Clinical trials: COPD Patients
Chronic Obstructive Pulmonary Disease
A Study to Investigate How Safe and Well Tolerated RV568 is in Patients With Chronic Obstructive Pulmonary Disease (COPD)
RV568 is being developed as a possible treatment of diseases such as smoking related lung disease (also known as Chronic Obstructive Pulmonary Disease - COPD) and asthma.
- Trial name
- NCT01475292
- Testing
- RV568
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Respivert Ltd
Pulmonary Disease, Chronic Obstructive, Hypercapnia
Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients
Humidified Nasal High-flow with Oxygen (HNHF-O2) therapy has been reported to have acute beneficial effects in patients with hypoxemic respiratory failure who have been hospitalized.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxia
- Trial name
- NCT03221387
- Testing
- Humidified nasal high flow with oxygen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Temple University
Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic
A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD
To determine if ABX-IL8 will improve shortness of breath.
- Trial name
- NCT00035828
- Testing
- ABX-IL8
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Abgenix
COPD
Physiotherapy in Patients With Stable Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a lung disease that is characterized by incompletely reversible airflow obstruction. It is projected to be the fifth leading burden of disease worldwide by the year 2020.
- Trial name
- NCT02517411
- Testing
- Standard care, Physiotherapy added to standard care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Pulmonary Disease, Chronic Obstructive
Exacerbations Among Patients Receiving Breztri (EROS Study)
EROS was a retrospective analysis of people with COPD using the MORE2 Registry®. Inclusion required ≥1 severe, ≥2 moderate, or ≥1 moderate exacerbation while on other maintenance treatment.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Retrospective Studies
- Trial name
- NCT06514144
- Testing
- BGF
- Where
- United States
- Volunteers
- 2,409 people
- Sponsor
- AstraZeneca
Asthma, COPD
A Research Study to Explore the Impact of GP Support Via Text Messages to Patients With Asthma and/or COPD
A 6-month randomised controlled trial to evaluate the impact of text message support on symptom control and inhaler adherence for patients with asthma and/or COPD
- Trial name
- NCT06419400
- Testing
- Supportive text messages
- Where
- 7 sites in United Kingdom
- Volunteers
- 6,053 people
- Sponsor
- Accurx
Sleep Apnea, COPD Exacerbation
Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS)
Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) are both frequent respiratory diseases with estimated prevalences between 8 and 15% of the adult population.
- Conditions
- Sleep Apnea, COPD Exacerbation, Overlap Syndrome
- Trial name
- SLEEPOVEA (NCT05958563)
- Testing
- continuous positive airway pressure treatment
- Where
- 15 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Chronic Obstructive Pulmonary Disease
Study to Evaluate Efficacy and Safety of Bronpass Tab. in Patients With Chronic Obstructive Pulmonary Disease
This clinical trial is a multicenter, randomized, double-blind, placebo-controlled, parallel-group dose-response phase 2 clinical trial study to evaluate the efficacy and safety of Bronpass Tab.
- Trial name
- NCT06434792
- Testing
- Bronpass Tab.
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Disease, Pulmonary
Study to Evaluate the Safety and Pharmacokinetics of Inhaled Ciprofloxacin in Patients With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
Objectives of the study are to investigate the safety, tolerability and levels of ciprofloxacin in the lung after single and multiple inhalative administration to patients with mild to moderate COPD (stage I-II according to GOLD…
- Trial name
- NCT01052298
- Testing
- Ciprofloxacin (Cipro inhale, BAYQ3939)
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Bayer
COPD
Tolerance to Electrostimulation in COPD Patients
The study was designed to test the following hypothesis Patients with high cardio-respiratory response to electrostimulation (ES), high perception of pain during ES and high ES-induced muscle fatigue, have low tolerance to ES…
- Trial name
- TOES (NCT00809120)
- Testing
- Neuromuscular Electrical stimulator (Cefar rehab 4 pro)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
COPD, Inactivity, Physical
Actimetry Protocol in COPD Patients
Recently, the principal investigator published an EI predictive Machine Learning algorithm based solely on clinical data, without any physical activity measures, collected from 1 409 patients.
- Trial name
- NCT05918003
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Association pour la Complementarite des Connaissances et des Pratiques de la Pneumologie
Chronic Obstructive Pulmonary Disease Moderate
Beetroot Juice - Effects on Performance in Chronic Obstructive Pulmonary Disease Patients
The purpose is to evaluate exercise performance in patients with Chronic Obstructive Pulmonary Disease (COPD) after supplementing with higher doses of dietary NO3-, compared to previous studies, as beetroot juice for seven days.
