Clinical trials: COPD (Chronic Obstructive Pulmonary Disease)
Pulmonary Disease, Chronic Obstructive, Exacerbation COPD
The COPD Attack Study
The goal of this observational study is to evaluate the frequency and predictors of exacerbations in COPD patient population in Uganda. The main questions it aims to answer are:- 1.
- Trial name
- COPA (NCT05779384)
- Testing
- It was an observational study
- Where
- 2 sites in Uganda
- Volunteers
- 323 people
- Sponsor
- Makerere University
COPD
Evaluation of COPD Co-Pilot
The purpose of undertaking this study is to examine the use of COPD Co-PilotTM, a COPD disease management program manufactured and operated by HGE Health Care Solutions, LLC, in COPD patients outside of the geographic base of…
- Trial name
- NCT03018847
- Testing
- COPD Co-Pilot
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- HGE Health Care Solutions, LLC
Chronic Obstructive Pulmonary Disease
Study to Investigate Daily Symptom Variability, Symptom Effects on Morning Activities of Chronic Obstructive Disease
The primary objective of this non-interventional study is to evaluate daily symptom variability in COPD patients. The secondary objectives are; to evaluate effects of COPD symptoms on the morning activities of patients, to…
- Trial name
- NCT01110564
- Where
- 19 sites in Turkey (Türkiye)
- Volunteers
- 515 people
- Sponsor
- AstraZeneca
Cancer, Chronic Obstructive Pulmonary Disease (COPD
Detection of Electrodermal Activity in Pain 2
The goal of this study is to investigate the association between self-reported pain and electrodermal activity and to create an algorithm that detects pain and provides timely alarms for rising pain levels in patients with…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease (COPD, Pain
- Trial name
- DEEP 2 (NCT06677593)
- Where
- Denmark
- Volunteers
- 37 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
COPD, Sympathetic Nervous System Diseases
Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
The project will be pursued in our respiratory, autonomic nervous system physiology laboratory (Respiratory, autonomic nervous system physiology laboratory, Department of Pneumology and Intensive Care Medicine, RWTH Aachen…
- Conditions
- COPD, Sympathetic Nervous System Diseases, Catecholamine; Overproduction
- Trial name
- SNAP-COPD (NCT04849806)
- Testing
- Assessments of the sympathetic nerve activity axis, OSA severity, Determination of PH and right HF severity
- Where
- Germany
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Chronic Obstructive Pulmonary Disease, Depression
Investigating the Impact of Mode of Administration on Item Response
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Rheumatoid Arthritis
- Trial name
- NCT00783991
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- Stony Brook University
Chronic Obstructive Pulmonary Disease
Effects of Tiotropium/Olodaterol on Cardio-pulmonary Exercise Capacity in Patients With Hyperinflated Chronic Obstructive Pulmonary Disease [ACHIEVE]
[Background] Hyperinflation caused by increased airflow limitation and emphysema change commonly accompanies dyspnea, which leads to inactivity, reducing exercise capacity, and deconditioning.
- Trial name
- NCT04994574
- Testing
- tiotropium/olodaterol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
High-Intensity vs Low-Intensity NPPV in Patients With an AECOPD: The HAPPEN Trial
To determine whether high-intensity NPPV, compared with low-intensity NPPV, could reduce the need for endotracheal intubation during hospitalization in patients with an AECOPD and hypercapnia.
- Trial name
- NCT02985918
- Testing
- High-intensity NPPV, Low-intensity NPPV
- Where
- 31 sites in China
- Volunteers
- 300 people
- Sponsor
- Beijing Chao Yang Hospital
COPD Exacerbation Acute
A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease, that causes obstructed airflow from the lungs that causes persistent obstructive airflow limitation.
- Trial name
- NCT05400369
- Testing
- Sitafloxacin, Moxifloxacin Hydrochloride
- Where
- 18 sites in China
- Volunteers
- 140 people
- Sponsor
- Daiichi Sankyo
Acute Decompensated Heart Failure, COPD Exacerbation
Use of ΔIVC for Early Diagnosis of AHF in AECOPD
Acute Heart failure (AHF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis.
