Clinical trials: CORE
Cancer, Coronary Artery Disease
Calibration of MR and PET-MR Imaging Protocols at RIC
This is a protocol to facilitate on-site calibration of the technical aspects of the Siemens Biograph mMR (molecular MR) Positron Emission Tomography-Magnetic Resonance (PET-MR) scanner and the 3T Siemens Vida MR scanner at the…
- Trial name
- NCT02249520
- Testing
- PET-MR imaging on Biograph mMR scanner, MR-only imaging on Biograph mMR scanner, MR imaging on the Siemens Vida 3T MR scanner
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Heart Failure, Sudden Cardiac Death
CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation
The Medtronic InSync III Marquis Cardiac Resynchronization Therapy Defibrillator (CRT-D)-System (implantable cardioverter-defibrillator with biventricular stimulation for cardiac resynchronization) is equipped with the…
- Conditions
- Heart Failure, Sudden Cardiac Death, Atrial Fibrillation
- Trial name
- NCT00170313
- Testing
- Conducted AF-Response Algorithm (CAFR) On, Conducted AF-Response Algorithm (CAFR) Off
- Where
- 7 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Chronic Stroke
Effects of Core Strengthening and PNF Pattern on Static Balance and Plantar Pressure in Chronic Stroke Patients
Stroke is a neurological disease characterized by neurological deficits caused by insufficiency of blood supply to brain. Disruption of blood supply to brain can be due to blockage of blood supply (ischemic) or leakage of blood…
- Trial name
- NCT06346652
- Testing
- Routine Physical Therapy, Routine Physical Therapy+ PNF and Core Stregthening
- Where
- Pakistan
- Volunteers
- 73 people
- Sponsor
- University of Lahore
Cerebral Palsy
Effects of Core Stability Program on Abdominal Endurance in Wheelchair Bound Cerebral Palsy
This study aims to evaluate the effects of a Core Stability Program on abdominal endurance and constipation severity in wheelchair-bound children with cerebral palsy.
- Trial name
- NCT07764952
- Testing
- Core Stability Program, traditional Physiotherapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Postpartum, Diastasis Recti Abdominis (DRA)
Comparative Effects of Telerehabilitation Versus In-Person Core Stability Training in Postpartum Women
Diastasis recti abdominis (DRA) is common among postpartum women and can negatively affect abdominal muscle function and body image.
- Trial name
- NCT07751952
- Testing
- Telerehabilitation, In-Person
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Cystic Fibrosis
Cystic Fibrosis Core Strengthening and Respiratory Exercise Program
The purpose of this project is to determine the short-term effects of a customized Core Strengthening and Respiratory Exercise Program (CSREP) on children with cystic fibrosis (CF) between the ages of 10 and 21 who are receiving…
- Trial name
- CSREP (NCT00751647)
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS)
This Study Aimed to Evaluate the Effect of Dynamic Neuromuscular Stabilization (DNS) on Pain Intensity and Functional Disability in Women With PLBP as Common Problem Affect t he Women After Birth Which Often Impacting Their Quality of Life and Ability to Perform Daily Activities
The aim of this study was to determine the effect of DNS on women with post-partum LBP. Post-partum low back pain (PLBP) represents a prevalent and clinically significant condition that adversely impacts mobility, pelvic floor…
- Conditions
- Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS), Women's Health / Physiotherapy, Musculoskeletal Rehabilitation
- Trial name
- NCT07099755
- Testing
- Intervention Group: Name: Dynamic Neuromuscular Stabilization (DNS) Exercises, Control Group:Name: Conventional Physiotherapy (Ultrasound and Infrared Therapy)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gehad Alaa
Strain of Fascia of Intrinsic Muscle of Foot (Disorder), Elastography
Integrated Exercise Therapy Interventions on the Performance and Injury Prevention in Competitive Sports
Football is an increasingly popular exercise and common practice among adolescent and elite athletes. However, these athletes tend to have injuries involving the lower extremity and foot.
- Conditions
- Strain of Fascia of Intrinsic Muscle of Foot (Disorder), Elastography, Muscle Weakness
- Trial name
- NCT04384003
- Testing
- Shear Wave Ultrasound Elastography, The 3-D Motion Analysis, Electromyographic
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Weight Management
CORE Study - Research Into Weight Management Services in the UK
Weight management services (previously known as Tier 3 services) represent a multidisciplinary specialist approach, available in community or secondary care settings.
- Trial name
- CORE (NCT07559409)
- Where
- United Kingdom
- Volunteers
- 41,000 people
- Sponsor
- Society for Endocrinology
Stroke
Combined Effects of Motor Imagery and Core Stability Exercises in Stroke Patients
This research explores the combined effects of motor imagery and core stability exercises on trunk control, balance, and sleep quality in stroke recovery, addressing Pakistan's unique healthcare challenges.