- Trial name
- COPD (NCT03020862)
- Testing
- Dietary beetroot juice
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Chronic Obstructive Pulmonary Disease
Randomized Controlled Study to Investigate the Impact of Different Intensities Training on ADL and BODE Index in COPD
The local and systemic manifestations that affect patients with Chronic Obstructive Pulmonary Disease (COPD) cause severe dyspnoea and limitation of functional capacity, leading to impairment in the performance of activities of…
- Trial name
- NCT01977469
- Testing
- Low intensity resistance training, High intensity resistance training, Aerobic training
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Obstructive Pulmonary Disease, Postural; Defect
An Investigation of the Cervical Region Biomechanics in Patients With Chronic Obstructive Pulmonary Disease
The aim of this study is to investigate cervical region biomechanics, muscle performance and respiratory muscle strength in patients with Chronic Obstructive Pulmonary Disease (COPD) compared to healthy subjects.
- Conditions
- Chronic Obstructive Pulmonary Disease, Postural; Defect, Cervical Pain, Cough
- Trial name
- NCT06246370
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Obstructive Pulmonary Disease
Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients
Chronic obstructive pulmonary disease is a respiratory disease that results in progressive airflow limitation and respiratory distress.
- Trial name
- NCT04120142
- Testing
- Pulmonary rehabilitation+IMT, Pulmonary rehabilitation
- Where
- Tunisia
- Volunteers
- 34 people
- Sponsor
- Faculty of Medicine, Sousse
COPD, Interstitial Lung Disease
Effect of Pulmonary Telerehabilitation and Telemonitoring for Patients With Chronic Respiratory Diseases
This research study is being conducted to evaluate the feasibility of using technology to deliver a remote home exercise program and assess the health outcomes of patients with chronic lung diseases.
- Trial name
- NCT05824910
- Testing
- Exercise program (virtual/remote)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Chronic Obstructive Pulmonary Disease (COPD)
Pedometer-based Behavioural Intervention for Individuals With COPD to Stay Active After Rehabilitation
The STAR-study (STay Active after Rehabilitation) investigates in a randomized controlled trial (RCT) the additional effect of a pedometer-based behavior change intervention (BCI) during in-patient pulmonary rehabilitation (PR)…
- Trial name
- STAR (NCT02966561)
- Testing
- Pedometer-based activity promotion, Short patient education and exercise, Pulmonary rehabilitation (Standard care)
- Where
- Germany
- Volunteers
- 418 people
- Sponsor
- University of Erlangen-Nürnberg
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Hypertension
Clinical Registry for the Characterization of the 'Pulmonary Vascular Phenotype' in Patients With Chronic Obstructive Pulmonary Disease
Registry of COPD (Chronic Obstructive Pulmonary Disease) patients who underwent right heart catheterization (RHC) and full clinical evaluation for pulmonary hypertension
- Trial name
- COPD-PH (NCT07102823)
- Where
- 3 sites in Austria, Switzerland and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Graz
Type 2 Diabetes, COPD (Chronic Obstructive Pulmonary Disease)
Lung Cancer Risk in Type 2 Diabetes With COPD: SGLT2 Inhibitors vs. Sulfonylureas
The goal of this observational study is to learn if a specific diabetes medicine can lower the risk of lung cancer in people with type 2 diabetes and chronic obstructive pulmonary disease (COPD).
- Conditions
- Type 2 Diabetes, COPD (Chronic Obstructive Pulmonary Disease), Lung Cancer (Diagnosis)
- Trial name
- NCT07332156
- Testing
- SGLT2 inhibitor, Sulfonylureas (SU), DPP4 inhibitors
- Volunteers
- 21,692 people
- Sponsor
- Samsung Medical Center
Pulmonary Disease, Chronic Obstructive
Randomized Cross Over Study to Assess Efficacy and Safety of BDP/FF and Glycopyrrolate
dose-finding study to assess the optimal dose of glycopyrrolate daily dose on top of BDP/FF in COPD patients.
- Trial name
- NCT01476813
- Testing
- Glycopyrrolate, Comparator
- Where
- United Kingdom
- Volunteers
- 281 people
- Sponsor
- Chiesi Farmaceutici S.p.A.