Clinical trials: COPD, completed
Chronic Obstructive Pulmonary Disease, Aging
Fiber Metabolism in Chronic Obstructive Pulmonary Disease
The impact of fiber intake on short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare changes in SCFA metabolism after inulin vs.
- Trial name
- NCT04459156
- Testing
- Fiber Inulin
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pulmonary Disease, Chronic Obstructive
Study In Subjects With COPD (Chronic Obstructive Pulmonary Disease)
This study was designed to determine if the investigational drug is effective and safe in individuals with COPD (chronic pulmonary disease)
- Trial name
- NCT00103922
- Testing
- cilomilast
- Where
- 115 sites in United States
- Volunteers
- 600 people
- Sponsor
- GlaxoSmithKline
COPD, Asthma
Efficacy of Education Programs in Patients With Chronic Airway Diseases
The objective of this study is to determine whether the systematic education on air way disease and inhalers in outpatient settings contributes to improve the quality of life.
- Trial name
- NCT02827929
- Testing
- Education
- Where
- South Korea
- Volunteers
- 285 people
- Sponsor
- Konkuk University Medical Center
Chronic Obstructive Pulmonary Disease
Effectiveness of Incorporating Tai Chi in Pulmonary Rehabilitation Program for Chronic Obstructive Pulmonary Disease Patients in Primary Health Care
The purpose of this study was to compare the self-efficacy and quality of life parameters of Chronic Obstructive Pulmonary Disease(COPD)patients who underwent pulmonary rehabilitation with and without Tai Chi elements…
- Trial name
- COPD (NCT01259245)
- Testing
- Tai chi + PRP, PRP
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Kwong Wah Hospital
COPD, Emphysema
Regulation of Inflammatory Mediators in Chronic Obstructive Pulmonary Disease
The aim of this study is to investigate the mechanisms whereby lung function is decreased in COPD. The hypothesis is that in diseases such as COPD, inflammatory cells including neutrophils, macrophages and lymphocytes migrate to…
- Trial name
- NCT00147095
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Dyspnea
The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in COPD
Chronic Obstructive Pulmonary Disease (COPD) is a lung disorder commonly caused by smoking, which makes breathing more difficult.
- Trial name
- iNO (NCT03679312)
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Weaning Failure, COPD Exacerbation
Comparison of Two Ventilator Mode During the Night: New Strategy of Mechanical Ventilation Weaning
The purpose of the study is to compare pressure controlled continuous mandatory ventilation versus pressure support ventilation during the night for weaning to mechanical ventilation in chronic obstructive pulmonary disease…
- Trial name
- REVENTIL (NCT01573481)
- Testing
- pressure support ventilation, Pressure controlled ventilation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Healthy Volunteers
Assessment of Exercise Capacity in Virtual Reality
The 20th century brought a dynamic development of new technologies, including virtual reality (VR). VR is an artificial image generated by IT technologies.
- Trial name
- NCT04197024
- Testing
- Exercise capacity test, Exercise capacity test in virtual reality
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
COPD, Chronic Obstructive Pulmonary Disease (COPD)
Comparative Effects of Triple Inhaled Therapy With Budesonide/Glycopyrronium/Formoterol Versus Fluticasone Furoate/Umeclidinium/Vilanterol on Small Airway Disease in COPD Patients: A Randomized Crossover Study
The goal of this clinical trial is to determine if triple inhaled therapy with Budesonide/Glycopyrronium/Formoterol (BGF) and Fluticasone Furoate/Umeclidinium/Vilanterol (FUV) are effective in treating patients with stable…
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease (COPD), Small Airway Disease, Triple Therapy
- Trial name
- NCT06905483
- Testing
- Budesonide/Glycopyrronium/Formoterol (BGF), Fluticasone Furoate/Umeclidinium/Vilanterol (FUV)
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Thammasat University
COPD, Emphysema
Leukocyte Function in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this study is to investigate the mechanisms whereby leukocytes are recruited to the lung in chronic obstructive pulmonary disease (COPD) and cause tissue destruction.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- NCT00147082
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma Exacerbation, COPD Exacerbation
A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Adolescent and Adult Patients in an Emergency Department
Aim is to to demonstrate that the ResAppDx v2.0 algorithms provide an accurate diagnosis of respiratory disease in the study's clinical setting compared to a clinical adjudication committee's (CAC) diagnosis; and to establish a…
- Conditions
- Asthma Exacerbation, COPD Exacerbation, Lower Respiratory Disease, Pneumonia
- Trial name
- NCT06156462
- Testing
- ResAppDx v.20
- Where
- 3 sites in United Kingdom
- Volunteers
- 171 people
- Sponsor
- ResApp Health Limited
Chronic Obstructive Pulmonary Disease
Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD)
The main hypothesis is that persons that smoke or smoked tobacco and marihuana have worsen lung function as compared with persons that only smoke or smoked tobacco.
