Clinical trials: CORE
Inflammatory Bowel Disease (IBD), Ulcerative Colitis
A Study of Vedolizumab and Biologic Agents in Participants With Inflammatory Bowel Disease (IBD)
This is a non-interventional, retrospective study of adult participants with IBD. IBD consists of either ulcerative colitis (UC) or Crohn's disease (CD).
- Conditions
- Inflammatory Bowel Disease (IBD), Ulcerative Colitis, Crohn's Disease
- Trial name
- NCT05596422
- Where
- 4 sites in Taiwan
- Volunteers
- 423 people
- Sponsor
- Takeda
Breast Cancer
Comparison Trial of Open-tip Pulsed Needle Biopsy and Conventional Core Biopsy in Axillary Lymph Nodes
The aim of the study is to compare performance and safety of a newly developed 14-gauge open-tip pulsed biopsy needle with a conventional 14-gauge core biopsy needle for sampling of radiologically indeterminate or suspicious…
- Trial name
- COMPULSE (NCT04500262)
- Testing
- Open-tip pulsed needle biopsy (NeoNavia Biopsy System), Core needle biopsy (CNB)
- Where
- 16 sites in United Kingdom
- Volunteers
- 479 people
- Sponsor
- NeoDynamics AB
Sarcopenia, Muscle Weakness
Foot Core Exercise Program on Balance Control and Walking in Aged Sarcopenia
In modern society with an increasing aging population, recent literature has defined sarcopenia as a significant reduced mass and function of skeletal muscle with physical limitations due to aging.
- Conditions
- Sarcopenia, Muscle Weakness, Walking, Difficulty, Balance Control
- Trial name
- NCT05750888
- Testing
- integrated exercise therapy with 3D printing exerciser for training intrinsic foot muscles, regular exercises for the elderly
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Athletic Performance
Effect of Instability Resistance Training on Balance, Core Muscle Strength, and Athletic Performance
The goal of this experimental study is to examine the effect of instability resistance training (IRT) on balance ability, core muscle strength, and athletic performance of young Chinese male kayak canoeists.
- Trial name
- NCT06432595
- Testing
- Instability resistance training and Traditional resistance training
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Low Back Pain, Chronic
Additional Effects of Retro Walking.
The aim of this study is to find the effects of retro walking along with core stabilization on pain, disability and balance in non-specific chronic low back pain patients.
- Trial name
- NCT07484542
- Testing
- Retro walking and Core stabilization, Core Stabilization
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Chronic Plantar Fasciitis, Functional Hallux Limitus
Effect of Foot Core Control Training on Dorsiflexion Function and Gait Biomechanical Characteristics of Patients With Chronic Plantar Fasciitis
The pain and abnormal gait postures observed in CPF patients may be associated with impaired foot function. However, few studies have examined the dorsiflexion function of the big toe in CPF patients, and the effectiveness of…
- Trial name
- NCT07182201
- Testing
- Foot core control training, CPF Conventional training
- Volunteers
- 34 people
- Sponsor
- Peking University Third Hospital
Hepatitis B
Activation of Hepatitis B Virus (HBV) in Hepatitis B Surface Antigen (HBsAg) - Negative But Hepatitis B Core Antibody (Anti-HBc) - Positive Patients
Individuals with resolved hepatitis B, characterized as hepatitis B surface antigen (HBsAg)-negative and hepatitis B core antibody-positive, have latent hepatitis B virus (HBV) infection in their liver tissue.
- Trial name
- NCT00881036
- Where
- Japan
- Volunteers
- 33 people
- Sponsor
- Kyoto University
Coronary Atherosclerosis, Myocardial Infarction
CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow
The CANARY (Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow) Study is a pivotal trial to evaluate criteria for defining a Lipid Core Plaque (LCP) that is at high risk of rupturing during standard of…
- Conditions
- Coronary Atherosclerosis, Myocardial Infarction, Coronary Plaque Embolization
- Trial name
- CANARY (NCT01268319)
- Testing
- Embolic Protection Device (EPD), Intracoronary Spectroscopy and Ultrasonic Evaluation, Angioplasty and Stent Implant
- Where
- 9 sites in United States
- Volunteers
- 85 people
- Sponsor
- Infraredx
Heart Murmurs
: A Prospective Study Investigating the Use of the Eko CORE and Eko DUO Electronic Stethoscopes in Pediatric Patients.
