Clinical trials: CORE
Hereditary Ataxia, Spinocerebellar Degenerations
Telerehabilitation, Core Stability Exercises and Hereditary Ataxia (TRCore-ataxia)
Hereditary ataxias (HA) are a heterogeneous group of degenerative diseases of the cerebellum, brain stem and spinal cord. People who suffer from AH, among other symptoms, present deficiencies in the stability of the trunk, which…
- Conditions
- Hereditary Ataxia, Spinocerebellar Degenerations, Cerebellar Ataxia
- Trial name
- TRCore-ataxia (NCT06152133)
- Testing
- Therapeutic core stability exercises
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Universitat de Lleida
Patellofemoral Pain Syndrome
Effects of Core Stability Exercises in Patients With Patellofemoral Pain Syndrome
The purpose of the study is to compare the effects of routine physical therapy with and without core stability exercises on pain and range of motion, in patients with patellofemoral pain syndrome.
- Trial name
- NCT05261100
- Testing
- Core stability exercises, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Lahore
Stroke, Acute Ischemic
Endovascular Treatment for eXtra-Large Ischemic Stroke
The role of endovascular thrombectomy in patients with extra-large ischemic burden is still unclear. The XL STROKE-2 randomized trial is aiming to investigate the efficacy and safety of mechanical thrombectomy in acute…
- Trial name
- XL STROKE-2 (NCT06388148)
- Testing
- Medical management, Endovascular thrombectomy
- Where
- 2 sites in China
- Volunteers
- 286 people
- Sponsor
- Zhongming Qiu
Healthy Volunteers
Bioequivalence Study of Prednisolone and Dexamethasone
The purpose of this study is to compare two different glucocorticoids, prednisolone and dexamethasone at two different doses for their organ specific effects, utilizing modern day standards.
- Trial name
- CORE (NCT04733144)
- Testing
- Prednisolone, Dexamethasone
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Osteonecrosis of the Femoral Head
Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH)
This retrospective observational study evaluates the clinical and radiological outcomes of patients with early-stage osteonecrosis of the femoral head treated with a combination of core decompression, stromal vascular fraction…
- Trial name
- TM-ONFH (NCT07560163)
- Testing
- Core decompression, stromal vascular fraction (SVF), Hyperbaric Oxygen Therapy (HBOT)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Stroke
Effects of Core Strengthening and PNF Pattern on Static Balance and Plantar Pressure in Chronic Stroke Patients
Stroke is a neurological disease characterized by neurological deficits caused by insufficiency of blood supply to brain. Disruption of blood supply to brain can be due to blockage of blood supply (ischemic) or leakage of blood…
- Trial name
- NCT06346652
- Testing
- Routine Physical Therapy, Routine Physical Therapy+ PNF and Core Stregthening
- Where
- Pakistan
- Volunteers
- 73 people
- Sponsor
- University of Lahore
Hypothermia
Pre-warmed Intravenous Fluids and Monitored Anesthesia Care
The aim of the study is to compare effect of pre-warmed intravenous fluids on the early outcomes in ambulatory patients undergoing monitored anesthesia care.
- Trial name
- NCT01722955
- Testing
- Pre-warmed fluids, Room temperature fluids
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Sport, Amputation
Isometric Core Training and Swimming Performance in Adolescent Amputee Swimmers
Adolescent amputee swimmers often experience challenges related to trunk stabilization, postural control, and efficient force transfer during swimming because of asymmetric biomechanics associated with limb loss.
- Conditions
- Sport, Amputation, Paralympic Athletes
- Trial name
- NCT07619963
- Testing
- Isometric Core Training, Standard Swimming Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Gelisim University
Temperature, General Anesthesia
Correlation Between Core Temperature and Skin Temperature Measured by 3M SpotOn
Core temperature should be monitored under general anesthesia. Recently developed 3M Spoton skin temeprature which is applied on temporal artery is correlated with core temperature measure by esophageal prove in several studies.
- Trial name
- Temperature (NCT03745079)
- Testing
- Esophagus temperature monitoring, Spoton Temporal, Spoton Carotid
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Ajou University School of Medicine
Cervical Radiculopathy
Effect of Core Stabilization Exercises on Patients With Cervical Radiculopathy
The goal of this clinical trial is to evaluate the effect of core stabilization exercise on functional outcome and craniovertebral angle which is the angle of forward head , in adults with cervical radiculopathy.