- Trial name
- NCT01096303
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
COPD, Home Care
FiO2 in Chronic Obstructive Pulmonary Disease (COPD) Patient Normobaric O2 Versus NIV
The purpose of this study is to compare pharyngeal FiO2 in day time with nasal normobaric O2 with inhaled FiO2 in the night time with home care ventilator NIV at the same O2 flow.
- Conditions
- COPD, Home Care, Oxygen Therapy
- Trial name
- NIVLEAKS (NCT02599246)
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Breas Medical S.A.R.L.
Chronic Obstructive Pulmonary Disease
Transcutaneous Electrical Muscle Stimulation In Chronic Obstructive Pulmonary Disease (COPD)
Transcutaneous electrical muscle stimulation (TCEMS) is well established intervention for rehabilitation of clinically stable patients with chronic obstructive pulmonary disease.
- Trial name
- NCT01226342
- Testing
- Transcutaneous electrical muscle stimulation
- Where
- Slovenia
- Volunteers
- 19 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Chronic Obstructive Pulmonary Disease
Developing Personalised Relative Physical Activity Thresholds in COPD.
The aim of this observational study is to translate the principle of individualised exercise prescription into the evaluation of daily absolute and relative intensity physical activity.
- Trial name
- IMPACT (NCT06330623)
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- University of Leicester
COPD, HIV/AIDS
High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults
This study examines an intervention to promote effective, evidence-based care and de-implement inappropriate therapies for COPD in HIV-infected (HIV+) patients.
- Trial name
- ACHIEVE (NCT03856879)
- Testing
- Proactive E-consult
- Where
- 7 sites in United States
- Volunteers
- 270 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Chronic Obstructive Pulmonary Disease (COPD), Emphysema
Home Pulmonary Rehabilitation for COPD
Regular physical activity has been found to be important in maintaining health and well-being in people with COPD. The purpose of this study is to test new technology and health coaching aimed to help people with COPD become more…
- Trial name
- NCT03480386
- Testing
- Home Based Pulmonary Rehabilitation
- Where
- 3 sites in United States
- Volunteers
- 375 people
- Sponsor
- Mayo Clinic
Chronic Obstructive Pulmonary Disease
Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation
Aerosol delivery through a ventilator is influenced by numerous factors from ventilator-related, circuit-related to device-related factors.
- Trial name
- NCT02818270
- Testing
- Salbutamol, Acetylcysteine
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung University
Chronic Obstructive Pulmonary Disease
Discharge Coordinator Intervention in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This is a single-centre randomized controlled clinical trial which will enroll COPD patients in Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage II-IV, hospitalized due to acute exacerbation.
- Trial name
- NCT01225627
- Testing
- Coordinated discharge, Control
- Where
- Slovenia
- Volunteers
- 253 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
COPD (Chronic Obstructive Pulmonary Disease)
A Phase 2 Trial of JKN24011 in COPD
A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Evaluate the Efficacy and Safety of Subcutaneous JKN24011 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT07440524
- Testing
- JKN24011
- Where
- China
- Volunteers
- 215 people
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd