Clinical trials: COVID19 Patients
COVID-19, Coronavirus
Respiratory Decompensation and Model for the Triage of COVID-19 Patients
The purpose of this study is to prospectively evaluate a machine learning algorithm for the prediction of outcomes in COVID-19 patients.
- Conditions
- COVID-19, Coronavirus, Mortality, Mechanical Ventilation
- Trial name
- READY (NCT04390516)
- Testing
- COViage
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- Dascena
Down Syndrome, SARS-CoV-2 Vaccination
Prospective Monitoring of Antibody Response Following COVID-19 Vaccination in Patients With Down Syndrome.
The risk of severe course of SARS-CoV-2 infection in people with Down Syndrome is substantially increased. The risk of death is 3-10 fold higher than in healthy people.
- Trial name
- PRIDE (NCT05145348)
- Testing
- Immune response to Sars-CoV-2 vaccinations; including COVID-19 vaccin Moderna, Comirnaty (Pfizer) and Vaxzevria (AstraZeneca)
- Where
- Netherlands
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Infection by SARS-COV-2
RDW, Platelet Kinetics and Survival Outcome in Covid-19 Hospitalized Patients.
This is a retrospective, non-interventional nor experimental study conducted at the General Hospital of Athens "Sismanoglio - A. Fleming / A.
- Trial name
- HEMLABFORCOV19 (NCT06755658)
- Where
- Greece
- Volunteers
- 500 people
- Sponsor
- Sismanoglio General Hospital
Covid19
TREATMENT WITH ANTI-SARS-COV-2 IMMUNOGLOBULIN IN PATIENTS WITH COVID-19
A Phase I/II clinical trial for safety and efficacy evaluation of treatment with anti-SARS-CoV-2 equine immunoglobulin (F(ab')2) in hospitalized patients with COVID-19 not requiring of invasive ventilation support.
- Trial name
- NCT04573855
- Testing
- Anti-SARS-CoV-2 immunoglobulin
- Volunteers
- 41 people
- Sponsor
- D'Or Institute for Research and Education
Hematopoietic and Lymphatic System Neoplasm
Self-Amplifying mRNA COVID-19 Vaccine (LUNAR-COV19) Versus Comirnaty Vaccine in Adult Hematopoietic Cell Transplant Patients
This phase IIb trial compares the effect of LUNAR-COV19 vaccine to Comirnaty vaccine in treating adult patients who have received a hematopoietic cell transplant (HCT).
- Trial name
- NCT07390968
- Testing
- SARS-CoV-2 mRNA Vaccine ARCT-021, Tozinameran, Biospecimen Collection
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Fred Hutchinson Cancer Center
Diabetic Complication, Covid19 Virus Infection
Suspicion of Hypoglycemic Effect of mRNA Based Covid-19 Vaccines (Polyethylene Glycol) Will Happen , Observational Study on Diabetic Patients at Saudia Arabia
vaccines for covid-19 are gold strategy and great achievement at this century for protection against complications of covid-19 , development of many vaccines with different technology represent a big challenge for this disease so…
- Conditions
- Diabetic Complication, Covid19 Virus Infection, Hypoglycemia, Polyethylene Glycol Adverse Reaction
- Trial name
- NCT05087225
- Testing
- polyethelyene glycol
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
COVID-19
Clinical Decision Support System Based on Non-invasive Tele-monitoring of COVID-19 Patients
The aim of the study is to provide clinical decision support to healthcare professionals using a wearable for non-invasive multimodal monitoring, allowing early detection of disease progression to severe forms, as well as the…
- Trial name
- SOY+ (NCT04802018)
- Testing
- Clinical decision support system based on non-invasive multimodal monitoring
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Increase-Tech
Covid19
Evaluation of the Efficacy of High Doses of Methylprednisolone in SARS-CoV2 ( COVID-19) Pneumonia Patients
This double blind, randomized study is aiming to evaluate the efficacy of three doses (1gr/day) of methylpredisolone added to standard therapy in patients, with documented COVID-19 pneumonia, requiring hospitalization but not…
- Trial name
- NCT04673162
- Where
- 20 sites in Italy
- Volunteers
- 260 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Dialysis, Covid19
Antibody Response in Hemodialysis and Non-dialysis Patients Diagnosed With COVID-19.
