Clinical trials: COPD Patients, open to volunteers
Chronic Obstructive Pulmonary Disease, Takotsubo Cardiomyopathy
Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital
The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these…
- Conditions
- Chronic Obstructive Pulmonary Disease, Takotsubo Cardiomyopathy, Acute Heart Failure
- Trial name
- CATCH (NCT06597331)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Sahlgrenska University Hospital
Pulmonary Disease (COPD), Chronic Obstructive
Comparison of Arterial and Capillary Blood Gas Analyses in Patients With Respiratory Distress Due to COPD or APE
The assessment of gas exchange is crucial for the management of patients suffering from respiratory distress due to an exacerbation of chronic obstructive pulmonary disease (COPD) or cardiogenic acute pulmonary edema (APE).
- Trial name
- GAZOCAP (NCT07835945)
- Testing
- Capillary blood gas analysis
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Obstructive Pulmonary Disease (COPD)
Smartphone-based Self-Management Support Program to Enhance Quality of Life in Patients With COPD
The goal of this study is to find out if a smartphone-based program (called 3S-C) can help people with COPD live better, healthier lives. It will also look at how the program affects their knowledge, habits, and overall health.
- Trial name
- NCT06888557
- Testing
- Smartphone-based self-management support program ( 3S-C)
- Where
- 3 sites in Hong Kong
- Volunteers
- 130 people
- Sponsor
- Hong Kong Metropolitan University
COPD Exacerbation (AECOPD), Pulmonary Hypertension
Dynamic Changes in Right Ventricle and Pulmonary Artery Coupling Among COPD Patients With Acute Exacerbation
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and manageable disease characterized by persistent respiratory symptoms and airflow limitation.
- Trial name
- NCT07694713
- Testing
- Echocardiography assessment
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease (COPD), Traditional Chinese Medicine Syndrome
Multi-Omics Study of COPD Stages and Traditional Chinese Medicine Syndromes
This is a multicenter, prospective, observational cohort study of patients with chronic obstructive pulmonary disease (COPD), individuals with pre-COPD, and healthy participants.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Traditional Chinese Medicine Syndrome, Multi-omics
- Trial name
- NCT07873489
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Chronic Obstructive Pulmonary Disease
A Study to Evaluate the Efficacy and Safety of RSS0343 Tablets in Patients With Chronic Obstructive Pulmonary Disease
This study is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial designed to evaluate the efficacy and safety of RSS0343 tablets in patients with COPD.
- Trial name
- NCT07349524
- Testing
- RSS0343 tablets
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Reistone Biopharma Company Limited
COPD Exacerbation, Care Transitions
Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients
Transitions of Care (TOC) between hospital, ambulatory, and home settings for high-risk, frequently hospitalized adults with chronic diseases, such as chronic obstructive pulmonary disease (COPD) are complex, costly, and…
- Trial name
- TELE-TOC (NCT05897125)
- Testing
- Virtual at Home Medication Reconciliation Visit(s), Virtual At Home Medication Education Visit(s), COPD advanced practice nurse Inpatient Consult
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- University of Chicago
Chronic Obstructive Pulmonary Disease
A Study About Association Between Microbiome, Metabolome and Clinical Characteristics in COPD Patients
The goal of this observational registry study is to compare characteristics of gut and sputum microbiome and metabolome among COPD patients with significant smoking history, COPD patients without significant smoking history and…
- Trial name
- NCT06101459
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Chronic Obstructive Pulmonary Disease
Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo
Chronic Obstructive Pulmonary Disease is a leading cause of global morbidity and mortality, especially in low- and middle-income countries. Exacerbations accelerate disease progression and increase the risk of death.
- Trial name
- iCHOROS (NCT07069829)
- Where
- 36 sites in Argentina, Colombia and 10 more
- Volunteers
- 1,400 people
- Sponsor
- AstraZeneca
COPD, ILD
SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection
This is a prospective observational study that evaluates whether the Shuttle Walking Test (SWT) can predict postoperative symptoms, particularly dyspnea, in patients with chronic respiratory diseases undergoing lung resection.