The Eko CORE and DUO stethoscopes are FDA approved electronic devices which have the capacity to record heart sounds. This study will utilize these devices to see if they can differentiate between pathologic and innocent heart…
- Trial name
- NCT04317521
- Testing
- Use of EKO Core and EKO Duo electronic stethoscopes
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Patients Scheduled for Brain Surgery
Effect of Heated Breathing Circuit on Intraoperative Core Temperature and Systemic Inflammation After Brain Surgery: a Prospective Randomized Study
Mechanical respiration during general anesthesia causes cold and dry gases to reach the lower airway, reduce the function of the airway mucosa, and cause accumulation of secretions.
- Trial name
- NCT03491332
- Testing
- conventional circuit, conventional humidification circuit, new humidifaction heat circuit
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Yonsei University
Tai Ji
The Comparisons of Effects of Core Stability Exercise and Tai Chi on Core Muscle Performances in Elderly
Core muscles and core stability has a key component in the postural control or balance. However, no clear evidence has been found for the positive relationship between core stability and postural control in the elderly, and the…
- Trial name
- NCT04887363
- Testing
- Core exercise, Tai Chi exercise
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Chronic Low-back Pain
Myofascial Trigger Point Release and Paced Breathing Training for Chronic Low Back Pain
A study to explore whether two different treatment approaches, myofascial trigger point release and core stabilization exercises, both with and without additional paced breathing training, can help patients with chronic low back…
- Trial name
- NCT04107597
- Testing
- Core stabilization exercises, Core stabilization exercises and paced breathing training, Myofascial trigger point release
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Metastatic Melanoma, Skin Cancer
Cryoablation+Ipilimumab+Nivolumab in Melanoma
The aim of this study is to find out whether the combination of two approved drugs, ipilimumab and nivolumab, in combination with cryoablation are safe and effective for participants who have an unresectable melanoma that is…
- Trial name
- NCT05779423
- Testing
- Ipilimumab, Nivolumab, Cryoablation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Massachusetts General Hospital
Neck Pain Musculoskeletal, Back Pain
Diaphragmatic Breathing Exercises and Chronic Non-spesifik Neck and Back Pain
Effects of Diaphragmatic Breathing Exercises Added to Posture and Core Stabilization Training on Pain, Body Awareness and Cardiovascular Parameters in Women with Chronic Non-spesific Neck and Back Pain
- Trial name
- NCT07683273
- Testing
- Diapragmatic Breathing, Control Group (A):
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Cerebral Palsy
Effects of Modified Pilates Exercises on Body Control, Gait and Function in Children With Cerebral Palsy
Children with cerebral palsy (CP) have limitations in postural reactions and antigravity movements. Trunk control is the determinant of posture, balance, walking and functional activities.
- Trial name
- NCT04035954
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Sanko University
Disorders of Consciousness
The Core Body Temperature Rhythms: Distinguishing MCS From UWS
In this study, the core body temperature of 7 disorders of consciousness ( DOC ) patients were measured every 2 hour for 168 h .
- Trial name
- NCT02930213
- Volunteers
- 7 people
- Sponsor
- Jing Wang
Postural Low Back Pain
Comparison of Core Stabilization and Neuromuscular Facilitation Exercises for Lowback Pain Prevention
Low back pain (LBP) is a leading cause of disability worldwide, particularly affecting individuals in occupations that demand prolonged sitting or standing, such as healthcare professionals.
- Trial name
- NCT06846203
- Testing
- Core stabilization Exercise Group, Neuromuscular Fascilitation Exercise Group
- Where
- Pakistan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Functional Electrical Stimulation, Cerebral Palsy
Functional Electrical Stimulation With Core Stabilization Exercises in Children With Spastic Diplegia
This study was done to: investigate the combined effect of functional electrical stimulation with core stabilization exercises on pelvic tilting in children with spastic diplegia.
- Conditions
- Functional Electrical Stimulation, Cerebral Palsy, Core Stability
- Trial name
- NCT07110025
- Testing
- designed physical therapy program, core stabilization exercise with neuromuscular electrical stimulation
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Lumbar Spine Instability
Effects of Core Stabilization Exercise on Balance
Recent studies indicate that patients with chronic low back pain (LBP) present problems in balance. Alterations in proprioception are the possible causes of alteration of postural balance in LBP.
- Trial name
- NCT02200913
- Testing
- core stabilization exercise, general trunk strengthening exercise
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Diagnostic Self Evaluation
Diagnostic Efficiency of Touch Imprints Versus Smears
Cytopathologists work along with radiologist in the diagnosis of lesions. Rapid on site interpretation (ROSE) of fine needle aspiration (FNA) smears of radiologically suspicious lesions is a common clinical practice.
- Trial name
- NCT03224910
- Testing
- Cytologic techniques used for rapid on site interpretation
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
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