Clinical trials: COPD Patients
COPD
Maximal Oxygen Uptake (VO2max) in Patients With COPD
Patients with chronic obstructive pulmonary disease (COPD), facing a decline in lung function and compromised quality of life, often benefit from regular exercise (1).
- Trial name
- COPD-MAX (NCT06257381)
- Testing
- VO2max
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
OSA
Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases
The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as Overlap Syndrome (OS). The coexistence of these diseases have cardiovascular morbidity and mortality.
- Trial name
- NCT04903639
- Testing
- sleep study
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Dyspnea
Aerosol Inhalation Treatment for Dyspnea - Patients
The purpose of this protocol is to develop and test aerosol furosemide, as a treatment that has the potential to significantly improve symptom management and enhance the quality of care for patients with intractable dyspnea.
- Trial name
- NCT02524054
- Testing
- Furosemide, Aerosolized saline
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Pulmonary Tuberculosis Suspected, Other Specified Chronic Obstructive Pulmonary Disease
ENOSE in Pulmonary Tuberculosis in Yogyakarta
Electronic noses detecting patterns of volatile molecules have recently been introduced for different diagnostic purposes. The diagnostic accuracy of a prototype e-nose device (Bruins et al (2013) in Bangladesh showed sensitivity…
- Conditions
- Pulmonary Tuberculosis Suspected, Other Specified Chronic Obstructive Pulmonary Disease, Pulmonary Tuberculosis TB (+) Histology, (-) Bacteriology
- Trial name
- YOGYATBNOSE (NCT02219945)
- Testing
- 5 min exhaled breath sampling with soft nose clamp
- Where
- Indonesia
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Tjip van der Werf
Copd
Efficacy of Osteopathic Manipulative Techniques in Patients With Chronic Obstructive Pulmonary Disease
This study will test the efficiency of rib rising technique and thoracic lymphatic pump technique combining with manual diaphragmatic release technique in patients with chronic obstructive pulmonary disease
- Trial name
- NCT06865703
- Testing
- diaphragmatic release technique, rib raising technique in group A, THORACIC LYMPHATIC PUMP TECHNIGUE
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Beni-Suef University
COPD, COPD (Chronic Obstructive Pulmonary Disease)
Pulmonary Rehabilitation Frequency in COPD Patients
Chronic obstructive pulmonary disease (COPD) is a common condition that can cause breathlessness and reduced physical capacity. Pulmonary rehabilitation (PR) is an effective treatment, but traditional programs often require…
- Trial name
- NCT07575841
- Testing
- Pulmonary Rehabilitation
- Volunteers
- 158 people
- Sponsor
- Hospital Universitario Fundación Alcorcón
Chronic Obstructive Pulmonary Disease, Noninvasive Ventilation
Determination of the Prevalence and Severity of Expiratory Flow Limitation in Chronic Obstructive Pulmonary Disease Patients
Expiratory Flow Limitation (EFL) occurs when the airways become compressed, which usually results when the pressure outside the airway exceeds the pressure inside the airway.
- Trial name
- NCT03851510
- Testing
- Vector ventilator, Resmon Pro
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Philips Respironics
Chronic Obstructive Pulmonary Disease
Evaluation of Efficacy and Safety of Formoterol in Patients With COPD Compared With Placebo in Patients in Japan, EU
The purpose of this study is to show the efficacy and safety of formoterol for the maintenance treatment of patients with COPD compared with placebo in patients in Japan and in European countries during 12 weeks.
- Trial name
- OCEAN (NCT00628862)
- Testing
- Formoterol Turbuhaler® 4.5mg, Formoterol Turbuhaler® 9 mg
- Where
- 47 sites in Bulgaria, Japan and 3 more
- Volunteers
- 613 people
- Sponsor
- AstraZeneca
COPD, Upper Extremity
Cognitive Impairment and Upper Extremity Performance in COPD
Within the scope of this study, COPD patients will be divided into two groups according to cognitive dysfunction. Pulmonary function test, COPD assessment scale, Mini-Mental State Examination and Montreal Cognitive Assessment…
- Conditions
- COPD, Upper Extremity, Upper Limb Function, Cognitive Impairment
- Trial name
- COPD (NCT05137483)
- Testing
- Functional tests
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Heart Failure, Copd
Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD
Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age.
- Conditions
- Heart Failure, Copd, Nutritional Supplementation, Pulmonary Rehabilitation
- Trial name
- NCT04432194
- Testing
- Nutritional supplementation and Pulmonary Rehabilitation
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
COPD
Immuno-inflammatory Response of Erdosteine in COPD
Chronic obstructive pulmonary disease (COPD) remains a major contributor to global morbidity and mortality, exposing healthcare systems to a significant economical and social load.
