Clinical trials: COPD
Pulmonary Disease, Chronic Obstructive, Tobacco Smoking
COPD E-cigarette Topography Training
This study is for people with chronic obstructive pulmonary disease (COPD) and who smoke. Investigators are trying to find out if training on e-cigarette use will help smokers switch to e-cigarettes.
- Trial name
- NCT05510154
- Testing
- Brief advice, Single Training, Training to Competency
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
COPD, Chronic Lung Disease
A Clinical Evaluation of the Oxitone Non-invasive Oximeter
The trial shall assess the accuracy of the Oxitone® 1000 in measuring oxygen saturation, by comparing its measurement to reference devices: non-invasive SpO2 and pulse-rate values determined by a pulse oximeter.
- Trial name
- CPOM (NCT02658045)
- Testing
- Standard Oximeter, Oxitone oximeter
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Chronic Obstructive Pulmonary Disease
Oral Supplement and Acute Resistance Exercise
This study should provide the mechanistic basis for and evaluation of a new nutritional formulation to be used alongside exercise training to improve muscle function and exercise performance by minimizing exercise induced…
- Trial name
- HMB exercise (NCT06801951)
- Testing
- acute resistance exercise with oral nutrition supplementation, stable tracer infusion
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Chronic Obstructive Pulmonary Disease (COPD
Study in Healthy Volunteers and COPD Patients to Evaluate the Efficacy and Safety of Inhaled TV46017
The primary objective of the study is to characterize the safety profile and duration of bronchodilation of a single dose of inhaled TV46017
- Trial name
- NCT02315131
- Testing
- TV46017
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
COPD, Emphysema, Asthma COPD Overlap, Emphysema
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (>15 pack years) with COPD, Emphysema, and…
- Trial name
- NCT03263130
- Testing
- As above: diagnosis: COPD, Emphysema, Asthma-COPD Overlap
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gelb, Arthur F., M.D.
Asthma, COPD
Novel Biomarkers in Chronic Airway Diseases
The purpose of this study is: To define The differences of bio-chemical phenotypes in chronic airway inflammatory diseases. To identify novel biomarkers in chronic airway inflammatory diseases as a screening, diagnostic, or…
- Trial name
- NCT00849836
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University
COPD, Asthma
A Study Into Airways Disease Case Finding and Management
Chronic Obstructive Pulmonary Disease (COPD) is a disease of the lungs which is generally caused by smoking tobacco. It is a largely preventable disease that causes severe and irreversible damage to the lungs.
- Trial name
- ASSIST (NCT03355677)
- Testing
- Case finding Clinic, At Risk Case Clinics, Usual Care
- Where
- United Kingdom
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Southampton
COVID-19, Virus Diseases
Bacillus Calmette-guérin Vaccination to Prevent COVID-19
Based on findings of the interim analysis of the ACTIVATE study showing 53% decrease of the incidence of all new infections with BCG vaccination, a new trial is designed aiming to validate if BCG can protect against COVID-19…
- Conditions
- COVID-19, Virus Diseases, Corona Virus Infection, Coronary Heart Disease
- Trial name
- ACTIVATEII (NCT04414267)
- Testing
- BCG vaccine
- Where
- 15 sites in Greece
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Hellenic Institute for the Study of Sepsis
Spirometry, Qadriceps Muscle
The Effect of Orally Administered L- Arginine on Quadriceps Strenght in Healthy Smokers
The study will investigate changes in certain locomotor parameters as early predictors of disease in smokers who are prone to develop chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04643600
- Testing
- L-Arginine, 500 Mg Oral Capsule
- Where
- Croatia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Goranka Radmilović
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking Cessation
This study will develop and experimentally test the efficiency of a neurofeedback training protocol vs. varenicline use for smoking cessation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Smoking
- Trial name
- NCT02991781
- Testing
- Biofeedback and Neurofeedback Training, Varenicline use for smoking cessation, Passive Control
- Where
- 3 sites in Bulgaria, Cyprus and 1 more
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Asthma, COPD
Blood Collection From Individuals With Lung Disease for Genetic Studies
This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung…
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- NCT00362739
- Where
- United States
- Volunteers
- 3,087 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
COPD, Healthy
The Effectiveness of Dual-task Exercises in Individuals With COPD
The goal of this clinical trial is to evaluate the effect of dual-task performance on motor and cognitive functions and to determine the effect of dual-task exercises given together with the pulmonary rehabilitation program on…
- Trial name
- NCT05930158
- Testing
- Dual Task Exercises, Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Marmara University
COPD
Human Safety of Capsaicin Inhalation Challenge Testing for Young and Older Men
In 2004, the investigators initiated a human Capsaicin inhalation experiment under an Investigational New Drug (IND) protocol approved by the FDA (IND 69,642) and the subject safety procedures instituted and approved by the…
- Trial name
- Capsaicin (NCT01621685)
- Testing
- biological/vaccine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Respiration Disorders
To Identify if a COPD Self-management App Can Safety and Appropriately Identify When Patients Are Not on the Best Medication Plan for Their COPD Symptoms and Support Their COPD Management.
Although COPD cannot be cured, managing COPD can help reduce symptoms control, slows progression of the disease, and may improve the quality of life.
- Trial name
- mySmartCOPD (NCT07797985)
- Testing
- MMH-LAB1 app
- Where
- United Kingdom
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Tracheomalacia, Tracheobronchomalacia
Tracheal Mechanics During Bronchoscopy
The main purpose of this study is use a new type of measurement to help decide what kind of therapy would help people with a collapsing windpipe or tracheomalacia.
- Trial name
- NCT00536315
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
COPD, Smoking
Defective FGFR2 Signaling in the Small Airway Basal Progenitor Cells in COPD
Early changes associated with the development of smoking-induced diseases, e.g., COPD and lung cancer (the two commonest causes of death in U.S.) are often characterized by abnormal airway epithelial differentiation.
- Conditions
- COPD, Smoking, Lung Disorder
- Trial name
- NCT02341326
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Chronic Obstructive Pulmonary Disease (COPD)
Single Dose Lipopolysaccharide (LPS) Study In Healthy Volunteers
A single dose study with the inhaled anti-inflammatory agent PF-03715455 to establish if it has anti-inflammatory activity following a challenge with LPS.
- Trial name
- NCT01314885
- Testing
- PF-03715455, PH-797804
- Where
- 2 sites in United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
Repeat Dose Study in Male Healthy Volunteer Smokers
This is a 4 to 6 week study to look at the safety and PK profile of SB656933 in healthy male smokers
- Trial name
- NCT00615576
- Testing
- SB-656933
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Exhaled Breathing Condensate (EBC) Features and Lung Function Decline in Chinese Adults
Chronic obstructive lung disease (COPD) is a worldwide leading and still increasing cause of chronic morbidity and mortality. The important issue of COPD is its delayed diagnosis.
- Trial name
- NCT02037828
- Where
- China
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
COPD, Asthma
AirSonea Wheeze Detection Study
The purpose of this study is to determine if the AirSonea device provides an objective assessment of breath sounds for the presence of wheeze in both medical and home environments.
- Trial name
- NCT01927172
- Testing
- AirSonea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- iSonea