Clinical trials: COVID-19 Pneumonia
COVID-19 Respiratory Infection, Viral Pneumonia
Study of the Use of the Drug Ingaron in Patients With COVID-19
Interferon gamma is a powerful endogenous regulatory cytokine that activates the antiviral immune response, while it also has its own antiviral activity.
- Trial name
- NCT05386459
- Testing
- Interferon Gamma
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- SPP Pharmaclon Ltd.
COVID-19
Hydroxychloroquine vs. Azithromycin for Outpatients in Utah With COVID-19
This study will compare two drugs (hydroxychloroquine and azithromycin) to see if hydroxychloroquine is better than azithromycin in treating outpatients with suspected or confirmed COVID-19.
- Trial name
- HyAzOUT (NCT04334382)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- 2 sites in United States
- Volunteers
- 1,550 people
- Sponsor
- Intermountain Health Care, Inc.
Post Acute COVID-19 Syndrome, Long COVID
Safety, Tolerability and Efficacy of S-1226 in Post-COVID-19 Subjects With Persistent Respiratory Symptoms.
This is a randomized (1:1) , placebo-controlled phase II study to evaluate the safety, tolerability and efficacy of S-1226 in Post-COVID-19 subjects (n≤48) with persistent respiratory symptoms.
- Conditions
- Post Acute COVID-19 Syndrome, Long COVID, COVID-19 Respiratory Infection
- Trial name
- NCT04949386
- Testing
- S-1226 (8%)
- Volunteers
- 48 people
- Sponsor
- SolAeroMed Inc.
SARS-CoV-2
A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants
This is an open-label study to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1273 Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) vaccine in adults with a kidney or liver solid organ transplant (SOT)…
- Trial name
- NCT04860297
- Testing
- mRNA-1273
- Where
- 15 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID-19, SARS CoV 2 Infection
STREngthening COronavirus Disease 2019 (COVID-19) Surveillance in Africa
The aim of this observational study was to develop, with the intended users, an epidemic surveillance and response system that will be effective, sensitive, coordinated and appropriate.
- Conditions
- COVID-19, SARS CoV 2 Infection, COVID-19 Pandemic
- Trial name
- STREESCO (NCT06170320)
- Where
- Benin
- Volunteers
- 7,000 people
- Sponsor
- Institut de Recherche pour le Developpement
COVID-19, Protection Against COVID-19 and Infections With SARS-CoV- 2
Safety and Immunogenicity of COVID-eVax, a Candidate Plasmid DNA Vaccine for COVID-19, in Healthy Adult Volunteers
This is a multicentre, open-label Phase 1/2 study, with a first-in-human (FIH) dose escalation part (Phase 1 study) followed by an open-label single arm (or two-arms, randomized) dose expansion part (Phase 2 study).
- Conditions
- COVID-19, Protection Against COVID-19 and Infections With SARS-CoV- 2, COVID-19 Immunisation
- Trial name
- NCT04788459
- Testing
- COVID-eVax, Cliniporator® and EPSGun
- Where
- 4 sites in Italy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Takis
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV 2 Infection), Hospitalized Patients
Antibodies Responses to COVID-19 Infection in Hospitalized Patients
1.5. Why this clinical study? The prevalence of seropositivity following SARS-CoV 2 infection might have its own potential benefits in terms of predicting the end of pandemic and the validity of herd immunity.
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV 2 Infection), Hospitalized Patients, Laboratory-confirmed SARS-CoV 2 Infection
- Trial name
- No-SARS (NCT04520880)
- Testing
- Testing procedure for Binding antibodies, Neutralizing antibodies
- Where
- Saudi Arabia
- Volunteers
- 158 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
COVID-19
Seroprevalence of Covid-19 in the Staff of the University Hospitals of Strasbourg
The Grand Est region is one of the most affected regions in France during the first wave of the COVID-19 epidemic. A significant increase in the number of patients hospitalized for SARS-CoV 2 infection at the University Hospitals…
- Trial name
- SeroPrevHUS (NCT05652582)
- Where
- France
- Volunteers
- 5,694 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19
Advanced Modeling of the Evolution of the Epidemiological Outbreak of SARS-CoV-2 Pandemic
The various epidemics that health systems periodically suffers require having valid and detailed information on its evolution and predictions in the short, medium and long term in real time to allow the health system to organize…
- Trial name
- NCT06070896
- Where
- Spain
- Volunteers
- 715,206 people
- Sponsor
- Hospital Galdakao-Usansolo
ARDS, Human, Covid-19
Use of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Caused by COVID-19
This is a pilot phase, open label, non-randomized study for the treatment of ARDS in patients infected with COVID-19. Subjects will be enrolled and treated with one dose of mesenchymal stem cells and follow-up will occur 90 days…
- Trial name
- NCT04456361
- Testing
- Mesenchymal Stem Cells derived from Wharton Jelly of Umbilical cords
- Where
- Mexico
- Volunteers
- 9 people
- Sponsor
- Instituto de Medicina Regenerativa
COVID-19
COVID-19 PrEP HCW HCQ Study
Off label study to evaluate the efficacy of HCQ for pre-exposure prophylaxis (PrEP) to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
- Trial name
- NCT04354870
- Testing
- Hydroxychloroquine (HCQ)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- NYU Langone Health
COVID19
Macro-scale Estimators of Covid-19's Worldwide Cases and Deaths
In this study, investigators try to estimate Covid-19 Cases and Deaths using countrywide annual macro-scale indicators (i.e., estimators) such as non-communicable disease data from WHO (who.
