Clinical trials: CONTROL Condition
Mammaplasty, Cicatrix
RN1001(Avotermin) in Scar Improvement Following Breast Augmentation
This will be a multi-centre, double-blind, within-subject, placebo controlled randomised trial in female subjects. All subjects will undergo bilateral breast augmentation surgery.
- Trial name
- NCT00436449
- Testing
- Avotermin
- Where
- 7 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Renovo
HIV Infections
A Phase I Pharmacokinetics and Safety Study of Two Dapivirine Intravaginal Gels
IPM 012 is a double-blind, randomized, placebo-controlled phase I study conducted at one research center in Belgium among 36 healthy, HIV-negative women of 18-40 years of age, randomized in a 1:1:1 ratio to assess plasma, vaginal…
- Trial name
- NCT00613249
- Testing
- Dapivirine Gel 4750, 0.05%, 2.5g, Dapivirine Gel 4789, 0.05%, 2.5g
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Atrial Fibrillation (Permanent), Atrial Fibrillation (AF)
Atrial Fibrillation: In Search for the Optimal Target for Rate Control
A rate control strategy is commonly adopted in the management of patients with Atrial Fibrillation (AF). Controversies remain as regards to what constitutes the optimal target of rate control.
- Trial name
- STRICT-4-FUN (NCT07135258)
- Testing
- Ivabradine + Usual Care
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Progressive Relaxation Exercise, Hernia
Effects of Relaxation Exercises on Fear of Movement, Pain, and Quality of Life in Lumbar Disc Herniation Patients
This study evaluates whether progressive relaxation exercises can reduce fear of movement, pain, and improve quality of life in patients with lumbar disc herniation.
- Conditions
- Progressive Relaxation Exercise, Hernia, Pain, Kinesiophobia
- Trial name
- NCT07419958
- Testing
- progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Hasan Kalyoncu University
Social Anxiety Disorder
Feasibility Study of PH94B Nasal Spray for Acute Treatment of Social Anxiety Disorder (SAD)
The purpose of the study is to determine whether the PH94B nasal spray is effective for Acute Treatment of the symptoms of Social Anxiety Disorder (SAD) in adult men and women.
- Trial name
- NCT02622958
- Testing
- PH94B
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Muscular Dystrophies, Muscular Dystrophy, Duchenne
A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
HOPE-3 is a two cohort, Phase 3, multi-center, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of a cell therapy called deramiocel (CAP-1002) in study participants with Duchenne…
- Conditions
- Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- HOPE-3 (NCT05126758)
- Testing
- Deramiocel (CAP-1002)
- Where
- 20 sites in United States
- Volunteers
- 106 people
- Sponsor
- Capricor Inc.
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Posttraumatic Stress Disorder (PTSD)
Brain Imaging of Psychotherapy for Posttraumatic Stress Disorder (PTSD)
The investigators are seeking people who have been exposed to a traumatic event in the past and have symptoms of posttraumatic stress disorder (PTSD) currently.
- Trial name
- NCT01507948
- Testing
- Prolonged exposure
- Where
- 2 sites in United States
- Volunteers
- 94 people
- Sponsor
- Stanford University
Obsessive Compulsive Disorder
Genetics of Obsessive-Compulsive Disorder
The purpose of this study is to identify genes that affect susceptibility to obsessive-compulsive disorder (OCD). By identifying genes that increase or decrease the risk of OCD, researchers can better understand how the condition…
- Trial name
- NCT00001548
- Where
- United States
- Volunteers
- 1,067 people
- Sponsor
- National Institute of Mental Health (NIMH)
Postural Orthostatic Tachycardia Syndrome (POTS), Dysautonomia
Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial
The goal of this clinical trial is to learn whether guanfacine or cromolyn sodium can improve symptoms and physical functioning in adults with Postural Orthostatic Tachycardia Syndrome (POTS).
- Conditions
- Postural Orthostatic Tachycardia Syndrome (POTS), Dysautonomia, Orthostatic Intolerance, Autonomic Nervous System Diseases
- Trial name
- DBPOTS (NCT07757555)
- Testing
- Guanfacine (GFC), Cromolyn Sodium
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University
Geographic Atrophy
A Study of NGM621 in Participants With Geographic Atrophy
This is a multi-center evaluation of NGM621 in a randomized, double-masked, sham-controlled study in participants with Geographic Atrophy secondary to Age-related Macular Degeneration.
