Clinical trials: COVID19 Patients
to Predict an Unfavorable Evolution of Covid-19 at the Hospital Admission of Patients
Prediction of Unfavourable Outcome in Newly Covid-19 Hospitalized Patient
The project is a part of the "Protocol for a multicentre study of nosocomial SARS-CoV2 transmission: The NOSO-COR Project" registered in ClinicalTrials (NCT04290780).
- Trial name
- PredictCovid19 (NCT04412031)
- Testing
- non applicable
- Where
- France
- Volunteers
- 802 people
- Sponsor
- Hospices Civils de Lyon
Pulmonary Infection, Covid-19
Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection
This study is a phase II, parallel, prospective, randomized, double-blind, placebo controlled trial. The present study will aim to address the efficacy and safety of acute administration of triiodothyronine on ICU patients…
- Trial name
- Thy-Support (NCT04348513)
- Testing
- T3 solution for injection
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
Corona Virus Disease
Anti-il6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure
Coronavirus disease 2019 (COVID-19) is caused by the newly discovered coronavirus, SARS-CoV-2. The median time from onset of symptoms of COVID-19 to development of acute respiratory distress syndrome (ARDS) has been reported as…
- Trial name
- TOCIVID (NCT04322773)
- Testing
- RoActemra iv, RoActemra sc, Kevzara sc
- Where
- 2 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Marius Henriksen
Covid19
Determination of the Hemoadsorption Impact as Adjunctive Treatment Upon the Support Therapy of COVID-19
A) Comparing the % of change in each clearances of pro-, and anti-inflammatory mediators (cytokine, chemokines and complement) in the COVID-19 patients treated with CytoSorb as compared to the same patient population who do not…
- Trial name
- NCT04518969
- Testing
- CytoSorb
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Dr David DE BELS
Oxygen Deficiency, Coronavirus Infection
Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure
The purpose of this study is to retrospectively review clinical data to determine whether awake proning improves oxygenation in spontaneously breathing patients with COVID-19 severe hypoxemic respiratory failure.
- Trial name
- NCT04408222
- Testing
- Awake proning
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Secondary Sclerosing Cholangitis, COVID-19
SSC-COVID in Patients After COVID-19
Analysis of occurrence of SSC-COVID in SARS-CoV-2-patients after the first wave of COVID-pandemic
- Trial name
- NCT05233553
- Testing
- control of liver enzymes
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University Hospital Tuebingen
COVID-19 Pneumonia, Type2diabetes
Characteristics of Blood Glucose Variability in Patients With Type 2 Diabetes Mellitus and COVID-19
using intermittently scanned continuous glucose monitoring (isCGM) to clarify the characteristics of blood glucose variability parameters in T2DM patients with NCP, guide the formulation of reasonable clinical treatment measures…
- Trial name
- NCT06156137
- Testing
- Glucose variability
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qilu Hospital of Shandong University
Cognitive Impairment, Long COVID
Addressing Cognitive Fog in Long-COVID-19 Patients
This study will assess two options to help patients better manage the cognitive fog and emotional distress that may be associated with having Long-COVID.
- Trial name
- NCT05597722
- Testing
- Digital cognitive behavioral intervention-RxWell, Amphetamine-Dextroamphetamine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Eva Szigethy
Haemoglobinopathies
Observational Study for Patients With Hemoglobinopathies and Rare Inherited Anemia and Covid 19
The COVID-19 pandemic is causing many deaths around the world, putting a strain on health services. Patients with pre-existing chronic conditions are most affected by the SARS-COV2 infection.
- Trial name
- NCT04746066
- Where
- 2 sites in Italy
- Volunteers
- 10,000 people
- Sponsor
- Società Italiana Talassemie ed Emoglobinopatie
COVID-19
Efficacy Assessment of Methylprednisolone and Heparin in Patients With COVID-19 Pneumonia
The COVID-19 pandemic has been spreading continuously, and in Brazil, until July 19, 2020, there have been more than 2,000,000 cases with more than 79,000 deaths, with daily increases.
