Clinical trials: COVID-19 Pneumonia
COVID-19
Efficacy and Safety of Convalescent Plasma in Treating COVID-19 Hospitalized Patients
This is a Phase II study. This research study is being conducted to use convalescent donor plasma in seriously ill patients who have COVID-19.
- Trial name
- NCT04354831
- Testing
- anti-SARS-CoV-2 convalescent plasma
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Medical College of Wisconsin
COVID 19
Impact of Cryopreservation Methods on Post-Thaw SARS-CoV-2 in Semen Samples
Cryopreservation of seminal fluid or spermatozoa from epididymary and testicular retrieval represents a crucial tool in managing conditions of permanent or temporary infertility, as well as in cases of secretory and excretory…
- Trial name
- SEM-COV-19 (NCT06703723)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Covid19, Prostate Specific Antigen
Changing of Prostate Specific Antigen Value in Patients With Covid-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide pandemic in over 100 years. The disease caused by this newly discovered virus was called Covid-19.
- Trial name
- NCT05009186
- Testing
- PSA value
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Saglik Bilimleri Universitesi
Long Covid19
Cognitive Rehabilitation for People With Cognitive Covid19
Cognitive impairment is increasingly recognised as a major component of long Covid, and is estimated to be present in 25-75% of affected individuals.
- Trial name
- NCT05731570
- Testing
- Cognitive rehabilitation
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- University College, London
COVID-19, 2019 Novel Coronavirus Infection
Evaluating Clinical Parameters of COVID-19 in Pregnancy
Coronavirus infection, also known as COVID-19, has become a global pandemic with over 3 million cases and 250,000 deaths worldwide.
- Conditions
- COVID-19, 2019 Novel Coronavirus Infection, COVID-19 Infection
- Trial name
- COpregVID (NCT04470583)
- Where
- 2 sites in United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
COVID-19
A Study to Evaluate the Ability of UB-612 COVID-19 Vaccine to Boost Immunity of Heterologous COVID-19 Vaccines.
This is a study to evaluate the ability of UB-612 vaccine to boost immunity of subjects who previously received two doses of AstraZeneca COVID-19 vaccine (ChAdOx1-S) with an 8-16 week interval between first and second doses.
- Trial name
- NCT05167253
- Testing
- UB-612
- Volunteers
- healthy volunteers welcome
- Sponsor
- United Biomedical Inc., Asia
Covid19, Viral Infection
Assessment of the Clinical Effectiveness of a Herbal Extract (Cretan IAMA) in Patients With Viral Respiratory Infections, Including COVID-19, in Primary Healthcare Settings, and Co-assessment of Its Prophylactic Effect in People Cohabiting With These Patients
This single-arm, open-label small interventional proof-of-concept (POC) study study aims: 1. to assess the clinical outcomes of patients exhibiting viral respiratory infection (VRI) symptoms and seeking primary healthcare (PHC)…
- Conditions
- Covid19, Viral Infection, Respiratory Viral Infection
- Trial name
- COVID-19-IAMA (NCT04705753)
- Testing
- Cretan IAMA
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- University of Crete
Covid19, SARS-CoV Infection
Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection
SARS-CoV-2 infection seems to induce in most critical cases an excessive and aberrant hyper-inflammatory host immune response that is associated with a so-called "cytokine storm", moreover pro-thrombotic derangements of…
- Conditions
- Covid19, SARS-CoV Infection, Pneumonia, Viral, Coagulopathy
- Trial name
- STAUNCH-19 (NCT04528888)
- Testing
- Enoxaparin, Methylprednisolone, unfractionated heparin
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Massimo Girardis
COVID-19; Immunity
Investigating Immune Escape by SARS-CoV-2 Variants
The purpose of this protocol is to investigate the ability of pre-existing immunity by natural infection or vaccination to prevent infections by emerging SARS-CoV-2 variants.
- Trial name
- NCT05171803
- Testing
- No intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of California, Los Angeles
Cancer, Chemotherapy
The Effect of Music on Pain and Anxiety in Patients Receiving Chemotherapy During COVID-19
Introduction: This study has been conducted to determine the effect of music on pain and anxiety levels in patients receiving chemotherapy during COVID-19.
- Trial name
- NCT05334641
- Testing
- Listening Music, Not Listening Music
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Inonu University
COVID-19, Surgery
Impact of COVID-19 Pandemic on Hepatopancreatobiliary Surgical Services in Singapore
This paper is intended to report our observational study in evaluating the impact of the COVID-19 pandemic on Tan Tock Seng Hospital hepatopancreatobiliary unit's surgical workload from January to June across 2019 to 2022…
- Trial name
- NCT05572866
- Testing
- COVID-19 pandemic
- Where
- Singapore
- Volunteers
- 1,089 people
- Sponsor
- Tan Tock Seng Hospital
Oxygen Deficiency, Coronavirus Infection
Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure
The purpose of this study is to retrospectively review clinical data to determine whether awake proning improves oxygenation in spontaneously breathing patients with COVID-19 severe hypoxemic respiratory failure.
