Clinical trials: CORE
Aging, Constipation
Probiotics in Elderly Patients With Medical Conditions
Study of efficacy of probiotic in older patients with multiple co-morbidites and constipation
- Conditions
- Aging, Constipation, Multi-Core Disease
- Trial name
- Probiotics (NCT04035616)
- Testing
- microbial cell preparation [MCP]
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Acute Ischemic Stroke
Methylprednisolone With Endovascular Thrombectomy for Large Ischemic Stroke
It is uncertain whether intravenous methylprednisolone improves outcomes for acute anterior circulation large vascular occlusion (LVO) patients with a large infarct core.
- Trial name
- MATCH (NCT06870448)
- Testing
- Methyprednisolone sodium succinate
- Where
- China
- Volunteers
- 1,614 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Stroke
Comparison of Core Stability and Otago Exercise on Balance and Quality of Life in Patients With Stroke
Core stability and otago exercise program has been proved to be effective in many conditions like muscles strenghing, gait improvement and relieving of pain.
- Trial name
- NCT05591378
- Testing
- core stability exercises, otago exercises
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Hepatitis B Virus
Mutations of the Pre-core Region of Hepatite B Virus (HBV)
Hepatitis B virus (HBV) infection constitutes a major public health threat worldwide. A total of 92 patients with HBeAg-negative chronic hepatitis B infection were recruited at Amiens University Hospital.
- Trial name
- HEPATITEB (NCT03625258)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Non-specific Low Back Pain
Core Muscle Response to Backward Walking in Patients With Non Specific Low Back Pain
evaluation of core muscles endurance and strength following backward walking training programe
- Trial name
- NCT05687695
- Testing
- backward walking program, core training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Postural Control, Athletic Performance
Core Strength Training, Anthropometry, and Postural Control in Youth Optimist Sailors
Optimist dinghy sailing is a highly demanding youth watersport characterized by prolonged, high-intensity isometric hiking postures and rapid dynamic weight shifts required to preserve boat trim, balance, and sail power output.
- Conditions
- Postural Control, Athletic Performance, Physical Fitness, Core Stability
- Trial name
- NCT07802782
- Testing
- Core Strength Training (CST), Technical Sailing Training (TST)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Stroke
Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors
This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors.
- Trial name
- NCT07887360
- Testing
- Lower Limb PNF Combined with Core Stability Training, Lower Limb PNF alone
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ibadat International University, Islamabad
Breast Pumping
Evaluation of Fluid-Filled Expression Core Technology Study - I
A functional model of a fluid-filled, smaller dead volume breast pump has been developed in order to more closely mimic the breastfeeding infant.
- Trial name
- Effect-1 (NCT03921918)
- Testing
- Breast Pump
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medela AG
Chronic Low Back Pain
Are Supervised Exercises and TENS Necessary Along With Prescribed Home Exercises for Chronic Low Back Pain?
The purpose of this study is to compare the added effects of TENS and Supervised Motor Control Exercises (SMCE) over Unsupervised Home Exercise Program (UHEP) on disability, pain and other outcomes.
- Trial name
- NCT02343315
- Testing
- TENS, SMCE, UHEP
- Sponsor
- Kathmandu University School of Medical Sciences
Stroke
Combining Transcranial Direct Current Stimulation and Core Stability Exercise on Trunk in Stroke Patient
To evaluate the effects of the combining transcranial direct current stimulation with core stability exercises on trunk performance in poststroke hemiparetic patients, the secondary outcome is to evaluate the balance and the…
- Trial name
- TCDC (NCT06882213)
- Testing
- transcranial direct current stimulation, core stability exercise.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Amphetamine Use Disorders
Closed-loop cTBS for the Core Clinical Features of Methamphetamine Use Disorder
Using specific EEG biomarkers in methamphetamine-dependent individuals, this study systematically probes closed-loop continuous Theta-burst Stimulation (cTBS) based on brain states, assessing dosage, neurologic and behavioral…
- Trial name
- NCT06457243
- Testing
- Closed-loop cTBS stimulation based on addiction induced states
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Flat Epithelia Atypia, Intraductal Papilloma Without Atypia
The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle Biopsy
This research study is studying a surgical intervention to rule out the presence of cancer in participants that have been diagnosed with flat epithelial atypia (FEA) or intraductal papilloma without atypia (IPWA) by core needle…
- Trial name
- NCT02489617
- Testing
- Pathologic evaluation of excised tissue
- Where
- 18 sites in United States
- Volunteers
- 246 people
- Sponsor
- Dana-Farber Cancer Institute
Flexible Flatfoot
Foot-Core Training With/Without Visual Feedback in Pediatric FPP
This study investigates flexible pes planus (flat feet) in children, a condition where the medial arch collapses during weight-bearing, affecting gait, balance, and foot function.
