Clinical trials: COVID19 Patients
COVID, Acute Respiratory Distress Syndrome
Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress Syndrome
Corona virus disease 2019 (COVID-19) has been declared as a Pandemic by the World Health Organization (WHO). According to WHO report on March 31st 2020, globally COVID-19 have infected over 750,000 people and caused over 36,000…
- Trial name
- NCT04380935
- Testing
- Convalescent plasma, Standard of care
- Where
- 3 sites in Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Covid19
COVID-19 3rd Dose Vaccine in Transplant Patients
The purpose of this study is to investigate the efficient vaccine type as a booster dose for Coronavirus Disease of 2019 (COVID-19) in solid organ transplant recipients.
- Trial name
- NCT05047640
- Testing
- BNT162b2 vaccine, JNJ-78436735 Vaccine
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Giselle Guerra
Post-intensive Care Syndrome, COVID-19
Clinical and Functional Characteristics of Patients Admitted for Severe COVID-19 Pneumonia
This research protocol aims to evaluate the impact of severe COVID-19 pneumonia requiring invasive mechanical ventilation (IMV) on health-related quality of life (HRQoL), functional capacity, muscle strength, and nutritional…
- Trial name
- EQOL-COVID (NCT06727474)
- Testing
- Health-Related Quality of Life (HRQoL) with EQ-5D-3L
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
COVID-19 Infection
Extension Study in a Cohort of Adult Patients With COVID-19 Infection
The main objective of this study is to evaluate the incidence of post-COVID morbidity and characterize the complications profile in patients who participated in the APLICOV-PC study.
- Trial name
- E-APLICOV-PC (NCT05121740)
- Testing
- Plitidepsin 1.5 mg / day, Plitidepsin 2.0 mg / day, Plitidepsin 2.5 mg / day
- Where
- 10 sites in Spain
- Volunteers
- 34 people
- Sponsor
- PharmaMar
COVID-19, Pneumonia, Viral
Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection
In light of the ongoing COVID-19 epidemic in Norway, it is paramount to develop and utilize clinical tools for assessing and risk stratifying patients with suspected coronary infection in the emergency departments.
- Conditions
- COVID-19, Pneumonia, Viral, Pulmonary Infection
- Trial name
- COVIDUS-NOR (NCT04422691)
- Testing
- Lung ultrasound
- Where
- 9 sites in Norway
- Volunteers
- 5 people
- Sponsor
- St. Olavs Hospital
Covid19
A Phase 2 Clinical Trial of MW33 Injection in Patients With COVID-19
This study is designed as a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the clinical efficacy and safety of MW33 injection in patients with mild or moderate COVID-19, and to evaluate its…
- Trial name
- NCT04627584
- Testing
- MW33 injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
COVID-19, Lymphocytopenia
InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection ( ILIAD-7-US-I )
Comparison of the effects of CYT107 vs Placebo administered IM at 10μg/kg twice a week for three weeks on immune reconstitution of lymphopenic COVID-19 patients
- Trial name
- ILIAD-7-US-I (NCT04442178)
- Testing
- CYT107
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Revimmune
Mesenchymal Stem Cell, COVID-19 Pneumonia
UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients With Refractory Hypoxia
The goal of this randomized, controlled, open-labeled interventional clinical trial is to test the efficacy and safety of umbilical cord mesenchymal stem cells (UC- MSCs) in the treatment of severe and critical COVID-19 patients…
- Trial name
- NCT05689008
- Testing
- UC-MSCs treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai East Hospital
Covid19, Kidney Diseases
RECOVAC Repeated Vaccination Study
Rationale: The humoral and cellular immune response after two mRNA vaccinations is severely attenuated in kidney transplant patients compared to controls, especially when their immunosuppressive regimen contains mycophenolate…
- Conditions
- Covid19, Kidney Diseases, Vaccine Response Impaired, SARS-CoV2 Infection
- Trial name
- NCT05030974
- Testing
- mRNA-1273, Ad26.COV2.S vaccine
- Where
- 4 sites in Netherlands
- Volunteers
- 336 people
- Sponsor
- University Medical Center Groningen
Respiratory Infection Virus, Respiratory Failure
Sivelestat for Acute Respiratory Distress Syndrome Due to COVID-19
A randomized, double-Blind, placebo-controlled trial aimed to investigate the safety and efficacy of sivelestat on treating adult patients with COVID-19-related acute respiratory distress syndrome (ARDS)
- Trial name
- NCT05697016
- Testing
- Sivelestat Sodium for Injection
- Volunteers
- 238 people
- Sponsor
- Beijing Tiantan Hospital
Autoimmune Liver Disease, COVID-19
Study of Clinical Features of Patients With Autoimmune Liver Disease Complicated With Covid-19 and the Immune Mechanism Affecting Prognosis
With the decreasing virulence of omicrons strain, the current domestic epidemic prevention policy has been changed based on the health of the people and the development needs of the country.