- Trial name
- CATALINA (NCT04465955)
- Testing
- NGM621
- Where
- 65 sites in United States
- Volunteers
- 320 people
- Sponsor
- NGM Biopharmaceuticals, Inc
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injections for Post-Operative Pain Following Colorectal Surgery
The purpose of this Phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, placebo-controlled study.
- Trial name
- NCT02489526
- Testing
- VVZ-149 Injections
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Vivozon, Inc.
Abortion, Induced
Cervical Priming Before Dilation & Evacuation
The purpose of this study is to compare the efficacy of buccal misoprostol cervical priming to laminaria priming among women undergoing D\&E at 13-20 weeks gestation in the Western Cape Province, South Africa
- Trial name
- NCT01597726
- Testing
- Misoprostol, Laminaria
- Where
- South Africa
- Volunteers
- 159 people
- Sponsor
- Ibis Reproductive Health
Polymyositis, Dermatomyositis
A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis
This was a Phase 2 randomized, double-blind, placebo-controlled, crossover, multicenter study to evaluate the safety, tolerability, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of treatment with KZR-616 in patients…
- Trial name
- PRESIDIO (NCT04033926)
- Testing
- KZR-616
- Where
- 14 sites in United States, Czechia and 1 more
- Volunteers
- 25 people
- Sponsor
- Kezar Life Sciences, Inc.
Parkinson Disease
Treadmill Training in People With Parkinson's Disease
The study will explore if coupling speed and cadence during treadmill training elicit more benefits than controlling speed alone in individuals with Parkinson's disease.
- Trial name
- NCT05239026
- Testing
- Advanced treadmill walking, Traditional treadmill walking
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Georgia State University
PARKINSON DISEASE (Disorder)
Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Counteract Dopaminergic Desensitization and Neuropsychiatric Complications in Parkinson's Disease
This study is a Phase III multicentric randomized controlled trial with parallel group design and waiting list in patients that have an indication to undergo intestinal L-Dopa + entacapone (Lecigon®) under the existing indication…
- Trial name
- INITIATE-LECIG (NCT07151378)
- Testing
- LECIG (levodopa, carbidopa, entacapone intestinal gel), Best oral medication
- Where
- 7 sites in Germany
- Volunteers
- 150 people
- Sponsor
- University Hospital Tuebingen
Hypercholesterolemia
Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.
The purpose of the study is to determine the efficacy of lapaquistat acetate, once daily (QD), taken with simvastatin on cholesterol levels in subjects with primary dyslipidemia
- Trial name
- NCT00256178
- Testing
- Lapaquistat acetate and simvastatin, Simvastatin
- Where
- 53 sites in Czechia, Estonia and 5 more
- Volunteers
- 411 people
- Sponsor
- Takeda
Substance Abuse, Cognitive Dysfunction
Aerobic Exercise for Cognitive Functioning in Patients With Substance Use Disorder
Impaired cognitive function is common among patients with substance use disorder (SUD). This is particularly related to executive functions (EF), which includes abilities like decision-making, consequence analysis and…
- Trial name
- SO_CogEx (NCT05324085)
- Testing
- High-intensity interval training, Treatment as usual
- Where
- Norway
- Volunteers
- 84 people
- Sponsor
- St. Olavs Hospital
Obesity
ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
The purpose of this clinical research trial is to study safety and effectiveness of the TransPyloric Shuttle System (TPSS) for weight reduction in patients who are considered medically obese.
- Trial name
- NCT02518685
- Testing
- TransPyloric Shuttle, Lifestyle Counseling
- Where
- 9 sites in United States
- Volunteers
- 302 people
- Sponsor
- BaroNova, Inc.
Papillomavirus Infections
A Clinical Study of V503 in Chinese Females Who Have Previously Received a Bivalent Human Papillomavirus (HPV) Vaccine (V503-108)
Researchers want to learn if V503 (also called the 9-valent human papillomavirus [9vHPV] vaccine, recombinant) can induce an immune response to HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 in Chinese females who previously…
- Trial name
- NCT07785843
- Testing
- V503
- Where
- China
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
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