- Trial name
- NCT05327374
- Testing
- calculation of the inferior vena cava collapsibility index
- Where
- 3 sites in Tunisia
- Volunteers
- 401 people
- Sponsor
- University of Monastir
COPD (Chronic Obstructive Pulmonary Disease), Quality of Life
Chronic Obstructive Pulmonary Disease, Quality of Life, COPD Assessment Test, Nepal, Dyspnea, Spirometry
Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. The study "Quality of life among people living with Chronic Obstructive Pulmonary Disease- visiting spirometry…
- Trial name
- NCT07261813
- Testing
- Evaluation of Quality of life in COPD patients
- Volunteers
- 71 people
- Sponsor
- Institute of medicine, Maharagjung medical campus
Chronic Obstructive Pulmonary Disease
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV
The purpose of this study is to determine whether different types of breathing therapies in patients with COPD III-IV decrease dyspnea and increase activity.
- Trial name
- NCT01478646
- Testing
- conventional breathing therapy, reflectory breathing therapy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Schön Klinik Berchtesgadener Land
COPD, Oxygen Therapy
Closed-loop System for Oxygen Delivery and Exercise in Chronic Obstructive Pulmonary Disease
The purpose of this study is to investigate the benefit of Closed-loop System for Oxygen Delivery (FreeO2) as compared with fixed oxygen flow during endurance shuttle walking test in patients with Chronic obstructive pulmonary…
- Conditions
- COPD, Oxygen Therapy, Hypercapnia
- Trial name
- FreeO2-rehab (NCT01575327)
- Testing
- Automated settings on the oxygen delivery device, Manual settings with FreeO2 system in collection mode
- Where
- 3 sites in France
- Volunteers
- 15 people
- Sponsor
- AGIR à Dom
Chronic Obstructive Pulmonary Disease
Enabling Independent Living by Expanding Access to Home-Based Pulmonary Rehabilitation
The purpose of this study is to test an existing home-based pulmonary rehab program with the addition of video chat and a capability of a Spanish version.
- Trial name
- NCT04479969
- Testing
- Video Chat
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Chronic Heart Failure, Pulmonary Disorder, Chronic Obstructive
Method To Measure Protein Digestion & Absorption
The aim of the present study is to validate a new method in healthy volunteers and those diagnosed with COPD and CHF that is able to measure protein digestion and absorption simultaneously.
- Trial name
- NCT02065141
- Testing
- sip feeding with stable isotope infusion
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Pulmonary Disease, Chronic Obstructive
Digihaler in Chronic Obstructive Pulmonary Disease (COPD)
This is a multi-center 3-month study to determine the variation in ProAir Digihaler metrics [peak inspiratory flow (PIF), inhalation volume, number of inhalation events] amongst COPD patients in the ambulatory setting.
- Trial name
- NCT05241288
- Testing
- Albuterol eMDPI DS
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- University of North Carolina, Chapel Hill
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether there is a statistical association between changes in sputum serial levels of two cytokines, interleukin (IL)-17 and IL-6, during the treatment course of a severe acute…
- Trial name
- NCT00281242
- Testing
- blood draw
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Michigan
Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Does tiotropium effect the cough reflex in patients with COPD and chronic bronchitis.
- Trial name
- NCT00870896
- Testing
- Tiotropium
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- ThomasTruncale
Pulmonary Disease, Chronic Obstructive, Lung Diseases
A Study To Investigate The Safety, Toleration And Efficacy of PF00610355 In Chronic Obstructive Pulmonary Disease (COPD) Patients.
To assess the effects and safety of PF-00610355 on patients with chronic obstructive lung disease (COPD)
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- A7881013 (NCT00808288)
- Testing
- PF-00610355, PF - 00610355, PF- 00610355
- Where
- 75 sites in United States, Argentina and 10 more
- Volunteers
- 405 people
- Sponsor
- Pfizer
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.