Clinical trials: COPD Acute Exacerbation
COPD, COPD Exacerbation Acute
ProAir Digihaler in COPD Disease Management: A Real World Study
A pilot study to explore the utilization of the TEVA ProAir Digihaler rescue medication use and inhalation parameters to identify disease deterioration to help in the management of COPD patients in clinical practice.
- Trial name
- NCT04821869
- Testing
- ProAir Digihaler, Digihaler
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Pulmonary Research Institute of Southeast Michigan
COPD Received PR, Elderly (People Aged 65 or More)
Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD
The study aimed to identify the effect of early pulmonary rehabilitation in elderly patients with Acute exacerbation (AE) of COPD (AECOPD) in exercise tolerance, dyspnea, sleep quality, fatigue, and time to discharge from…
- Conditions
- COPD Received PR, Elderly (People Aged 65 or More), COPD, COPD Acute Exacerbation
- Trial name
- NCT07020182
- Testing
- physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Exacerbation Copd, Acute Respiratory Distress
High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease
Chronic obstructive lung disease is a disabling disease that affects people usually after several years of smoke tobacco exposure and affects millions of patients worldwide.
- Conditions
- Exacerbation Copd, Acute Respiratory Distress, Acute Hypercapnic Respiratory Failure
- Trial name
- HiFOLD (NCT03033251)
- Testing
- Non Invasive Ventilation, High Flow Oxygen Cannula 50, High Flow Oxygen Cannula 30
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
COPD Exacerbation Acute
The Use of Medical Devices to Monitor Chronic Obstructive Pulmonary Disease Patients Study BREATH-TRACHER 1
The proposed study will explore whether remote monitoring of a COPD patient can be undertaken using a wearable medical device.
- Trial name
- BREATH-TRACHER (NCT06419036)
- Testing
- Pneumowave DC
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Strathclyde
COPD Exacerbation Acute
The Use of Medical Devices to Monitor Chronic Obstructive Pulmonary Disease Patients Study BREATH-TRACHER 2
The proposed study will explore whether remote monitoring of a COPD patient can be undertaken using a wearable medical device.
- Trial name
- BREATH-TRACHER (NCT06419062)
- Testing
- Frontier X2
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Strathclyde
COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD
Survey on NIV Settings in the Intensive Care Unit for Acute Exacerbation of COPD
Introduction Chronic obstructive pulmonary disease (COPD) is a common condition and the fourth leading cause of death worldwide.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD, Hypercapnic Respiratory Failure, COPD
- Trial name
- NIV-ICU (NCT06888180)
- Testing
- Non interventional study
- Volunteers
- 976 people
- Sponsor
- University Hospital, Caen
Acute Exacerbation of COPD
Copd Exacerbation and Pulmonary Hypertension Trial
This trial will investigate whether patiens admitted with an acute exacerbation of chronic obstructive lung disease and pulmonary hypertension will benefit from a targeted pharmacological treatment.
- Trial name
- CODEX-P (NCT04538976)
- Testing
- Sildenafil
- Where
- 5 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- Chronic Obstructive Pulmonary Disease Trial Network, Denmark
COPD Exacerbation Acute, Asthma Acute
Study on Acupuncture Treatment of Chronic Airway Diseases(Asthma and Chronic Obstructive Pulmonary Disease)
For patients in the acute phase of chronic airway diseases, on the basis of guideline-directed treatment, the experimental group was given acupuncture treatment, while the control group was given sham acupuncture treatment.
- Trial name
- NCT06869525
- Testing
- Acupuncture
- Volunteers
- 576 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Copd Exacerbation Acute, Readmission
Identification of Patients Admitted With COPD Exacerbations and Predicting Readmission Risk Using Machine Learning
Patients with Chronic Obstructive Pulmonary Disease (COPD) who are admitted to hospital are at high risk of readmission. While therapies have improved and there are evidence-based guidelines to reduce readmissions, there are…
- Conditions
- Copd Exacerbation Acute, Readmission, Machine Learning, Natural Language Processing
- Trial name
- NCT04192175
- Where
- Canada
- Volunteers
- 65,000 people
- Sponsor
- University Health Network, Toronto
COPD Exacerbation Acute
A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease, that causes obstructed airflow from the lungs that causes persistent obstructive airflow limitation.
- Trial name
- NCT05400369
- Testing
- Sitafloxacin, Moxifloxacin Hydrochloride
- Where
- 18 sites in China
- Volunteers
- 140 people
- Sponsor
- Daiichi Sankyo
COPD, COPD Exacerbation
Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide, and over 90% of COPD-related deaths occurring in low- and middle-income countries (LMICs).
