Clinical trials: COVID-19 Pneumonia
Covid19, Critical Illness
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training after COVID-19 critical illness (REMM-HIIT-COVID-19)
- Conditions
- Covid19, Critical Illness, High Intensity Interval Training, ICU
- Trial name
- REMMHIIT-COVID (NCT04664101)
- Testing
- REmotely Monitored, Mhealth (REMM) supported High Intensity Interval Training (HIIT), Comparator
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Duke University
COVID, COVID19
International SARS-CoV-2 (COVID-19) Infection Observational Study
The general aim of this study is to estimate the rate of disease progression for adults testing positive for SARS-CoV-2. The primary endpoint for this study and the basis for sample size is hospitalization or death during the 28…
- Conditions
- COVID, COVID19, SARS-CoV 2, Dyspnea
- Trial name
- ICOS (NCT04385251)
- Testing
- Data Collection
- Where
- 4 sites in United States, Argentina and 2 more
- Volunteers
- 11,973 people
- Sponsor
- University of Minnesota
SARS-CoV-2 Infection, COVID-19
Index Individuals in SARS-CoV-2 Prevention Research Studies (COVID-19 Index Individuals Companion Study)
Clinical trials of prevention modalities for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and coronavirus disease (COVID-19) and pneumonia are underway under separate protocol(s) for close contacts…
- Conditions
- SARS-CoV-2 Infection, COVID-19, Coronavirus Infection, SARS (Severe Acute Respiratory Syndrome)
- Trial name
- IICov19PRS (NCT05074719)
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- University of Washington
COVID-19 Pandemic
The Immunogenicity and Safety of V-01-351/V-01D Bivalence Vaccine
It is a Single Arm, Open Label Clinical Study to Evaluate the Immunogenicity and Safety of Sequential Immunization of V-01-351/V-01D Bivalence Vaccine in Healthy Adults Aged 18 Years and Older After the Vaccination of 2 Doses of…
- Trial name
- Omicron (NCT05273528)
- Testing
- Recombinant SARS-CoV-2 Beta Variant Fusion Protein Vaccine/Recombinant SARS-CoV-2 Delta Variant Fusion Protein Vaccine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Livzon Pharmaceutical Group Inc.
Healthcare Worker, Covid19
A Research Platform to Screen Healthcare Workers- Coordinated Approach to Pandemic Trials of COVID-19
Recent studies have shown that some individuals may be asymptomatic but continue to shed the COVID-19 virus. These individuals may represent a population that can unknowingly transmit the virus.
- Trial name
- RESPECT (NCT04574765)
- Testing
- Nasopharyngeal swab, Questionnaire collection (CITF), Optional blood collection
- Where
- Canada
- Volunteers
- 7,373 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Covid19
Impact of GSE and Xylitol (Xlear) on COVID-19 Symptoms and Time to PCR Negativisation in COVID-19 Patients
This clinical trial aims to ascertain the impact of GSE and Xylitol (XLEAR) in decreasing the time of negativisation in PCR testing in patients with COVID-19.
- Trial name
- NCT04854486
- Testing
- GSE and Xylitol
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Larkin Community Hospital
COVID-19, Pneumonia
Low-Dose Radiation Therapy to Lungs in Moderate COVID-19 Pneumonitis: A Case-Control Pilot Study
This pilot case-control study at Mahatma Gandhi Institute of Medical Sciences (MGIMS), Sevagram, India is designed to evaluate the use of low dose radiotherapy (LDRT) in patients with moderate COVID-19 with specific objectives to…
- Trial name
- LOCORAD (NCT04904783)
- Testing
- Low dose radiotherapy
- Where
- 2 sites in India
- Volunteers
- 20 people
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
COVID-19, Anxiety
Coronavirus Anxiety in Patients Using Biologic vs Conventional DMARDs
The COVID-19 pandemic has caused significant psychological distress among patients with chronic diseases. Individuals receiving immunosuppressive therapies may experience increased anxiety due to perceived vulnerability to…
- Conditions
- COVID-19, Anxiety, Rheumatic Diseases
- Trial name
- NCT07436494
- Testing
- Current treatment (no intervention assigned)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa City Hospital
COVID-19, Coronavirus Infection
Study to Evaluate the Effect of a Probiotic in COVID-19
A prospective case-control pilot study to evaluate the possible effect of a probiotic mixture in the improvement of symptoms, the reduction in the number of days of hospitalization and the increase in the percentage of patients…
- Trial name
- NCT04390477
- Testing
- Probiotic
- Where
- 2 sites in Spain
- Volunteers
- 41 people
- Sponsor
- Bioithas SL
Covid19, Burn Out
Burnout and Distress preventiOn With caNnabidiol in Front-line Health Care workerS deAling wIth COVID-19
The objective of this work is to monitor the level of stress and overload of a group of front-line health workers (physicians, nurses and physiotherapists) who will participate in the care of patients with COVID-19 at Hospital…
- Conditions
- Covid19, Burn Out, Post Traumatic Stress Disorder
- Trial name
- BONSAI (NCT04504877)
- Testing
- Cannabidiol
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
COVID-19
Crowdsourcing an Open COVID-19 Imaging Repository for AI Research
The objectives of this project are to (1) assemble a crowdsourced, de-identified radiographic repository; and (2) train and validate existing COVID-NET deep learning diagnostic models.
