Clinical trials: COPD
HIV, Cardiovascular Disease
Ugandan Non-Communicable Diseases and Aging Cohort
Longitudinal cohort study of older-aged people living with HIV infection in southwestern Uganda and age and gender-matched HIV uninfected controls with the primary aim of measuring the epidemiology of cardiovascular and pulmonary…
- Conditions
- HIV, Cardiovascular Disease, Chronic Obstructive Pulmonary Disease, Atherosclerosis
- Trial name
- UGANDAC (NCT02445079)
- Testing
- This is an observational study only
- Where
- Uganda
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lung Diseases, Obstructive
Cigarette Smoke Nasal and Whole Blood Challenge in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This is a clinical research study to assess whether after exhaling a single cigarette smoke through the nose there are changes in the inflammatory cells and proteins of nasal secretions.
- Trial name
- NCT00159341
- Testing
- Nasal lavage, Nasal filter paper, Blood sampling
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stable COPD Patients
Study on the Mechanism of Yifei Moxibustion Improving Immune Function in COPD Based on Plasma Exosome miRNAs
This study adopted a randomized controlled design, enrolling 90 patients and 30 healthy volunteers. The patients were randomly divided into the Yifei Moxibustion group, the conventional Western medicine treatment group, and the…
- Trial name
- NCT07131020
- Testing
- Yifei moxibustion, Conventional Western medicine treatment, TCM syndrome differentiation treatment
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henan University of Traditional Chinese Medicine
Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Patients With Acute Respiratory Distress Syndrome
Registry on the EXperience of Extracorporeal CO2 Removal in Intensive Care Units
Investigators will aim to conduct an observational study in order to assess very thoroughly all patients implanted by Extracorporeal carbon dioxide removal (ECCO2R) in 10 critical care units of Paris and its surburb (APHP…
- Trial name
- REXECOR (NCT02965079)
- Testing
- ECCO2R
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rexecor
Anesthesia
The Effect of Sevofluorane on Wash-out Time in COPD
COPD (Chronic obstructive disease ) is a condition of respiratory system failure seen occasionally in elderly patients of society. Sevofluorane is a safe, volatile anesthetic used considerably widely all over the world.
- Trial name
- washout (NCT02209883)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Chronic Obstructive Pulmonary Disease
Educational Intervention for Managing Inhalers in Chronic Obstructive Pulmonary Disease (COPD) Patients
Given the importance of the correct use of inhalers by patients with Chronic Obstructive Pulmonary Disease (COPD) for the appropriate treatment of the disease, the self-care programme which will be assessed will consist of an…
- Trial name
- NCT01380405
- Testing
- education intervention
- Where
- Spain
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Chronic Obstructive Pulmonary Disease (COPD)
TD-4208 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects
The purpose of this study is to evaluate the absorption, distribution, metabolism and excretion of an investigational medication used to treat chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02772159
- Testing
- TD-4208
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mylan Inc.
Community Health Nursing Education, Chronic Obstructive Pulmonary Disease
Virtual Reality Cave vs. Simulated Home for Community Nursing Education: A Crossover Trial Comparing Student Competence, Confidence, and Satisfaction
Background and Purpose Community health nursing is essential for providing healthcare to individuals in home and neighborhood settings.
- Conditions
- Community Health Nursing Education, Chronic Obstructive Pulmonary Disease, Pulmonary Tuberculosis
- Trial name
- NCT07595588
- Testing
- VR CAVE Immersive Simulation for Community Health Nursing Education, Traditional Simulated Home Environment for Community Health Nursing Training
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease (COPD)
A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This study is a randomized, double-Blind, placebo-controlled, Single- and Multiple-ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics and Clinical Activity of BBT002 in…
- Trial name
- NCT07288554
- Testing
- BBT002
- Where
- 11 sites in China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Bambusa Therapeutics
COPD
The Prevalence of Chronic Pain in COPD and Its Clinical Implications
This study explores the prevalence of chronic pain in individuals with COPD compared to healthy controls and examines the clinical implications of pain on symptoms associated with COPD, psychological effect and physical activity.
- Trial name
- NCT05366946
- Testing
- Prevalence study
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- West Park Healthcare Centre
Asthma
Study to Evaluate the Pharmacokinetic Profile of Salbutamol Delivered by Unit Dose Dry Powder Inhaler (UD-DPI) Compared to the Diskus and Metered Dose Inhaler (MDI) in Healthy Volunteers.
