Clinical trials: CORE
Bloating, Distension
Investigation of the Relationship Between Core Muscles Functions and Symptoms of Patients with Abdominal Bloating/Distension
The aim of this study is to investigate the relationship between core muscle functions (strength, endurance, thickness) and symptoms in individuals with abdominal bloating/distension.
- Trial name
- NCT06659874
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Dokuz Eylul University
Lung Neoplasm
Correlation of X-ray and Pathology With Needle Biopsy of Lung Tumors
The purpose of this study is to compare the features that the pathologist sees, when examining a lung tumor under the microscope, to the way that the tumor appears on the computed tomography (CT) scan.
- Trial name
- NCT00638625
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Ovarian Cancer
A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles for Terminal Ovarian Cancer
To confirm the safety of 6 cycles of Perfusion Induced Systemic Hyperthermia (PISH) provided every 28 days in 3rd line ovarian cancer patients.
- Trial name
- PISH-2 (NCT02093871)
- Testing
- ThermalCore Hyperthermia System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ThermalCore Inc
Patellofemoral Osteoarthritis
Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study
The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap).
- Trial name
- NCT02825238
- Testing
- Supervised exercise program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Rheumatoid Arthritis
An Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients Completing Treatment in Tocilizumab Core Studies
This single-arm study evaluated the long-term efficacy and safety of tocilizumab in participants who had completed treatment in the tocilizumab core studies (NCT00106522 [Roche protocol WA18062], NCT00106574 [Roche protocol…
- Trial name
- NCT00720798
- Testing
- Tocilizumab, Disease-modifying anti-rheumatic drugs, Non-steroidal anti-inflammatory drugs
- Where
- 295 sites in United States, Argentina and 32 more
- Volunteers
- 2,067 people
- Sponsor
- Hoffmann-La Roche
Multiple Myeloma
A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody
Multiple myeloma (MM) is an incurable malignancy and accounts for 1 percentage (%) of all cancers and for 10% of all hematologic malignancies.
- Trial name
- NCT03525678
- Testing
- Belantamab mafodotin frozen liquid, Belantamab mafodotin lyophilized powder
- Where
- 59 sites in United States, Australia and 6 more
- Volunteers
- 221 people
- Sponsor
- GlaxoSmithKline
Body Temperature Regulation
Non-invasive Sensor for Core Temperature Measurement
Soldiers are required to perform and maintain alertness in difficult environmental conditions. The sensor examined in this trail may indicate body core temperature elevation during exertion.
- Trial name
- Drager (NCT02017184)
- Testing
- Noninvasive core temperature thermistor
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Acute Gout
Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use Non-steroidal Anti-inflammatory Drugs (NSAIDs) and/or Colchicine Including a 12 Weeks Extension and an Open-label 48 Weeks Extension Study
The purpose of the 12-week core study was to demonstrate that canakinumab given upon acute gout flares relieves the signs and symptoms and prevents recurrence of gout flares in patients with frequent flares of gout for whom…
- Trial name
- β-RELIEVED (NCT01029652)
- Testing
- Canakinumab 150 mg, Triamcinolone acetonide 40 mg
- Where
- 47 sites in Australia, Belgium and 15 more
- Volunteers
- 230 people
- Sponsor
- Novartis Pharmaceuticals
Lupus Erythematosus, Cutaneous, Lupus Erythematosus, Systemic
European Society of Cutaneous Lupus Erythematosus (EUSCLE)
Cutaneous lupus erythematosus (CLE) is a disease with a wide spectrum of clinical manifestations and a variable prognosis. The aim of the study is to create a standardized evaluation of the different subtypes of this disease in…
- Trial name
- NCT00420121
- Testing
- laboratory analysis
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- European Society of Cutaneous Lupus Erythematosus e.V.
Rectal Neoplasms
CORE: Capecitabine, Oxaliplatin, Radiotherapy and Excision
Primary objective: Pathological complete response (ypT0N0) rate Secondary objectives: Histopathological R0 resection rate Pathological downstaging (ypT0-T2N0) rate One month surgical complication rate Predictive value of…
- Trial name
- NCT00174616
- Testing
- Oxaliplatin, capecitabine, radiotherapy
- Where
- 7 sites in Belgium, France and 5 more
- Volunteers
- 87 people
- Sponsor
- Sanofi
Shoulder Injuries
Effects of Upper Limb PRT With CSE on Pain, Core Strength and ULB in Cricket Fast Bowlers With Shoulder Injury
Musculoskeletal pain and dysfunction, particularly in the upper limb and spine, are often linked to poor core stability and muscular imbalance.