- Trial name
- NCT04485429
- Testing
- Methylprednisolone, Heparin
- Where
- Brazil
- Sponsor
- D'Or Institute for Research and Education
Frailty, Oncology
Approaches and Metrics in Fraily Patients During COVID-19 Era
The COVID-19 pandemic started in December 2019 in Wuhan, the Chinese province of Hubei. Compared to the period of the first epidemic wave (March to May 2020), in the period of the second epidemic wave (October 2020 to July 2021)…
- Conditions
- Frailty, Oncology, Immune Deficiency
- Trial name
- COMETA (NCT05792891)
- Testing
- Collecting biological material from frail patients, with or without COVID-19
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Covid19, Vitamin D
Efficacy of Vitamin D Supplementation to Prevent the Risk of Acquiring COVID-19 in Healthcare Workers
In a blinded randomized clinical trial, which will include health workers (doctors, residents, nurses, stretcher-bearers, technicians, hygiene and cleaning) who are members of the health teams that care for patients with…
- Trial name
- COVID-19 (NCT04535791)
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Telemedicine
Covid-19 Predictors: Safety of Gynecological Oncology Patients Undergoing Systemic Cancer Therapy
We designed a monocenter prospective cohort study using PROM via app and remote monitoring via pho-toplethysmography (PPG). The application of these technologies enables an early detection of infections and therefore initiation…
- Trial name
- CO-SI-ONKO (NCT05043220)
- Testing
- PPG and PROM
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Severe COVID-19 Pneumonia
ANTIcoagulation in Severe COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may predispose patients to thrombotic disease due to a state of profound inflammation…
- Trial name
- ANTICOVID (NCT04808882)
- Testing
- Tinzaparin, Low dose prophylactic anticoagulation, Tinzaparin, High dose prophylactic anticoagulation, Tinzaparin,Therapeutic anticoagulation
- Where
- France
- Volunteers
- 353 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Allogenic Hematopoietic Cell Transplant, CAR-T Therapy
COVID-19 Vaccine in Patients After Allogeneic HCT, CAR-T Therapy and With Primary Immune Deficiency
The corona pandemic is a continuing global challenge due to Corona Virus 2019 (COVID-19). The purpose of the study is to confirm the accepted hypothesis from the recommendations of The European Society for Blood and Marrow…
- Conditions
- Allogenic Hematopoietic Cell Transplant, CAR-T Therapy, Primary Immunodeficiency
- Trial name
- NCT04724642
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Critical Illness, COVID-19
Modafinil for Wakefulness in the Critical Care Units
It has been well documented that patients in the intensive care unit (ICU) are susceptible to developing neurocognitive and musculoskeletal complications because of various factors, including the nature of the critical illness…
- Conditions
- Critical Illness, COVID-19, Cognitive Dysfunction
- Trial name
- NCT04751227
- Testing
- Modafinil
- Where
- Saudi Arabia
- Volunteers
- 8 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Covid19
Efficacy and Safety of Ovotransferrin in COVID-19 Patients
Chicken egg consists of three main components, egg white (56%), yolk (33%) and shell (11%). The key component of egg white is 88 percent water and 12 percent solids, of which over 90 percent are protein.
- Trial name
- NCT04643054
- Testing
- Ovotransferrin
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Covid19, Old Age; Debility
Mortality Due to COVID-19 in the COVID-AGEBRU Study
The COVID-Age Brugmann study aims to identify the clinical predictors of mortality risk in older patients admitted to an acute care unit due to COVID-19
- Conditions
- Covid19, Old Age; Debility, Morbidity, Multiple
- Trial name
- COVID-AGEBRU (NCT04756479)
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Brugmann University Hospital
COVID-19
Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19
This is an open label, randomized, controlled, pilot clinical study in patients with COVID-19, to obtain preliminary biologic, physiologic, and clinical data in patients with COVID-19 treated with rhACE2 or control patients, to…
- Trial name
- NCT04287686
- Testing
- Recombinant human angiotensin-converting enzyme 2 (rhACE2)
- Where
- China
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
COVID-19 Infection
Immunosupressive Treatment in COVID-19 Patients
SAM-COVID is a retrospective cohort study that aims to determine the impact of immunosuppressive drugs and immunoglubulins in the outcome of patients with COVID-19.
- Trial name
- SAM-COVID (NCT04382781)
- Testing
- NO-Immunosuppressive, Immunosuppressive, Immunoglubulins
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Spanish Network for Research in Infectious Diseases
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