Clinical trials: COVID19 Patients
COVID-19
Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected)
Phase III, single-center with co-participating units, randomized, double-blind, parallel, placebo-controlled clinical study
- Trial name
- NCT05033145
- Testing
- AZVUDINE
- Where
- 7 sites in Brazil
- Volunteers
- 312 people
- Sponsor
- HRH Pharmaceuticals Limited
Covid19
Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in the Context of Suspicion of COVID-19 Infection
In the context of the actual pandemia of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which requires a better diagnostic strategy for the management of patients.
- Trial name
- VOC-COVID-Diag (NCT04614883)
- Testing
- Volatile Organic Compounds analysis, Canine odor detection of Volatile Organic Compounds
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Hopital Foch
Covid19
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis
A multicenter, adaptive, randomized platform trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge
- Trial name
- NCT04650087
- Testing
- Apixaban 2.5 MG
- Where
- 121 sites in United States
- Volunteers
- 1,291 people
- Sponsor
- Thomas L. Ortel
Feeding and Eating Disorders
Impact of COVID-19 Lockdown on Obesity and Eating Behaviors
COVID-19 lockdown presents particular challenges for people living with obesity. Indeed during this period, the lifestyle was deeply modified: diet, activity, and sleep behaviours, home office, take care of child, social…
- Trial name
- CIO (NCT04431284)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV-2 Infection, COVID-19 Recurrent
Efficacy of a Physical and Respiratory Rehabilitation Program for Patients With Persistent COVID-19 (SARS-CoV-2).
The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of a plethora of persistent, diffuse and heterogeneous symptoms such as fatigue, shortness of breath and…
- Conditions
- SARS-CoV-2 Infection, COVID-19 Recurrent, Cognitive Dysfunction, Fatigue
- Trial name
- COPERIA-REHAB (NCT05629884)
- Testing
- COPERIA-REHAB
- Where
- 4 sites in Spain
- Volunteers
- 56 people
- Sponsor
- Fundacin Biomedica Galicia Sur
COVID-19
Methodist Health System COVID-19 Patient Registry
This is a prospective cohort observational registry study that will include data on all patients who are treated at MHS facilities for COVID-19.
- Trial name
- NCT04477889
- Testing
- Treatment for COVID-19
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Methodist Health System
Thrombopenia, Covid19
COVID-19 ThromboprophylaXIs Study of Novel FXIa Inhibitor Frunexian (EP-7041) in ICU Patients
This is a multicenter, open-label, single cohort study of patients with confirmed COVID-19 syndrome who based on clinical judgment require care in an intensive care unit, regardless of whether or not mechanical ventilation is in…
- Trial name
- NCT05040776
- Testing
- EP-7041 Injection
- Where
- United States
- Sponsor
- eXIthera Pharmaceuticals
SARS-CoV 2, COVID
Precision Immunology to Determine the Immune Response in Patients With COVID-19
To better understand the immune response to SARS-CoV-2 infection, we devised a precision immunology approach to systematically study the immune function of different patient cohorts
- Trial name
- NCT04360733
- Testing
- Blood draw
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bonn
COVID-19, Post-COVID-19
Cognitive Training and Brain Stimulation in Patients With Post-COVID-19 Cognitive Impairment
The aim of the study is to investigate effects of brain stimulation-assisted cognitive training in patients with persistent subjective or objective cognitive impairment after polymerase chain reaction (PCR)-positive COVID-19…
- Trial name
- NCT04944147
- Testing
- Anodal tDCS, Intensive cognitive training, Progressive muscle relaxation (PMR)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Medicine Greifswald
Patients Undergoing Elective Surgery With Anesthesia
Telemedical Risk Assessment and Preoperative Evaluation (TAPE)
The purpose of this study is to assess the feasibility, patient satisfaction and time saving of a telemedical risk assessment and preoperative evaluation for anesthesia.
- Trial name
- NCT04518514
- Testing
- TAPE-Software
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Post-Acute COVID-19 Syndrome
Cognitive, Psychological, and Physical Functioning in Long-COVID Patients With Different Levels of Fatigue.
Post COVID-19 usually occurs 3 months from the onset of COVID-19 with symptoms that last for at least 2 months and cannot be explained by an alternative diagnosis.