This is prospective cohort study aimed to compare antibody response against SARS-CoV-2 in dialysis patients and non-dialysis-dependent volunteers.
- Trial name
- COV-HD (NCT04633915)
- Where
- Russia
- Volunteers
- 51 people
- Sponsor
- Saint Petersburg State University, Russia
COVID 19
Cognitive and Psychological Disorders After Severe COVID-19 Infection
As COVID-19 pandemic is still ongoing, patients follow-up begins to reveal cognitive and psychological disorders. There are not yet well described, neither their physiopathology.
- Trial name
- NEUROCOG-COVID (NCT04937582)
- Testing
- Cognitive assessment, Imaging, Routine care
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Central Hospital, Nancy, France
Covid19, Eye Diseases
Impact of COVID-19 on Quality of Life of Seniors With Eye Disease and Implementations to Improve Wellness
The ophthalmology clientele is vulnerable in the context of the coronavirus disease 2019 (COVID-19) pandemic because of their age and comorbidities.
- Trial name
- NCT04910282
- Where
- Canada
- Volunteers
- 425 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Covid19
Understanding Immunology and Patient Outcomes of COVID-19 in Hospitalized Patients
The adaptive immune response, consisting of antiviral T and B cells, is critical for providing protection against viruses such as SARS-CoV-2, both during an active infection and later following a subsequent exposure.
- Trial name
- NCT04892797
- Testing
- Covid-19+ observational
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Vermont
Liver Cirrhosis
Safety and Efficacy of a Non-replicating ChAdOx1 Vector Vaccine AZD1222 (COVISHIELD), for Prevention of COVID-19 in Patients With Liver Cirrhosis
COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had caused widespread impact on health, including substantial mortality among those with pre-existing health conditions including…
- Trial name
- NCT04794946
- Testing
- Covishield
- Where
- India
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
COVID-19
A Real World Study of Paxlovid for the Treatment of Hospitalized Patients Confirmed With COVID-19
The study was designed to analyze the efficacy and safety of Paxlovid for the treatment of COVID-19.
- Trial name
- NCT05387369
- Testing
- Paxlovid
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Huashan Hospital
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
COVID, Sars-CoV2
Echocardiography in Critically-ill Patients With COVID-19 Pneumonia
Critical care echocardiography (CCE) has been widely used since the 10 last years. Covid outbreak leads that many patients with acute respiratory failure were admitted in the ICU.
- Trial name
- ECHO-COVID (NCT04414410)
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Hospital Ambroise Paré Paris
Covid19, Diabetes Mellitus
The Effect of Diabetes Mellitus on Mortality of Patients With COVID-19
The study includes patients over 18 years old who were hospitalized in our covid intensive care unit between March 16 and May 16, 2020. Retrospective records were examined by examining the electronic data files of the patients.
- Trial name
- NCT04663659
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
SARS-CoV-2 Infection
A Study to Assess the Efficacy and Safety of XC221 in Patients With COVID-19
The innovative drug XC221 100 mg tablet is designed for the treatment of COVID-19 (SARS-CoV-2 infection). A multicenter, adaptive, randomized, double-blind, placebo-controlled Phase III clinical study is aimed to assess the…
- Trial name
- NCT04487574
- Testing
- XC221
- Where
- 5 sites in Russia
- Volunteers
- 118 people
- Sponsor
- RSV Therapeutics LLC
Covid19, Exercise
Inspiratory Muscle Training in COVID-19 Patients
This study aims to investigate whether adjunctive inspiratory muscle training (IMT) can enhance the benefits of pulmonary rehabilitation (PR) in patients with COVID-19.
- Trial name
- ADDIMTCOVID (NCT04595097)
- Testing
- inspiratory muscle traiing
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- Escola Superior de Ciencias da Saude
COVID19
Expanded Access to Convalescent Plasma for the Treatment of Patients With COVID-19
This expanded access program will provide access to investigational convalescent plasma for patients in acute care facilities infected with SARS-CoV-2 who have severe or life-threatening COVID-19, or who are judged by a…
- Trial name
- NCT04338360
- Testing
- COVID-19 convalescent plasma
- Where
- 12 sites in United States
- Sponsor
- Mayo Clinic
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