers
- 29 people
- Sponsor
- Novartis
Chronic, Intractable Pain of the Trunk and/or Lower Limbs
Evaluating Anatomic Versus Targeted Lead Placement for Burst Stimulation Therapy During the Trial
Prospective, multi-center, randomized, single blind study
- Trial name
- DELIVERY (NCT03277378)
- Testing
- lead placement followed by BurstDR stimulation
- Where
- 25 sites in United States, Australia and 5 more
- Volunteers
- 270 people
- Sponsor
- Abbott Medical Devices
Pancreatic Cancer
The Efficacy and Safety of K-001 in the Treatment of Advanced Pancreatic Cancer
No Standard therapy has been approved for third-line therapy of advanced pancreatic cancer. K001 is peptidoglycan prepared from the marine microorganism, with an anti-tumor activity.
- Trial name
- NCT04183478
- Testing
- K-001
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Bacterial Disease Carrier, Cystic Fibrosis
A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa
This is a phase 1b/2 study of a single dose of intravenous (IV) bacteriophage in males and non-pregnant females, at least 18 years old, diagnosed with Cystic Fibrosis (CF).
- Trial name
- NCT05453578
- Testing
- WRAIR-PAM-CF1
- Where
- 19 sites in United States
- Volunteers
- 73 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity, Hypertension
Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management
The purpose of this study is to investigate the effect of providing healthy foods and nutrition education on participants' body weight, blood pressure, and average blood sugar level.
- Conditions
- Obesity, Hypertension, Pre-diabetes, Type 2 Diabetes
- Trial name
- NCT05174078
- Testing
- Medically-tailored meals, Produce box and recipes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Cleveland Clinic Akron General
Type 2 Diabetes Mellitus, Elderly
Phase 4 Study in the Elderly Patients With T2DM
The study will assess the incidence of Hypoglycemia: Percent of patients presenting no hypoglycemia (confirmed events with SMBG and severe episodes) over 6 months follow up in T2DM patients treated with a DPP-4 inhibitor or…
- Trial name
- GLYCEMIA (NCT01238978)
- Testing
- Vildagliptin, "Usual Care"
- Where
- 15 sites in France
- Volunteers
- 46 people
- Sponsor
- Novartis
Periodontitis, Periodontal Bone Loss
Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects
The present study pretends to show the results of combining a modification of the Non-incised papillae surgical approach (NIPSA) attempting to improve the outcome in the treatment of teeth with advanced periodontal support loss.
- Conditions
- Periodontitis, Periodontal Bone Loss, Periodontal; Lesion
- Trial name
- NCT03997578
- Testing
- NIPSA (Non-incised papilla surgical approach), NIPSA plus connective tissue graft
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Murcia
Decompression, Surgical
A Study on the Use of Educational Programs Prior to Lumbar Spinal Surgery
This study evaluated the hypothesis that the implementation of an educational program that informs spine patients about their condition, treatment options, prioritization on the wait list, and post-operative care would improve…
- Trial name
- NCT00719485
- Testing
- Educational program
- Volunteers
- 70 people
- Sponsor
- Sunnybrook Health Sciences Centre
Emotional Disorder, Anxiety
Unified Protocol for Bariatric Surgery Candidates
The present pilot study with a multiple baseline experimental desing will verify the feasibility and clinical utility of the Unified Protocol, applied in an online group format in a mental health setting of the Spanish national…
- Conditions
- Emotional Disorder, Anxiety, Depression
- Trial name
- NCT04421443
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Jorge Javier Osma López
Diabetes Mellitus Type 2
Effects on Remission of Type 2 Diabetes Mellitus Following Gastric Bypass Alone vs Gastric Bypass Combined With Truncal Vagotomy
This randomized, triple-blind clinical trial investigates whether adding truncal vagotomy to Roux-en-Y gastric bypass (RYGB) enhances remission of type 2 diabetes mellitus (T2DM) in patients with obesity.
- Trial name
- VagusSx (NCT07278115)
- Testing
- Roux-en-Y Gastric Bypass plus Truncal Vagotomy, Roux-en-Y Gastric Bypass
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- University Research Institute for the Study of Genetic & Malignant Disorders in Childhood
Stress, Psychological, Stress Disorders, Traumatic
Intergenerational Transmission of Traumatic Stress
Millions of U.S. parents have experienced trauma, putting them at risk for maladaptive parenting practices, which then confer vulnerabilities to their children.
- Conditions
- Stress, Psychological, Stress Disorders, Traumatic, Emotion Regulation, Behavior, Child
- Trial name
- NCT05264415
- Testing
- Families OverComing Under Stress (FOCUS) for Early Childhood (FOCUS-EC), Parenting Education Website
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
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