- Trial name
- NCT07055685
- Testing
- Progressive Resistance Training + Core Stability Exercises, Progressive Resistance Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University
Breast Cancer
Accuracy of FNA Versus CNB of Abnormal Axillary Lymph Nodes in Setting of Invasive Breast Cancer
To compare accuracy of ultrasound guided fine needle aspiration (FNA) to core needle biopsy (CNB) of ultrasound detected abnormal axillary lymph nodes in patients with newly diagnosed invasive breast cancer or suspected invasive…
- Trial name
- NCT02019303
- Testing
- FNA and Core biopsy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Utah
Shoulder Pain, Scapular Dyskinesis
Shoulder Pain, Core Endurance, and Scapular Control in Adolescent Volleyball Players
Shoulder pain is one of the most common musculoskeletal problems in adolescent volleyball players because of repetitive overhead activities such as serving and spiking.
- Conditions
- Shoulder Pain, Scapular Dyskinesis, Core Endurance
- Trial name
- NCT07720050
- Testing
- Visual Analog Scale (VAS), Scapular Dyskinesis Test, McGill Core Endurance Test Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Breast Neoplasm
Prediction of pCR by Preoperative Biopsy in Breast Cancer With cCR After Neoadjuvant Chemotherapy.
The purpose of this study is to evaluate the ability of preoperative biopsy to predict correctly pathologic complete response in breast cancer patients with complete clinical response after neoadjuvant chemotherapy.
- Trial name
- NCT03273426
- Testing
- Minimally-invasive biopsy, wide excision
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Physical Endurance
Isometric Core Muscle Endurance in Healthy Active and Non-active Working Age Populations
Objectives: The purpose of this study was to investigate a possible correlation between core muscle endurance and participants' age in healthy adult population.
- Trial name
- NCT04209335
- Testing
- isometric core muscle endurance testing
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hanna Holmberg
Stroke
Core Stabilization Exercises in Stroke
A stroke due to a cerebrovascular accident (CVA) is a neurological deficit characterized by the rapid settlement of signs and symptoms due to focal or global loss of cerebral function, without any apparent cause other than…
- Trial name
- NCT05549518
- Testing
- Core stabilization + Traditional Physical Therapy, Traditional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Biruni University
Archery, Physiotherapy and Rehabilitation
The Effect of Neuroscience-Based Exercise Training on Shooting Performance and Neuromuscular Performance in Archers
Archery is a sport that demands sport-specific motor performance, emphasizing fine motor control, postural stability, balance, and concentration skills.
- Conditions
- Archery, Physiotherapy and Rehabilitation, Muscle Activity, Visual Rehabilitation
- Trial name
- NCT07051577
- Testing
- Exercise Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Istinye University
Breast Cancer
Comparison Trial of Open-tip Pulsed Needle Biopsy and Conventional Core Biopsy in Axillary Lymph Nodes
The aim of the study is to compare performance and safety of a newly developed 14-gauge open-tip pulsed biopsy needle with a conventional 14-gauge core biopsy needle for sampling of radiologically indeterminate or suspicious…
- Trial name
- COMPULSE (NCT04500262)
- Testing
- Open-tip pulsed needle biopsy (NeoNavia Biopsy System), Core needle biopsy (CNB)
- Where
- 16 sites in United Kingdom
- Volunteers
- 479 people
- Sponsor
- NeoDynamics AB
Exercise, Muscle Weakness
The Effect of Core Stability Exercises on Pain, Muscle Strength, and Muscle Architecture in Tennis Players With Rotator Cuff Lesions
This study aims to shed light on the supraspinatus and infraspinatus muscles, which play a significant role in rotator sheath tendinopathy and tears.
- Conditions
- Exercise, Muscle Weakness, Rotator Cuff Injuries
- Trial name
- NCT06402162
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara University
Healthy Children
Fine Motor Performance in School-aged Children
The goal of this observational cross-sectional study is to investigate the relationship between core stability, hand grip strength, and handwriting performance in typically developing school-aged children aged 8 to 12 years.
- Trial name
- HGS/HLS (NCT07767656)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
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