This is an open-label, two part, six period- cross over, randomised, single dose, single centre study in healthy subjects. This is the first clinical study for the UD-DPI. This study is divided into two parts.
- Trial name
- NCT01984086
- Testing
- Salbutamol Sulphate 150mcg UD-DPI Blister(1.6% blend), Salbutamol Sulphate 200mcg UD-DPI Blister(1.6% blend), Salbutamol Sulphate 250mcg UD-DPI Blister(1.6% blend)
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COPD, Microbial Colonization
Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD)
Some components of the diet could promote the growth of certain bacterial strains present in the intestine, which are closely associated with benefits for host health.
- Conditions
- COPD, Microbial Colonization, Respiratory Tract Disease
- Trial name
- NCT05126654
- Testing
- Partially Hydrolyzed Guar Gum (PHGG)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Chronic Obstructive Pulmonary Disease (COPD), Asthma
A Study to Evaluate the Disposition of Drug in Body and Safety After Administration of Single Inhaled Doses of Drugs Abediterol and AZD7594 Administered Alone, in Fixed Dose Combination and in Free Combination Using the Dry Powder Inhaler in Healthy Male Participants
AZD7594 is a non steroidal, potent and selective modulator of the glucocorticoid receptor (GR) under development for once daily inhaled treatment of chronic obstructive pulmonary disease (COPD) and asthma.
- Trial name
- NCT02967159
- Testing
- Abediterol, AZD7594, AZD7594/abediterol
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Low Back Pain, Chronic Obstructive Pulmonary Disease
Nonspecific Low Back Pain in Association With Chronic Obstructive Pulmonary Disease
Introduction. Nonspecific low back pain (NSLBP) is a very prevalent medical condition, especially in subjects with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT03227523
- Where
- Spain
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Delirium, Copd
ABCDEF Bundle to Prevent Delirium for COPD Patients
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic respiratory symptoms, resulting from abnormalities in the bronchi…
- Conditions
- Delirium, Copd, Nurse's Role
- Trial name
- COPD (NCT06974318)
- Testing
- ABCDEF Bundle to Prevent Delirium, Standard Care to Prevent Delirium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
This study will assess the pharmacodynamics, pharmacokinetics, safety and tolerability of BYM338 in patients with COPD and cachexia. The primary outcome will be a change in thigh muscle volume compared to placebo.
- Trial name
- NCT01669174
- Testing
- BYM338
- Where
- 9 sites in United States, Netherlands and 1 more
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Vascular Impairment in Chronic Obstructive Pulmonary Disease (COPD) Assessed by MRI
Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent pulmonary disease providing major morbidity and mortality. Bronchial obstruction is the cornerstone in assessment of the disease whereas associated pulmonary…
- Trial name
- PulmoVasc (NCT04126616)
- Testing
- chest Magnetic Resonance Imaging (MRI) using Gadolinium-based contrast agent
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Critical Illness, Chronic Obstructive Lung Disease
Advance Care Planning Evaluation in Hospitalized Elderly Patients
The purpose of the study is to inform decision-makers of the best strategies to implement advanced care planning (ACP). An advanced care plan (ACP) is a verbal or written instruction describing what kind of care an individual…
- Conditions
- Critical Illness, Chronic Obstructive Lung Disease, Congestive Heart Failure, Cirrhosis
- Trial name
- ACCEPT (NCT01362855)
- Where
- 9 sites in Canada
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Daren K. Heyland
Smoking, COPD
Canadian Cohort on the Origin and Progression of Airway Disease: Physiology Platform
The Canadian Respiratory Research Network (CRRN) has recently been established to study the origins and evolution of airways disease in the population.
- Trial name
- NCT02153684
- Where
- 3 sites in Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Dr. Denis O'Donnell
COPD, IPF
Functional MR Lung Imaging Using Hyperpolarised 129Xe
The aim of this study is to investigate the potential value of a novel imaging technique (hyperpolarized 129Xe lung imaging) in the diagnosis and assessment of lung disease in patients with COPD and IPF.
- Trial name
- NCT02976935
- Testing
- hyperpolarised 129 Xenon
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Nottingham