- Trial name
- NCT07329946
- Testing
- Erdosteine, Standard of Care (SOC)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Pierachille Santus, MD, PhD
COPD, Severe Systemic Illness-induced Respiratory Muscle Wasting
Effects of Inspiratory Muscle Training on Dyspnea Perception During Exercise in Patients With COPD
Patients with chronic obstructive pulmonary disease are often limited in their exercise capacity by intolerable shortness of breath (dyspnea).
- Trial name
- IMTCOCOPD (NCT01900873)
- Testing
- Inspiratory Muscle Strength Training, Inspiratory Muscle Endurance Training
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- KU Leuven
COPD
Respiratory Regulation With Biofeedback in COPD
Dyspnea is the main reason that patient with chronic obstructive pulmonary disease(COPD) to sedentary. It's a vicious circle of deteriorating lung function.
- Trial name
- RRBCOPD (NCT03640260)
- Testing
- breathing regulation with physical activity
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- Changhua Christian Hospital
COPD Patients, Mechanical Ventilation
Prognostic Value Cardiac Dysfunction Assessed by Bedside Echocardiography in Critically Ill COPD Patients Requiring Mechanical Ventilation
Chronic obstructive lung disease (COPD) is a major cause of morbidity and mortality, and is a major reason for ICU admission. Cardiac function is often impaired in this disease but its association with clinical outcome has not…
- Trial name
- NCT02099279
- Testing
- echocardiography examination
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Jinhua Central Hospital
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Early Warning System
The study will begin in 2013 whereby patients having an early warning system (EWS) alert will be randomized to be seen by the rapid response team (RRT) for triage versus usual care.
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cancer, Diabetes Mellitus
- Trial name
- NCT01741480
- Testing
- Early warning system monitoring., routine care
- Where
- United States
- Volunteers
- 571 people
- Sponsor
- Washington University School of Medicine
COPD
Non-interventional Study Related to Fixed LAMA/LABA/ICS Triple Therapy
This is a prospective non-interventional trial to measure the health related quality of life of patients with chronic obstructive pulmonary disease (COPD) on a fixed LAMA/LABA/ICS triple therapy (Trimbow®) and characterisation of…
- Trial name
- TriOptimize (NCT04355546)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 94 people
- Sponsor
- Chiesi UK
Emphysema, COPD
Sequential Endoscopic Lung Volume Reduction
Patients with heterogenous emphysema benefits from endoscopic lung volume reduction. Until now the technique is limited to one lobe. In case of collateral ventilation patients show no improvement.
- Trial name
- NCT00613860
- Testing
- Zephyr endobronchial valve
- Where
- 3 sites in Germany
- Sponsor
- Heidelberg University
Chronic Obstructive Pulmonary Disease, Invasive Mechanical Ventilation
Trial to Study Intubation Rates of Non-invasive Ventilation Using Pressure Support Ventilation (PSV) Versus Adaptive Support Ventilation (ASV) Mode in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The clinical course of chronic obstructive pulmonary disease (COPD) is associated with recurrent episodes of exacerbation that results in respiratory failure.
- Conditions
- Chronic Obstructive Pulmonary Disease, Invasive Mechanical Ventilation, Adaptive Support Ventilation
- Trial name
- PSV vs ASV for (NCT02877524)
- Testing
- Adaptive support ventilation, Pressure support ventilation
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Respiratory Failure, Respiratory Insufficiency
Comparison of High-flow Oxygen vs. BiPAP in Type II (Hypercapnic) Respiratory Failure
A retrospective cohort study of all patients treated for type II (hypercapnic) respiratory failure with either High-Flow Oxygen Therapy or Non-Invasive Ventilation in a general adult hospital.
- Conditions
- Respiratory Failure, Respiratory Insufficiency, Respiratory Tract Diseases, COPD
- Trial name
- NCT03443479
- Testing
- Non-Invasive Ventilation, High-Flow Nasal Cannula
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- Hôpital de Verdun
Chronic Obstructive Pulmonary Diseases
The Role of Ambulatory Oxygen in Improving the Effectiveness of Pulmonary Rehabilitation for COPD Patients
Pulmonary rehabilitation (PR) is an exercise program tailored for patients with chronic lung disease that is a core part of the management of patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02707770
- Testing
- Pulmonary Rehabilitation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College Healthcare NHS Trust