Clinical trials: COVID-19 Pneumonia
Systemic Lupus Erythematosus, COVID-19
Lupus Education Alliance Program
Randomized controlled trial of a COVID-19 behavioral and educational intervention for people with systemic lupus erythematosus (SLE).
- Trial name
- LEAP (NCT05243875)
- Testing
- LEAP Education + Navigation, LEAP Education
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Tulane University
COVID-19
Desidustat in the Management of COVID-19 Patients
This study is a Phase 2b, Multicenter, Open-label, Randomized, Comparator- Controlled Study to Evaluate the Efficacy and Safety of Desidustat Tablet for the Management of mild, moderate and severe COVID-19 patients.
- Trial name
- NCT04463602
- Testing
- Desidustat, Standard of Care
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- Zydus Lifesciences Limited
COVID-19
Vitamin D and Zinc Supplementation for Improving Treatment Outcomes Among COVID-19 Patients in India
The purpose of this study is to assess the effect of vitamin D and/or zinc supplementation on improving COVID-19 treatment outcomes.
- Trial name
- NCT04641195
- Testing
- Vitamin D3 (cholecalciferol), Zinc (zinc gluconate), Zinc (zinc gluconate) & Vitamin D (cholecalciferol)
- Where
- 2 sites in India
- Volunteers
- 181 people
- Sponsor
- Harvard School of Public Health (HSPH)
Covid19, Convalescence
Convalescent Plasma Therapy in Severe COVID-19 Infection
As of March 18, 2020, COVID-19 cases were reported in approximately 195 countries. No specific therapeutic agents or vaccines for COVID-19 are available.
- Trial name
- NCT04403477
- Testing
- Convalescent plasma
- Where
- Bangladesh
- Volunteers
- 20 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Respiratory Failure, COVID-19
Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization
Acute respiratory distress syndrome (ARDS) is a major complication among patients with severe disease. In a report of 138 patients with COVID-19, 20% developed ARDS at a median of 8 days after the onset of symptoms, with 12.3% of…
- Trial name
- PAPR (NCT04368000)
- Testing
- Intermittent prone positioning instructions, Usual care positioning with no instructions
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Covid19, Azithromycin
Proactive Care of Ambulatory COVID19 Patients
On January 9, 2020, a new emerging virus was identified by WHO as being responsible for grouped cases of pneumonia in China. It is a coronavirus, SARS-CoV-2, responsible for the disease COVID-19 (Coronavirus disease).
- Conditions
- Covid19, Azithromycin, Ambulatory
- Trial name
- AMBU-COVID (NCT04371107)
- Testing
- consultation, Azithromycin
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Mechanical Ventilation Complication, Hypoxemia
Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure
To determine whether a strategy of adding venovenous ECMO to mechanical ventilation, as compared to mechanical ventilation alone, increases the number of intensive care free days at day 60, in patients with moderate to severe…
- Conditions
- Mechanical Ventilation Complication, Hypoxemia, Acute Respiratory Distress Syndrome Due to COVID-19, COVID-19 Respiratory Infection
- Trial name
- REDEEM (NCT05562505)
- Testing
- Venovenous ECMO
- Where
- 7 sites in Australia, Germany
- Volunteers
- 140 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Continuous Renal Replacement Therapy, Pulmonary Edema
C2Rx Hemofiltration Treatment in Severe or Critically Ill Adults With COVID-19
The clinical trial will evaluate the short term and extended impact on on respiration, pulmonary function and cardiovascular function in C2Rx treatment verse Standard of Care (SOC) in critically ill adults with COVID-19…
- Conditions
- Continuous Renal Replacement Therapy, Pulmonary Edema, COVID-19
- Trial name
- NCT04537975
- Testing
- C2Rx, Standard of Care (SOC)
- Sponsor
- SeaStar Medical
Acute Lung Injury (ALI) Associated With COVID-19, Lung Inflammation Associated With COVID-19
TD-0903 for ALI Associated With COVID-19
This Phase 2 study will evaluate the efficacy, safety, pharmacodynamics and pharmacokinetics of inhaled TD-0903 compared with a matching placebo in combination with standard of care (SOC) in hospitalized patients with confirmed…
- Trial name
- NCT04402866
- Testing
- TD-0903
- Where
- 24 sites in United States, Brazil and 5 more
- Volunteers
- 235 people
- Sponsor
- Theravance Biopharma
Covid-19
CT Biomarkers Identification by Artificial Intelligence for COVID-19 Prognosis
The study hypothesis is that low-dose computed tomography (LDCT) coupled with artificial intelligence by deep learning would generate imaging biomarkers linked to the patient's short- and medium-term prognosis.