- Conditions
- COPD, ILD, Bronchiectasis, Lung Cancer NOS
- Trial name
- SWEEP (NCT07102589)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
COPD Exacerbation, ICU
Characteristics and Outcomes of Patients Admitted to ICU for a Severe Acute Exacerbation of COPD.
The objective of this prospective observational study is to describe the epidemiological, clinical and biological characteristics of patients admitted in ICU for a severe acute exacerbation of COPD, and to assess the different…
- Trial name
- COPDregister (NCT06257329)
- Testing
- register
- Where
- 4 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Alexis FERRE
Cardio-vascular Disease, Depression Disorders
Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland
In Phase B, the aim is to evaluate the myCare Start service in routine care within the ambulatory primary care medicine and community pharmacy setting in Switzerland.
- Conditions
- Cardio-vascular Disease, Depression Disorders, Diabetes, COPD
- Trial name
- myCare Start-I (NCT07036471)
- Testing
- myCare Start
- Where
- Switzerland
- Volunteers
- 1,600 people
- Sponsor
- University of Geneva, Switzerland
COPD
KOrea COpd Subgroup Registry and Subtype Research
The KOrea COpd Subgroup Study team (KOCOSS) cohort is an ongoing, longitudinal, prospective, non-interventional and observational study within the Korean COPD patients.
- Trial name
- KOCOSS (NCT02800499)
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Konkuk University Medical Center
Chronic Obstructive Pulmonary Disease (COPD)
Fractional Exhaled Nitric Oxide and Exacerbations of COPD
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with recurrent exacerbations despite guideline-based therapy.
- Trial name
- NCT07396311
- Testing
- No intervention assigned
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
COPD
Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital
The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with hypoxemia/respiratory distress.
- Trial name
- NCT07222410
- Testing
- Closed loop oxygen control, Manual titration
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Fisher and Paykel Healthcare
Chronic Obstructive Lung Disease, Respiratory Ilness
InvEstigating oeStrogen Signalling and the Effect upoN the exTracelluar Matrix In pAtients With Obstructive Lung Disease
This study aims to understand the role of oestrogen in patients with asthma and Chronic Obstructive Pulmonary Disorder (COPD). Therefore, what is the effect of oestrogen in these participants compared to controls (those without…
- Conditions
- Chronic Obstructive Lung Disease, Respiratory Ilness, Estrogen Deficiency, Asthma
- Trial name
- ESSENTIAL (NCT06713512)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
COPD (Chronic Obstructive Pulmonary Disease)
A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of HSK39004 Inhalation Suspension in Patients With COPD
The purpose of this study is to evaluate the efficacy and safety of HSK39004 Inhalation Suspension in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT07658339
- Testing
- HSK39004 Inhalation Suspension
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
COPD (Chronic Obstructive Pulmonary Disease)
Effect of Silymarin as Add on Therapy on Oxidative Stress, Pulmonary Function and Quality of Life in Stable COPD Patients.
The goal of this clinical trial is to learn if Silymarin works to reduce oxidative stress, improve pulmoary function and quality of life in stable COPD patients. It will also learn about the safety of drug Silymarin.
- Trial name
- NCT07123922
- Testing
- Silymarin
- Where
- Bangladesh
- Volunteers
- 70 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
COPD, COPD III/IV
"The Effect of Inhaled Nitroglycerin for COPD Patients
this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD
- Trial name
- iNGCOPD (NCT06785337)
- Testing
- Inhaled nitroglycerin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Chronic Respiratory Diseases, Cystic Fibrosis
Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases
Assessment of cardiovascular disorders using echocardiography and arterial stiffness; comparative noninvasive assessment of volatile organic compound (eVOC) exhale breath patterns in patients with different chronic respiratory…
- Conditions
- Chronic Respiratory Diseases, Cystic Fibrosis, Lymphangioleiomyomatosis, Hypersensitivity Pneumonitis
- Trial name
- NCT05727852
- Testing
- Breath test using the Compact PTR-TOF-MS, Portable cardiac monitor "CardioQvark", Assessment of arterial stiffness using the VaSera VS-1500N
- Where
- Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University