- Trial name
- NCT07578974
- Testing
- Foot Core Training, Foot Core Training with Visual Feedback
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Patients With Chronic Mechanical LBP
Core Stability Exercise Versus Aerobic Exercise on Pain, Range of Motion and Function in Patients With Chronic Mechanical Low Back Pain: Randomized Controlled Trial
Chronic mechanical low back pain (CMLBP) is a prevalent musculoskeletal condition characterized by persistent pain originating from the spine, muscles, ligaments, or intervertebral discs.
- Trial name
- NCT06634511
- Testing
- core stability exercises
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Cairo University
Neuromuscular Disease, Malignant Hyperthermia
The Prevalence of RYR1-related Disease
The skeletal muscle ryanodine receptor (RYR1) gene encodes an important calcium channel in skeletal muscle, with an important role in muscle contraction. Mutations (i.e.
- Conditions
- Neuromuscular Disease, Malignant Hyperthermia, Congenital Myopathy, Multiminicore Disease
- Trial name
- NCT06791369
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- King's College London
Atrial Fibrillation, Arrhythmias, Cardiac
Validation Study of WITHINGS BPM Core for the Detection of Atrial Fibrillation
The proposed clinical study aims to validate the diagnostic performance, compared to a reference ECG, of the electrocardiographic function of the BPM Core developed by Withings for the automatic identification of atrial…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- Core AF (NCT04464499)
- Testing
- ECG measurement
- Where
- 2 sites in France
- Volunteers
- 160 people
- Sponsor
- Withings
Low Back Pain, Neck Pain
The Role of Core and Functional Exercises in Low Back and Neck Pain
Low back and neck pain are common health problems that can negatively affect daily life activities in healthy women. A significant proportion of adults worldwide experience low back or neck pain at some point in their lives…
- Conditions
- Low Back Pain, Neck Pain, Core Exercises Training, Functional Exercise Training
- Trial name
- NCT07190898
- Testing
- core exercises, functional strength exercises, education group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Batman University
Hepatocellular Carcinoma
Fu Zheng Jie Du Hua Yu Principle For Treatment Of Severe HBV Related Hepatocellular Carcinoma (FZJDHYPFTOSHBVHCC)
The treatment of HBV related hepatocellular carcinoma has always been a worldwide problem. The aim of this study is to alleviate the progression of hepatitis B related hepatocellular carcinoma by the Chinese medicine "Fu Zheng…
- Trial name
- NCT05152498
- Testing
- Fu Zheng Jie Du Hua Yu therapy
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Beijing Ditan Hospital
Hypothermia; Anesthesia, Hypothermia Following Anesthesia
Can the SpotOn™ Zero-Heat-Flux-Thermometry Sensor Accurately Measure Core Temperature in Children?
The present study aims to assess the accuracy of the SpotOn™ Zero-heat-flux-thermometry sensor in measuring core temperature in the paediatric population in the perioperative period.
- Conditions
- Hypothermia; Anesthesia, Hypothermia Following Anesthesia, Children
- Trial name
- NCT03157609
- Testing
- Thermometry
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Esophageal Subepithelial Lesions
EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
This is a single-blinded randomized control trial trying to compare the effectiveness of diagnosis between two techniques employed in tissue sampling for subepithelial tumors (SETs) of the gastrointestinal tract.
- Trial name
- NCT02282111
- Testing
- 22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
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