- Trial name
- NCT04757870
- Testing
- frequency
- Volunteers
- 1,790 people
- Sponsor
- Dr. Servet Akar
ME/CFS, Post-COVID ME/CFS
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS
The goal of this clinical trial is to learn about the effectiveness of repeated immunoadsorption intervention in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS).
- Trial name
- NCT05710770
- Testing
- Immunoadsorption
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2
Treatment of SARS Caused by COVID-19 With Ruxolitinib
In December 2019, a new virus emerged in Wuhan, China rapidly becoming a pandemic with registered cases above 800,000 around the world. The virus is now known as SARS-CoV2 calling its disease coronavirus-19 or COVID-19.
- Trial name
- NCT04334044
- Testing
- Ruxolitinib Oral Tablet
- Where
- Mexico
- Volunteers
- 77 people
- Sponsor
- Grupo Cooperativo de Hemopatías Malignas
Moderate to Severe Acute Respiratory Distress Syndrome Associated With COVID-19
Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 Infection
The objectives of this intermediate-size expanded access protocol are to assess the safety and efficacy of remestemcel-L in participants with ARDS due to coronavirus infection 2019 (COVID-19).
- Trial name
- NCT04366830
- Testing
- Remestemcel-L
- Where
- United States
- Sponsor
- Mesoblast International Sàrl
Covid19, SARS-CoV Infection
Proxalutamide Treatment for COVID-19 Female Outpatients
This study is intended to explore the possible protective role of anti-androgens in SARS-CoV-2 infection
- Trial name
- NCT04853134
- Testing
- Proxalutamide, Standard of Care
- Where
- Brazil
- Sponsor
- Applied Biology, Inc.
COVID-19 Pandemic, Immunogenicity
Safety and Immunogenicity of Omicron Variant-Matched Vaccine Booster in Adults
Under protocol versions 1.01-1.06: The five recently emerged SARS-CoV2 variants that were designated as VOCs are the Alpha variant, Beta variant, Gamma variant, Delta variant and the Omicron variant.
- Conditions
- COVID-19 Pandemic, Immunogenicity, SARS CoV 2 Infection, COVID-19
- Trial name
- SH-MO-214 (NCT05383560)
- Testing
- mRNA-1273.214 Vaccine, MRNA-1273 Vaccine, MRNA-1273.222 Vaccine
- Where
- Israel
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Heart Rhythm Disorder, Covid19
Effect of Social Isolation on Physical Activity Level, and Kinesophobia in Heart Rhythm Disorders During Pandemic
The aim of our study is to examine the effect of social isolation on physical activity level, health literacy and kinesophobia in heart rhythm disorders.
- Conditions
- Heart Rhythm Disorder, Covid19, Social Isolation
- Trial name
- NCT04818697
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Covid19
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
This is a pilot study in 24 subjects where half will be randomized to 10 treatments with hyperbaric oxygen (HBO). It will primarily study pulmonary sequelae with imaging and physiological measurements (low dose chest computer…
- Trial name
- NCT04905888
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Sponsor
- Peter Lindholm
COVID-19
Compassionate Use of Hyperbaric Oxygen Therapy
This is an observational patient registry of COVID-19 patients treated with HBOT.
- Trial name
- NCT04386265
- Where
- 11 sites in United States, Poland
- Volunteers
- 100 people
- Sponsor
- SerenaGroup, Inc.
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