- Trial name
- COVID 19-IA (NCT04418245)
- Testing
- Imaging by thoracic scanner
- Where
- 6 sites in France, Martinique
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Malignant Lymphoma, Clinical Trial
A Real-World Study of COVID-19 Infection in Patients With Malignant Lymphomas Participating in Clinical Trials
This study focuses on the population of malignant lymphoma patients who are also in clinical research. Through a real world cross-sectional survey of infection and death risk during the COVID-19 pandemic in Guangzhou from…
- Conditions
- Malignant Lymphoma, Clinical Trial, COVID-19
- Trial name
- NCT05827341
- Testing
- No intervention
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Sun Yat-sen University
Novel COVID-19-Infected Pneumonia
An Efficacy and Safety Study of Jaktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pneumonia
This study adopts a randomized, double-blind, placebo parallel control design, and is expected to include 120 eligible patients with severe novel coronavirus pneumonia.
- Trial name
- NCT05686629
- Testing
- Jaktinib hydrochloride tablets
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
COVID-19 Pneumonia
Multiparametric Assessment of Peripheral Blood and Tissue Myeloid Cells. Phenotype for Precision Medicine in Patients With SARS-Cov-2 Infection
We hypothesise that patients with SARS-Cov-2 infection are characterized by progressive changes in distribution of distinct lung macrophages populations mediated by influx of circulating monocytes into the lungs .
- Trial name
- NCT05767853
- Testing
- Immune-phenotyping of tissue and peripheral blood myeloid compartment
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
COVID-19
FLARE: Favipiravir +/- Lopinavir: A RCT of Early Antivirals
The current pandemic of SARS-CoV-2 causing COVID-19 disease is an unprecedented global emergency. COVID-19 appears to be a disease with an early phase where the virus replicates, coinciding with first presentation of symptoms…
- Trial name
- FLARE (NCT04499677)
- Testing
- Favipiravir, Lopinavir/ Ritonavir
- Where
- 2 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- University College, London
Coronavirus, Covid19
NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis
The purpose of the research is to test out a new form of treatment that examines stimulation of a nerve in the participant's ear.
- Trial name
- NCT04638673
- Testing
- Soterix taVNS model 0125-LTE Stimulator - Active-Active Group
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medical University of South Carolina
Covid 19 Disease
Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate to Severe Covid 19 Disease
The investigator will select participants with moderate to severe covid 19 disease admitted in Fatima memorial hospital. The investigator will divide them in two groups according to convenience sampling.
- Trial name
- covid19 (NCT04603729)
- Testing
- Dexamethasone 2 MG/ML, Methylprednisolone Injection
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fatima Memorial Hospital
Colorectal Carcinoma, COVID 19
Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer
The goal of this observational study is to assess the impact of the COVID-19 pandemic on colorectal cancer (CRC) outcomes, particularly focusing on stage distribution and recurrence-free survival in patients undergoing surgery at…
- Trial name
- NCT06638957
- Where
- South Korea
- Volunteers
- 14,951 people
- Sponsor
- In Ja Park
Covid19
Immunohematology in COVID-19 Patients: A Hospital-based Retrospective Cohort Study
This is a hospital-based retrospective cohort study and the Immunohematologic characteristics of COVID-19 patients will be investigated systematically.
- Trial name
- NCT04932954
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- LI YAN
Novel Coronavirus Pneumonia
Clinical Trial Scheme of Tanreqing Capsules in the Treatment of COVID-19
This study was conducted in a randomized, double-blind, placebo-controlled, multicenter clinical trial design. Two groups were designed, the experimental group and the placebo control group.
- Trial name
- NCT05305456
- Testing
- Tanreqing capsule, Tanreqing capsule simulator
- Where
- 2 sites in China
- Volunteers
- 480 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
COVID-19
Isotretinoin in Treatment of COVID-19
Contributors: Lamia Elgarhy, Sabah El-Gaeish 1, Eman Hamed 2 , Wagdy Fathy2 Department of Dermatology, Department of Pharmacology1 , Faculty of Medicine, Tanta University, Department of Chest, Faculty of Medicine, Suez Canal…
- Trial name
- Randomized (NCT04361422)
- Testing
- Isotretinoin Only Product in Oral Dose Form
- Volunteers
- 300 people
- Sponsor
- Tanta University
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