- Trial name
- NCT05384912
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Covid-19 Infection
Awake Pronation for Covid-19 Treatment
Observational studies have shown that prone position (PP) in spontaneously breathing patients, may improve oxygenation in individuals with Acute Respiratory Failure (ARF), due to Covid-19 infection.
- Trial name
- NCT04667286
- Testing
- Prone Position (PP)
- Where
- 3 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
SARS-CoV2, COVID
Prognostication of Oxygen Requirement in Non-severe SARS-CoV-2 Infection
Note that this is a study that is co-sponsored by Medecins Sans Frontieres, Spain, and the University of Oxford. The primary objective of this study is to identify clinical and biochemical prognostic markers in adults with…
- Trial name
- PRIORITISE (NCT04441372)
- Where
- 3 sites in Brazil, India
- Volunteers
- 600 people
- Sponsor
- Medecins Sans Frontieres, Spain
COVID-19 Pneumonia
Pilot Study of Cefditoren Pivoxil in COVID-19 Patients With Mild to Moderate Pneumonia
The global pandemic of novel coronavirus disease 2019 (COVID-19) began in Wuhan, China, in December 2019, and has since spread worldwide.
- Trial name
- NCT04709172
- Testing
- Cefditoren pivoxil 400mg
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Meiji Pharma Spain S.A.
Covid19
Off-the-shelf NK Cells (KDS-1000) as Immunotherapy for COVID-19
It is hypothesized that immunotherapy with off-the-shelf NK cells (KDS-1000) early in the course of COVID-19 disease is safe and may augment innate immunity, thereby limiting disease progression and improving survival.
- Trial name
- NCT04797975
- Testing
- KDS-1000
- Sponsor
- Kiadis Pharma
COVID-19
Therapy for Pneumonia Patients iInfected by 2019 Novel Coronavirus
The 2019 novel coronavirus pneumonia outbroken in Wuhan, China, which spread quickly to 26 countries worldwide and presented a serious threat to public health.
- Trial name
- NCT04293692
- Testing
- UC-MSCs
- Where
- China
- Sponsor
- Puren Hospital Affiliated to Wuhan University of Science and Technology
Coronavirus Infection
Prevalence and Incidence of COVID-19 Infection in Patients With Chronic Plaque Psoriasis on Immunosuppressant Therapy
This study will assess the prevalence and incidence of COVID-19 infection in patients with chronic plaque psoriasis on immunosuppressant therapy.
- Trial name
- NCT04324866
- Testing
- Nasopharyngeal swab
- Volunteers
- 300 people
- Sponsor
- Universita di Verona
Covid19
Covid-19 Messaging to Underserved Communities - 2nd Experiment
The aim of the study is to build off results from our first experiment (NCT04371419) , and test whether messages that acknowledge racial injustice on behalf of institutions affect the retention of knowledge and movement of…
- Trial name
- NCT04502056
- Testing
- Acknowledgement Racial Injustice AMA, African American Sender Acknowledgement, African American Sender in Informational Videos.
- Where
- United States
- Volunteers
- 20,460 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Cardiovascular Diseases
Clinical and Imaging Biomarkers Associated With Plasma ad Cellular Determinants of Cardiovascular Disease at the Time of COVID 19
Acute and chronic cardiovascular complications of pneumonia are common and result from various mechanisms, including relative ischemia, systemic inflammation, and pathogen-mediated injury.
- Trial name
- CARDIOCOVID (NCT05745753)
- Testing
- sample blood
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
COVID-19, Liver Disease
Effectiveness and Safety of the COVID-19 Vaccination for Patients With Liver Disease (CHESS2101)
COVID-19 pandemic with SARS-CoV-2 infection has become a global challenge. Though most cases of COVID-19 are mild, the disease can also be fatal.
- Conditions
- COVID-19, Liver Disease, Vaccine Reaction
- Trial name
- NCT04883177
- Where
- 37 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
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