- Trial name
- NCT04408222
- Testing
- Awake proning
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Covid19, Cardiac Complication
One-year Cardiac Follow-up of Patients With COVID-19 Pneumonia
The primary objective of the study is to assess the cardiac status of COVID-19 pneumonia patients during 1 year after discharge
- Trial name
- NCT04501822
- Testing
- Evaluation of clinical, instrumental and laboratory diagnostics tests
- Where
- Russia
- Volunteers
- 380 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
COVID-19, SARS-CoV-2 Acute Respiratory Disease
Immunogenicity and Safety of a Booster Vaccination With a Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Healthy Adults Volunteers Fully Vaccinated Followed by an Extension Period to Study a Fourth Dose Administration.
This Phase IIb clinical study aims to compare the immunogenicity and safety of a booster dose of recombinant protein RBD fusion dimer vaccine as a heterologous booster (to subjects who have received the second dose of the…
- Trial name
- NCT05142553
- Testing
- COVID-19 Vaccine HIPRA, Cominarty (Pfizer-BioNtech)
- Where
- 10 sites in Spain
- Volunteers
- 887 people, healthy volunteers welcome
- Sponsor
- Hipra Scientific, S.L.U
COVID-19, Influenza
A Study to Evaluate the Safety and Immunogenicity of COVID-19 and Influenza Combination Vaccine
This is a randomized, observer-blinded, Phase 2 study evaluating the safety and immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARSCoV2) recombinant spike (rS) (SARS-CoV-2 rS) nanoparticle and quadrivalent…
- Trial name
- COVID-19 (NCT05519839)
- Testing
- qNIV Vaccine with Matrix-M Adjuvant, Influenza Vaccine, CIC Vaccine with Matrix-M Adjuvant
- Where
- 35 sites in Australia, New Zealand
- Volunteers
- 1,579 people, healthy volunteers welcome
- Sponsor
- Novavax
SARS-CoV2 Infection
Efficacy, Safety and Immunogenicity Study of SARS-CoV-2 Inactivated Vaccine
This phase III trial aims to assess the efficacy, safety and immunogenicity of SARS-CoV-2 Vaccine (inactivated) and lot-to-lot consistency evaluation
- Trial name
- COVID-19 (NCT04508075)
- Testing
- SARS-CoV-2 vaccine (inactivated)
- Where
- Indonesia
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
COVID-19
Dynamic Evaluation of COVID-19 Diagnostic Tests
Rapid antigenic tests are not yet used in real life. Their contribution in the diagnostic strategy based on the gold standard including anamnesis, thoracic CT and PCR has not been evaluated.
- Trial name
- TRODVID-19 (NCT04337996)
- Testing
- COVID-19 diagnostic test
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Tourcoing Hospital
Covid-19
CPI-006 Plus Standard of Care Versus Placebo Plus Standard of Care in Mild to Moderately Symptomatic Hospitalized Covid-19 Patients
This is a phase 3, randomized, placebo controlled, double-blind, multicenter, stratified study of CPI-006 plus standard of care (SOC) versus placebo plus SOC in mild to moderately symptomatic hospitalized Covid-19 patients with…
- Trial name
- NCT04734873
- Testing
- CPI-006 2 mg/kg + SOC, CPI-006 1 mg/kg + SOC
- Where
- 91 sites in United States, Argentina and 10 more
- Volunteers
- 46 people
- Sponsor
- Corvus Pharmaceuticals, Inc.
Covid19, COVID-19 Pneumonia
Efficacy and Safety of Antimicrobial Stewardship Intervention in Hospitalized COVID-19 Patients (COVASP)
COVID-19 is respiratory disease caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2), a novel coronavirus which has spread rapidly across the world with over 149.9 million laboratory confirmed cases and over 3.1…
- Conditions
- Covid19, COVID-19 Pneumonia, COVID-19 Lower Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- COVASP (NCT04896866)
- Testing
- Antimicrobial stewardship prospective audit and feedback
- Where
- 3 sites in Canada
- Volunteers
- 833 people
- Sponsor
- University of Alberta
Pneumonia, Viral, Critically Ill
French Multicentre Observational Study on SARS-Cov-2 Infections (COVID-19) ICU Management Study
Since December 2019, a new agent, the SARS-Cov-2 coronavirus has been rapidly spreading from China to other countries causing an international outbreak of respiratory illnesses named COVID-19.
- Conditions
- Pneumonia, Viral, Critically Ill, Corona Virus Infection
- Trial name
- FRENCH CORONA (NCT04340466)
- Testing
- No intervention
- Where
- France
- Volunteers
- 1,003 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
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