Clinical trials: COPD
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Exercise Ventilatory Support Pressure on Endurance in Patients With Severe Chronic Obstructive Pulmonary Disease - AVE-BPCO
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by progressive obstruction of the airways.
- Trial name
- AVE-BPCO (NCT07125989)
- Testing
- non-invasive ventilation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
COPD
Analyse the Correlation Between sEMG and EMGdi
The most significant pathophysiology change of COPD patients is persistent incompletely reversible airflow obstruction and increased lung volume. As a result, the work of breathing(WB) and neural respiratory drive (NRD)increased.
- Trial name
- NCT03268616
- Testing
- inspiratory threshold load device and NPPV
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Chronic Obstructive Pulmonary Disease
Effect of Extremity Exercise in COPD
Objective: is to find out the effect of unsupported upper extremity exercise versus lower extremity exercise on dyspnea and lung function Methodology: Sample and design: 60 patients with Randomized study design will be included…
- Trial name
- NCT04076085
- Testing
- exercise
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Khalid University
Severe COPD
Advance Care Planning Individualised Approach and Research Projec
The study will investigate the effect of a palliative approach in the out-patient management of patients with COPD.
- Trial name
- AIR (NCT03915743)
- Testing
- palliative care
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Herlev and Gentofte Hospital
Chronic Obstructive Pulmonary Disease
The Effect of Distractive Auditory Stimuli (Music) on Dyspnea and Anxiety During Exercise in Adults With Chronic Respiratory Diseases
The objective of this study is to look at the effects of distractive auditory stimuli (DAS) on reducing dyspnea intensity and related anxiety and increasing exercise tolerance.
- Trial name
- NCT02955108
- Testing
- Distractive Auditory Stimuli, No Distractive Auditory Stimuli
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Chronic Obstructive Pulmonary Disease
A Crossover Study in the Treatment of Patients With COPD
The purpose of this study is to compare the efficacy of Formoterol Fumarate Inhalation Solution (FFIS) 20 mcg BID to Combivent® Inhalation Aerosol [2 inhalations from metered dose inhaler (MDI)of 18 mcg ipratropium bromide and…
- Trial name
- NCT00462540
- Testing
- Formoterol Fumurate inhalation solution 20 mcg, Ipratropium bromide 18 mcg and albuterol sulfate 103 mcg
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dey
Chronic Obstructive Pulmonary Disease
Effects of Tiotropium on Walking Capacity in Patients With COPD
This study was designed to test the following hypothesis: A) The acute and long-term (3 weeks) bronchodilator-induced changes in exercise tolerance and in the physiological response during the endurance shuttle walk will be…
- Trial name
- NCT01307189
- Testing
- Tiotropium
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Laval University
Copd, Asthma
Respiratory Disorders Non-invasive Monitoring of Work of Breathing in Outpatients
This study will test the accuracy of an investigational, non-invasive device for measuring heart rate and respiratory rate. The device emits radiowaves that allows it to pick up subtle changes in a person's chest wall, which…
- Conditions
- Copd, Asthma, Respiratory Effort, Contactless Vital Sign Monitoring
- Trial name
- NCT04003415
- Testing
- Investigational Device: Contactless heart rate and respiratory rate monitor, Heart Rate (EKG) Monitor, Respiratory rate Monitor
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Chronic Obstructive Pulmonary Disease (COPD)
Feasibility Study of Telerehabilitation for People with Chronic Obstructive Pulmonary Disease in Nuuk
Chronic obstructive pulmonary disease, or COPD, is a major global health issue. It can make people ill, impact their quality of life, and increase their use of healthcare services.
- Trial name
- NCT06660589
- Volunteers
- 10 people
- Sponsor
- Steno Diabetes Center Greenland
Chronic Obstructive Pulmonary Disease, COPD
OPUS Study: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-111)
The purpose of this study is to determine whether roflumilast is effective in the treatment of exacerbations in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00076089
- Testing
- Roflumilast
- Where
- 40 sites in United States, Canada and 4 more
- Volunteers
- 1,100 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
A Study to Evaluate the Efficacy of MEDI8968 in Chronic Obstructive Pulmonary Disease
The purpose of this study is to evaluate the effect of MEDI8968 on the rate of moderate or severe acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in adult subjects with symptomatic, moderate to very severe…
- Trial name
- SPRING (NCT01448850)
- Testing
- MEDI8968 600 mg IV, 300 mg SC
- Where
- 60 sites in United States, Bulgaria and 8 more
- Volunteers
- 464 people
- Sponsor
- MedImmune LLC
Chronic Obstructive Pulmonary Disease
COPD Assessment and Management Bundle Versus Usual Care
Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory (lung) disease that makes it harder to breathe over time.
- Trial name
- NCT01833026
- Testing
- Spirometry test, Levalbuterol
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Illinois at Chicago
COPD (Chronic Obstructive Pulmonary Disease), Caregiver
Validation of the French Version of the QASCI in Caregivers of Patients With COPD
This study aims to validate the French version of the QASCI questionnaire, initially written and validated in Portuguese language by Hipolito et al., to assess caregiving burden in chronic obstructive pulmonary disease (COPD).
- Trial name
- VALQASCI (NCT06652204)
- Testing
- questionnaire
- Where
- 2 sites in France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Chronic Obstructive Pulmonary Disease
High Frequency Chest Wall Oscillation in Chronic Obstructive Pulmonary Disease (COPD)
Patients with Chronic obstructive pulmonary disease (COPD) tend to have cough, excess mucus production and breathlessness as cardinal features.
- Trial name
- NCT00863616
- Testing
- HFCWO - SmartVest
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- East and North Hertfordshire NHS Trust
Chronic Obstructive Pulmonary Disease
PT003 MDI Dose Confirmation Study
The primary objective of this study is to demonstrate efficacy of PT003 MDI relative to its individual components (PT001 MDI and PT005 MDI) in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01349816
- Testing
- PT003, PT001, PT005
- Where
- 13 sites in United States
- Volunteers
- 185 people
- Sponsor
- Pearl Therapeutics, Inc.
Healthy
DBM-1152A Inhalation Solution in Healthy Volunteers
This is a single-center, randomized, double-blind, placebo-controlled Phase 1b study to evaluate the safety, tolerability, and pharmacokinetics (PK) of multiple-dose DBM-1152A inhalation solution in healthy Chinese adults.
- Trial name
- NCT07439419
- Testing
- DBM-1152A
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd
Chronic Obstructive Pulmonary Disease
Characteristics That Identify Exacerbation Risk Following Colds in COPD Patients
Respiratory virus infections are a common cause of COPD exacerbations and antiviral therapies have potential as treatments for exacerbations.
- Trial name
- NCT01376830
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease
Combined Effects Of Autogenic Drainage and Segmental Breathing Techniques in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is one of the most common life threatening disease affecting population. It is a preventable and treatable lung disease.
- Trial name
- NCT06480422
- Testing
- Segmental breathing technique, autogenic drainage
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Infection, Heart Failure
Prediction of 30-Day Readmission Using Machine Learning
This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict…
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04849312
- Where
- 2 sites in United States
- Volunteers
- 372 people
- Sponsor
- Brigham and Women's Hospital
COPD Exacerbation, Physical Activity
Changes in Microcirculation and Functional Status During Exacerbation of COPD
This study investigates the influence of acute exacerbation of chronic obstructive pulmonary disease (COPD) on retinal microcirculation, on functional status and also investigates the prognostic value of retinal vessel caliber…
- Conditions
- COPD Exacerbation, Physical Activity, Retinal Vascular
- Trial name
- COPD-EX (NCT03250000)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Hasselt University