Clinical trials: CORE
Hyperthermic Intraperitoneal
Use of Water Warming/Cooling Garment to Maintain a Constant Intraoperative Core Target Temperature in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Proof-of-Concept Study
To look at the feasibility of using a water warming/cooling garment (called the ALLON system) to maintain a target body temperature during surgery and chemotherapy perfusion (a method of pouring chemotherapy throughout your…
- Trial name
- NCT05474352
- Testing
- Allon System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Body Temperature Changes, Heat Stress
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part III
Occupational heat stress directly threatens workers' ability to live healthy and productive lives. Heat exposed workers are at an elevated risk of experiencing impaired work performance and cognitive function leading to a greater…
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT06630832
- Testing
- Simulated work in the heat with no cooling during rest breaks, Simulated work in the heat with partial cooling during rest breaks, Simulated work in the heat with full cooling during rest breaks
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Multiple Sclerosis
The Effects of Synchronous and Asynchronous Pilates Training Based on Telerehabilitation on Core Stabilization, Balance, Cognitive Functions, and Quality of Life in Individuals With Multiple Sclerosis: A Single-Blind Randomized Controlled Trial
This study will compare live video-based and prerecorded video-based Pilates programs in 38 adults aged 18-65 years with multiple sclerosis. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07893925
- Testing
- Synchronous Telerehabilitation-Based Pilates, Asynchronous Telerehabilitation-Based Pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Yuzuncu Yil University
Vascular Access Complication, Hemodialysis Access Failure (Disorder)
Vascular Access Outcome Measure for Function: a vaLidation Study In haemoDialysis
A functioning vascular access provides a lifeline for patients requiring haemodialysis but vascular access dysfunction remains one of the leading causes of excessive morbidity, mortality and healthcare costs in this group.
- Trial name
- VALID (NCT03969225)
- Where
- 10 sites in Australia, Canada and 5 more
- Volunteers
- 702 people
- Sponsor
- The University of Queensland
Pancreatic Neoplasm
Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
- Trial name
- COS (NCT02181140)
- Testing
- EUS guided FNA and fine needle punction
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Brain Injury, Vascular, Sequelae
The Effectiveness of Core Stability Exercises
This study assess the effectiveness of core stability exercises performed in subacute phase of stroke. Half of participants will receive conventional physiotherapy, while the other half will receive core stability exercises and…
- Conditions
- Brain Injury, Vascular, Sequelae, Stroke Syndrome, Movement; Disorder, Treatment-Induced
- Trial name
- CORE (NCT03975985)
- Testing
- Core stability exercises (CSE), Conventional Physiotherapy
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Hepatitis B
NASVAC Phase-III Trial in Chronic Hepatitis B (CHB) Patients
The general objective of the present clinical trial is to compare the therapeutic efficacy of a combination therapeutic vaccine containing hepatitis B surface antigen (HBsAg) and hepatitis B core antigen (HBcAg) [later called…
- Trial name
- NASVAC (NCT01374308)
- Testing
- NASVAC, Pegylated interferon alpha 2b
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Clinical Research Organization, Dhaka, Bangladesh
Post-Op Complication, Post Colo- Rectal Surgeries
Core Stability Exercises Versus Tai Chi Exercises on Dynamic Balance After Colo-rectal Surgeries.
Forty patients from both genders, who have undergone colorectal surgeries. Their ages ranged from 25 to 40 years. The participants was selected from El Mataria teaching hospital and randomly distributed into two equal groups.
- Conditions
- Post-Op Complication, Post Colo- Rectal Surgeries, Colo -Rectal Surgeries
- Trial name
- NCT07451444
- Testing
- Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Trigeminal Neuralgia
Defining Core Outcome Sets in Trigeminal Neuralgia
The aim of this study is to determine what patients with trigeminal neuralgia (TN), clinicians and researchers in the field, consider to be the most important outcomes to be expected after undergoing treatment for trigeminal…
- Trial name
- TRINCOS (NCT04272385)
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Image-guided Biopsy, Complications
Renal Parenchymal Core Needle Biopsy
Percutaneous image-guided parenchymal renal biopsy has been used to detect the different pathologies of renal parenchyma, to define the degree of reversible changes, and to define when the medical treatment fails.