- Conditions
- COPD, COPD Exacerbation, COPD Exacerbation Acute, Pollution Related Respiratory Disorder
- Trial name
- NCT03984188
- Testing
- Theophylline ER, Standard of Care Treatment
- Where
- 2 sites in Uganda
- Volunteers
- 100 people
- Sponsor
- University of Miami
Chronic Obstructive Pulmonary Disease, COPD
Predictors of Acute Exacerbation in Patients With COPD - an Observational Study
Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by respiratory problems and poor airflow with dyspnea and cough being the main symptoms.
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, COPD Exacerbation, COPD Exacerbation Acute
- Trial name
- PACE (NCT04140097)
- Testing
- Prospective monitoring of a large variety of parameters
- Where
- Germany
- Volunteers
- 355 people
- Sponsor
- Schön Klinik Berchtesgadener Land
COPD Exacerbation Acute, Nutrition Poor
Is a Collective Person-centered Dialogue Intervention for Hospitalised COPD Patients Feasible?
The aim of this mixed methods trial is to investigate the feasibility of a collective person-centred dialogue (COPE-D) intervention delivered by an interdisciplinary team for a population of patients hospitalised and diagnosed…
- Conditions
- COPD Exacerbation Acute, Nutrition Poor, Physical Inactivity, Relatives
- Trial name
- COPE-D (NCT06242301)
- Testing
- The collective person-centered dialogue intervention
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital
Acute Exacerbation of COPD, Corticosteroid
Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels
Chronic Obstructive Pulmonary Disease (COPD) is one of the top three causes of death worldwide now. Acute exacerbations (AEs) of COPD are a risk factor for lung function deterioration, poor quality of life, longer…
- Conditions
- Acute Exacerbation of COPD, Corticosteroid, Morality, Lung Diseases, Obstructive
- Trial name
- NCT05059873
- Testing
- Prednisone
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Capital Medical University
COPD Exacerbation Acute
CRP, Procalcitonin and Pro-BNP as Diagnostic and Prognostic Markers in AECOPD
Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) are one of the chief causes for admission to Emergency Department. AECOPD is a significant cause for mortality and morbidity worldwide.
- Trial name
- AECOPD (NCT06514599)
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
COPD Exacerbations, Acute Hypercapnic Respiratory Failure
HFNC vs. NIV in Acute COPD Exacerbations
The investigators investigated the efficacy and safety of High Flow Nasal Cannula (HFNC) at different flow rates compared to non-invasive ventilation (NIV) in patients presenting to the emergency department (ED) with acute…
- Conditions
- COPD Exacerbations, Acute Hypercapnic Respiratory Failure, Respiratory Failure
- Trial name
- HFNCstdy (NCT06495086)
- Testing
- NIV, HFNC-30, HFNC-50
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Haseki Training and Research Hospital
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD
Effect of Blood Flow Restriction Resistance Exercises in COPDAE In-patient Rehabilitation
This is a randomised controlled trial of the blood flow restriction resistance exercise (BFR-RE) for early rehabilitation of chronic obstructive pulmonary disease acute exacerbation (COPDAE) in the Haven of Hope Hospital.
- Trial name
- NCT04448236
- Testing
- Blood flow restriction resistance exercise
- Where
- Hong Kong
- Volunteers
- 53 people
- Sponsor
- Hospital Authority, Hong Kong
Chronic Obstructive Pulmonary Disease, Acute Exacerbation Copd
COPD Exacerbation Blood and Urine Biomarkers Study
This will be a prospective study examining serum levels of MMP-13 and alpha-1 antitrypsin as well as other biomarkers as well as urine biomarkers of smoking status and collagen degradation in the COPD patient population.
- Conditions
- Chronic Obstructive Pulmonary Disease, Acute Exacerbation Copd, Alpha-1 Anti-trypsin Deficiency
- Trial name
- NCT03823443
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Columbia University
COPD, COPD Exacerbation Acute
Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation
Chronic obstructive pulmonary disease (COPD) exacerbations are risk factors for disease progression and short-term re- hospitalizations.
- Trial name
- NCT06331416
- Testing
- Telemonitoring
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Trieste
Acute Exacerbation of COPD
Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPD
Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide, a respiratory disease characterized by chronic airflow limitation that is not completely reversible.
- Trial name
- NCT05563493
- Testing
- Treatment group, Chair-Based Exercise Training, Control group, Breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Necmettin Erbakan University