- Trial name
- NCT06696911
- Testing
- Core stability Exercises, Motor Imagery
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Riphah International University
PERFORMANCE, VERTICAL JUMP PERFORMANCE
Neuromuscular Predictors Of Vertical Jump Performance in National-Team Wrestlers
The study will include national wrestlers studying at Kırşehir Ahi Evran University School of Physical Education and Sports who meet the inclusion criteria and agree to participate.
- Trial name
- NCT07750691
- Testing
- Neuromuscular performance assessment protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Amphetamine Use Disorders
Closed-loop cTBS for the Core Clinical Features of Methamphetamine Use Disorder
Using specific EEG biomarkers in methamphetamine-dependent individuals, this study systematically probes closed-loop continuous Theta-burst Stimulation (cTBS) based on brain states, assessing dosage, neurologic and behavioral…
- Trial name
- NCT06457243
- Testing
- Closed-loop cTBS stimulation based on addiction induced states
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Multiple Myeloma
A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody
Multiple myeloma (MM) is an incurable malignancy and accounts for 1 percentage (%) of all cancers and for 10% of all hematologic malignancies.
- Trial name
- NCT03525678
- Testing
- Belantamab mafodotin frozen liquid, Belantamab mafodotin lyophilized powder
- Where
- 59 sites in United States, Australia and 6 more
- Volunteers
- 221 people
- Sponsor
- GlaxoSmithKline
Colorectal Cancer, Breast Cancer
Feasibility Study of Genomic Profiling Methods and Timing in Tumor Samples
This is a feasibility study to look for genetic alterations in tissue and blood samples that may be useful in determining what treatments may be useful in the patient's cancer care.
- Conditions
- Colorectal Cancer, Breast Cancer, Gynecological Cancer, Metastatic
- Trial name
- NCT01703585
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University Health Network, Toronto
Sports Physical Therapy
Comparison of Pilates and Traditional Plank in Recreational Badminton Players.
To compare the effects of Pilates exercise and traditional plank exercise training on core muscle strength, balance and agility in recreational badminton players
- Trial name
- NCT05060081
- Testing
- Pilates exercise program group, Traditional plank exercise program group
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
AVN
Hyperbaric Oxygen Therapy Versus Core Decompression Augmented With Bone Substitute in Pre Collapse of Avascular Necrosis of Femoral Head
Introduction: osteonecrosis of the femoral head is a potentially crippling disorder, which mainly affects the young adults. Core decompression has been used for the treatment of the osteonecrosis of the femur head since was…
- Trial name
- NCT04657653
- Testing
- core decompression
- Where
- Qatar
- Volunteers
- 19 people
- Sponsor
- Hamad Medical Corporation
Low Back Pain
Cross Culture Adaptation and Validation of the Arabic Version of COMI in Patients With Low Back Pain
This study aims at translating, cross culturally adapting and establishing the psychometric properties of the The Core Outcome Measure Index (COMI) for patients with low back pain (LBP) in Egypt.
- Trial name
- NCT03328806
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Aliaa Rehan Youssef
Coronary Artery Disease
A Safety and Efficacy of Supralimus™ Core™ Sirolimus Eluting Stent at MAX DDHV Institute
OBJECTIVES: The primary objective of this study is to assess the safety and efficacy of the Supralimus - Core™ Sirolimus Eluting Stent in de novo native vessel obstructive coronary artery disease.
- Trial name
- Maximus (NCT00811616)
- Testing
- Supralimus-Core™, Supralimus™ Core™ Sirolimus eluting stent
- Where
- India
- Volunteers
- 105 people
- Sponsor
- Sahajanand Medical Technologies Limited
Biological Markers, Diet, Healthy
Dietary Biomarkers Intervention Core
The purpose of this controlled feeding trial is to establish an Intervention Core, equipped to perform tightly controlled pharmacokinetic (PK) and dose-response (DR) feeding studies.
- Conditions
- Biological Markers, Diet, Healthy, Metabolomics, Nutrition, Healthy
- Trial name
- NCT05616585
- Testing
- Pharmacokinetic (PK)- Controlled Feeding Diet, Dose Response (DR)- Controlled Feeding Diet
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Prematurity, Respiratory Disease
Prematurity and Respiratory Outcomes Program (PROP)
In survivors of extreme prematurity to 36 weeks Post Menstrual Age (PMA), specific biologic, physiologic and clinical data obtained during the initial hospitalization will predict respiratory morbidity as defined by respiratory…
- Trial name
- PROP (NCT01435187)
- Where
- 13 sites in United States
- Volunteers
- 835 people
- Sponsor
- University of Pennsylvania
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