- Conditions
- Image-guided Biopsy, Complications, Kidney Glomerulus
- Trial name
- NCT02758535
- Testing
- coaxial renal biopsy, noncoaxial renal biopsy
- Where
- Iran
- Volunteers
- 166 people
- Sponsor
- Modarres Hospital
Healthy Subjects
Comparative Effects of Vocal and Breathing Exercises on Respiratory Function and Trunk Stability in Women
The goal of this randomized clinical trial is to investigate whether vocal exercises or breathing exercises improve respiratory function and trunk stability in healthy adult women aged 18-65.
- Trial name
- VO vs BE (NCT07175844)
- Testing
- Vocal exercises, Breathing exercises
- Where
- 2 sites in Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Body Temperature Regulation
Measuring Core Body Temperature Using a Novel Non-invasive Sensor
The Double Sensor examined in this trial was developed by Dräger Company and is a novel non- invasive device for assessing core body temperature.
- Trial name
- Dräger (NCT02691832)
- Testing
- "Dräger" double sensor
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Diastasis Recti Abdominis
Effects of SEMG Biofeedback With Core Muscle Strengthening Exercises and Kinesiotaping on Diastasis Recti in Post-partum Women
Diastasis Rectus Abdominis is quite common during and after pregnancy. Abdominal core strengthening exercises have been proven to be very effective in reducing Inter rectus distance, however, the role of Biofeedback EMG assisted…
- Trial name
- NCT05897255
- Testing
- Surface EMG Biofeedback
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Flexor Tendon Repair
Repair of Flexor Tendon Injuries With Eight Strand Core Stitch Without Postoperative Splinting
Evaluation of early active postoperative mobilisation in flexor tendon injuries without postoperative splinting
- Trial name
- NCT03938935
- Testing
- Absorbable polydioxanone suture (PDS)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Mina Micheal Anwer Fahmy
Lower Urinary Tract Symptoms, Skeletal Muscle
Examining the Relationship Between Core Muscles and Bladder Issues in Children
The goal of this observational study is to learn about functional bladder problems in children. The main questions it aims to answer are: Does bladder symptoms in children have an effect on core muscles? How do core muscles…
- Trial name
- NCT06317116
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Prolonged Mechanical Ventilation, Protein Deficiency
High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation
The goal of this clinical trial is to learn about in patients with prolong mechanical ventilation. This main questions aims to answer are: High protein formula intake benefit in successful weaning from ventilator Core muscle…
- Trial name
- NCT05932134
- Testing
- UC + high protein diet (HP), UC + HP + core muscle rehabilitation, UC + HP + core muscle rehabilitation + neuromuscular electric stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Coronary Artery Disease
Comparison of Temperature Using Tracheal Thermometer and Pulmonary Artery Catheter in Adult Patients Undergoing CABG
In anesthesia, monitoring of core body temperature is one of important factors. Measurement of temperature using a pulmonary artery catheter is representative one of core temperature measurements.
- Trial name
- TVP (NCT05595616)
- Testing
- Insertion of tracheal thermometer and pulmonary artery catheter
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Pusan National University Yangsan Hospital
Root Canal Infection, Tooth Defect
Clinical Trial of Modified Endocrown and Personalized Post-core and Crown for Large-area Tooth Defects After Root Canal Treatment
This study intends to adopt a multicenter, randomized controlled, single-blind, non-inferiority clinical trial design. 246 premolars that meet the inclusion criteria after complete root canal treatment will be selected from the…
- Conditions
- Root Canal Infection, Tooth Defect, Post and Core Technique
- Trial name
- NCT07206108
- Testing
- modified endocrown
- Where
- China
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Idiopathic Scoliosis
The Effect of Core Stability Exercises on Idiopathic Scoliosis in Adolescent Females
To evaluate the efficacy of core stability (CS) exercises on curve magnitude, posture, trunk deformity and quality of life in adolescent females with idiopathic scoliosis.
- Trial name
- NCT06803121
- Testing
- Traditional treatment, Core stability exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
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