- Trial name
- NCT05758558
- Where
- Belgium
- Volunteers
- 69 people
- Sponsor
- Hasselt University
Respiratory Failure, Ventilatory Failure
Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection
This study uses the AirGo band to monitor changes in tidal ventilation in spontaneously breathing patients with COVID-19 associated respiratory failure.
- Conditions
- Respiratory Failure, Ventilatory Failure, COVID-19, Pneumonia
- Trial name
- NCT04356443
- Testing
- AirGo Respiratory Monitor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
SARS-CoV-2 Acute Respiratory Disease
Muscle Evaluation of Patients Infected by the Coronavirus
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents risk to develop muscle weakness associated with prolonged period of mechanical ventilation support and hospital stay.
- Trial name
- NCT05063214
- Testing
- Muscle ultrasound evaluation
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- Hospital Israelita Albert Einstein
Covid-19 Pandemics, Tuberculosis
Immunogenicity of COVID-19 Vaccines in Tuberculosis Patients
This study is a non-randomized observation and comparison of immune response between bacteriologically confirmed TB patients under treatment cohort who received COVID-19 vaccine (n=54) vs healthy individuals (n=54).
- Trial name
- CVTB (NCT05571735)
- Testing
- Pfizer-BioNTech COVID-19 vaccine, AstraZeneca vaccine, Janssen Ad26.COV2.S COVID-19 vaccine
- Where
- Thailand
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hospitalized Patients With Covid-19 Pneumonia
Use of Ascorbic Acid in Patients With COVID 19
Different studies showed that ascorbic acid (vitaminC) positively affects the development and maturation of T-lymphocytes, in particular NK (natural Killer) cells involved in the immune response to viral agents.
- Trial name
- NCT04323514
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Nociceptive Pain
Nociception and BIS Level Monitoring in COVID-19 Patients in the Intensive Care Unit
Pain (nociception), stress and discomfort are difficult to detect in sedated and intubated patients during mechanical ventilation.
- Trial name
- NEMO (NCT05579106)
- Testing
- Nociception Level Monitor (NOL) by Medasense Biometrics Ltd., Israel, Bispectral index (BIS), Questionnaire perception of the nurse on pain patient
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Leiden University Medical Center
COVID 19 Disease
Tafenoquine in Patients With Mild to Moderate COVID-19
A clinical study to assess the efficacy and safety of oral tafenoquine compared to placebo in patients with mild to moderate COVID 19 disease.
- Trial name
- NCT04533347
- Testing
- Tafenoquine Oral Tablet
- Where
- 10 sites in United States
- Volunteers
- 86 people
- Sponsor
- 60 Degrees Pharmaceuticals LLC
Covid19, COVID-19 Respiratory Infection
Standardized Olive Leaf Capsules; as a Co-therapy in the Treatment of COVID-19 Patients
Starting from December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has caused a tremendous economic loss and unprecedented health crisis across the globe.
- Conditions
- Covid19, COVID-19 Respiratory Infection, Symptoms and Signs, COVID-19 Acute Bronchitis
- Trial name
- NCT04873349
- Testing
- Nusapure standardized olive leaves capsule, 750 mg (50% oleuropein)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Shimaa M. Abdelgawad
COVID-19, Cardiovascular Diseases
The McGill RAAS-COVID-19 Trial
Coronavirus disease (COVID-19) related pneumonia significantly impact patients with underlying cardiovascular (CV) conditions. Animal studies suggest that drugs commonly used to treated CV diseases may increase the ability of…
- Trial name
- RAAS-COVID (NCT04508985)
- Testing
- Temporarily holding the RAAS inhibitor [intervention], RAAS inhibitor [continued standard of care]
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Covid19, Corona Virus Infection
Expanded Access to Zofin for Patients With COVID-19
This expanded access protocol will provide access to the investigational product Zofin for patients in outpatient facilities infected with SARS-CoV-2 who have mild to moderate COVID-19, or who are judged by a healthcare provider…
- Conditions
- Covid19, Corona Virus Infection, SARS (Severe Acute Respiratory Syndrome), Acute Respiratory Distress Syndrome
- Trial name
- NCT04657406
- Testing
- Zofin
- Sponsor
- ZEO ScientifiX, Inc.
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