- Trial name
- NCT06099626
- Testing
- Different types of disease
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
COVID-19, Cytokine Storm
Intercellular Adhesion Molecule-1 and TNF-α in Patients With COVID-19
This study aimed to assess the cytokine profile in COVID 19 patients and its relation with disease progression \& severity using COVID reporting and data system (CORADS) score.
- Trial name
- NCT05408325
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
COVID 19
Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia
Coronavirus-2019 disease (COVID-19) and community-acquired pneumonia are significant problems of modern medicine. Pneumonia is the most common severe complication of COVID-19.
- Trial name
- TARGET-VIP (NCT04522076)
- Where
- 2 sites in Russia
- Volunteers
- 1,130 people
- Sponsor
- National Research Center for Preventive Medicine
Covid19, Cancer
Prospective Determination of COVID-19 Infection Rate in a Chemotherapy Unit in Mexico.
Cancer patients are considered vulnerable to COVID-19 infection. During the pandemic, cancer patients may need to continue their regular treatment of chemotherapy and / or radiotherapy and therefore must visit a hospital unit.
- Conditions
- Covid19, Cancer, Tumor
- Trial name
- NCT04567979
- Where
- Mexico
- Volunteers
- 149 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Covid19, SARS-CoV-2 Infection
A Trial of GC4419 in Patients With Critical Illness Due to COVID-19
A Trial of GC4419 in Patients with Critical Illness due to COVID-19
- Trial name
- NCT04555096
- Testing
- GC4419
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Galera Therapeutics, Inc.
Pneumonia Due to COVID-19
Education Impact on Rehabilitation of Hospitalized Patients With Pneumonia and COVID-19
The planned research will enable the assessment of rehabilitation's effects using two pulmonary rehabilitation models: conventional and supplemented with an education program for patients hospitalized due to pneumonia with…
- Trial name
- NCT06522724
- Testing
- Education program, Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Rzeszow
Physical Activity, COVID-19
Physical Activity Following the Containment Period Imposed by the COVID-19 Pandemic in Patients
In the context of the containment imposed by the COVID-19 pandemic and taking into account the numerous restrictions imposed, the practice of physical and sports activities (PSA) could be reduced by general population and sports…
- Trial name
- PhysiCOVID (NCT04451317)
- Testing
- Questionnaire, phone call
- Where
- 2 sites in France
- Volunteers
- 499 people
- Sponsor
- University Hospital, Toulouse
SARS-CoV2 Infection
Efficacy and Safety of EXOSOME-MSC Therapy to Reduce Hyper-inflammation In Moderate COVID-19 Patients
In COVID-19 infection caused by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a dysregulation of the immune system response that causes cytokine storm syndrome.
- Trial name
- EXOMSC-COV19 (NCT05216562)
- Testing
- Exosome-MSC Intravenous injection, COVID-19 Standard Treatment
- Where
- 3 sites in Indonesia
- Volunteers
- 60 people
- Sponsor
- Dermama Bioteknologi Laboratorium
COVID, Hypoxic Respiratory Failure
Incline Positioning in COVID-19 Patients for Improvement in Oxygen Saturation
COVID-19 is a respiratory illness caused by SARS-CoV-2 with a range of symptoms from mild, self-limiting respiratory tract infections to severe progressive pneumonia, multiorgan dysfunction and death.
- Trial name
- UPSAT (NCT04344561)
- Testing
- Postural Positioning
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Johns Hopkins University
Trauma, Covid19
The Impact of COVID-19 Pandemic to Trauma Patients in Emergency Department: A Multicenter Experience of Istanbul
COVID-19, which emerged in China in December 2019, has become a pandemic with its spread to many countries of the world. The aim of this multi-centered study is to guide for the approach, organization, diagnosis and treatment of…
- Trial name
- NCT04479124
- Testing
- COVID-19 PCR
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
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