- Trial name
- NCT07365917
- Testing
- Core stabilization exercises, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Rugby
Core Work and Sports Bandage in Rugby Players
Introduction. Lower limb injuries are characteristic of rugby players. Core exercises aim to improve ankle stability. The ankle bandage in 8 is used in the approach to injuries to provide better stability in the joint.
- Trial name
- NCT03865797
- Testing
- Experimental, Control active
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Sport Injuries
PNF Effects on Volleyball Performance
Volleyball is a team sport that demands high levels of skill and strategy; it has gained significant popularity in Türkiye, particularly among adolescents.
- Trial name
- NCT07913217
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Exercise, Muscle Weakness
The Effect of Core Stability Exercises on Pain, Muscle Strength, and Muscle Architecture in Tennis Players With Rotator Cuff Lesions
This study aims to shed light on the supraspinatus and infraspinatus muscles, which play a significant role in rotator sheath tendinopathy and tears.
- Conditions
- Exercise, Muscle Weakness, Rotator Cuff Injuries
- Trial name
- NCT06402162
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara University
Hereditary Ataxia, Spinocerebellar Degenerations
Core Stability Exercises and Hereditary Ataxia
The hereditary ataxias are a group of genetic disorders characterized by slowly progressive incoordination of gait and balance impairments in sitting and standing.
- Conditions
- Hereditary Ataxia, Spinocerebellar Degenerations, Cerebellar Ataxia
- Trial name
- Core-ataxia (NCT04750850)
- Testing
- Therapeutic core stability exercises, Usual care
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universitat Internacional de Catalunya
Athletes, Adolescent
Core Stability for Baseball Batting in Adolescents
Baseball batting is important to winning the games. Baseball batting is achieved by proximal-to-distal sequencing of body movements and controlled by the neuromuscular system.
- Trial name
- NCT04713696
- Testing
- Functional training, Routine training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Acute Ischemic Stroke
PROMISE: PRedictors Of Good outcoMes in Thrombectomy for Large Infarct Core Stroke Evaluation
Identify the factors associated with a favorable clinical outcome in participants with acute ischemic stroke and large core infarcts within 24 hours of onset who are treated with endovascular intervention.
- Trial name
- NCT06016348
- Testing
- Endovascular treatment
- Where
- 4 sites in Vietnam
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 115 People's Hospital
Multiple Sclerosis, Gait Disorders, Neurologic
Effects of Core Stability Training on Gait in Multiple Sclerosis Patients
Gait and mobility are among the functions frequently affected in Multiple Sclerosis (MS) and have a negative impact on quality of life.
- Trial name
- NCT03442049
- Testing
- Physiotherapy - Study group, Physiotherapy - control group
- Volunteers
- 68 people
- Sponsor
- Hacettepe University
Angina Pectoris, Angina, Unstable
Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study
This pilot study is going to examine the hypothesis that in coronary arteries, soft lesions that contain lipid cores, but are not calcified or fibrotic and are located in proximity to side branches, are associated with side…
- Conditions
- Angina Pectoris, Angina, Unstable, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT00905671
- Testing
- LipiScan Coronary Imaging Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Infraredx
Locally-Advanced Non-Small Cell Lung Cancer, Radiotherapy
Centrally Confined 8Gy/1f to Tumor Core Followed by Concurrent Chemoradiotherapy for Unresectable Stage III NSCLC
This is a single-center, prospective, open-label, single-arm phase I exploratory study designed to evaluate the safety and feasibility of a novel central immune-priming radiotherapy strategy in patients with unresectable stage…
- Trial name
- NCT07523464
- Testing
- Centrally Confined 8 Gy/1 Fraction Immune-Priming Radiotherapy to the Tumor Core Followed by Definitive Concurrent Chemoradiotherapy
- Volunteers
- 24 people
- Sponsor
- Anhui Provincial Hospital
Patients Scheduled for Brain Surgery
Effect of Heated Breathing Circuit on Intraoperative Core Temperature and Systemic Inflammation After Brain Surgery: a Prospective Randomized Study
Mechanical respiration during general anesthesia causes cold and dry gases to reach the lower airway, reduce the function of the airway mucosa, and cause accumulation of secretions.
- Trial name
- NCT03491332
- Testing
- conventional circuit, conventional humidification circuit, new humidifaction heat circuit
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Yonsei University
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