Clinical trials: COVID19 Patients
COVID 19 Disease, Mild to Moderate COVID 19 Disease
A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression
A clinical study to assess the efficacy and safety of oral tafenoquine compared to placebo in patients with mild to moderate COVID 19 disease and low risk of disease progression (the "ACLR8-LR" study).
- Conditions
- COVID 19 Disease, Mild to Moderate COVID 19 Disease, SARS-CoV-2, Infectious Disease
- Trial name
- NCT05947812
- Testing
- Tafenoquine Oral Tablet
- Volunteers
- 148 people
- Sponsor
- 60P Australia Pty Ltd
Cardiovascular Diseases, COVID
Cardiovascular Manifestations of COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the novel coronavirus disease 2019 (COVID-19). The first reports of COVID-19 came from Wuhan, China in December of 2019.
- Trial name
- NCT04335630
- Testing
- Electrocardiogram, telemetry, echocardiogram, laboratory values
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Memorial Hermann Health System
Acute Respiratory Distress Syndrome (ARDS), COVID-19
Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemia
The purpose of our prospective monocentric, randomized, controlled trial is to evaluate the effects of intravenous lidocaine on gas exchange and inflammation in acute respiratory distress syndrome (ARDS) due or not to Covid-19…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), COVID-19, Corona Virus Infection
- Trial name
- LidoCovid (NCT04609865)
- Testing
- Lidocaine 2%, Control
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Fear, Anxiety
Fear and Anxiety Level in Dental Patients During the COVID-19 Pandemic
Psychological support may be needed to help patients in the face of emotional disturbances that may be associated with the outbreak and to help them accomplish their fear and anxiety.
- Conditions
- Fear, Anxiety, COVID-19
- Trial name
- NCT05191407
- Where
- Turkey (Türkiye)
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Zeliha Aytekin
COVID-19 Pandemic, Anesthesia
Intraoperative Lung Mechanics and Functional Evaluation in Post COVID-19 Thoracotomy Patients
At the end of 2019, cases of an unknown respiratory infection were reported in the city of Wuhan in China. It was determined that the cause of this infection was a new virus belonging to the coronavirus family, which was named…
- Conditions
- COVID-19 Pandemic, Anesthesia, Thoracic Diseases
- Trial name
- NCT05851807
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
COVID-19
Efficacy and Safety Study of Nitazoxanide (NTX) in the Treatment of Patients With SARS-CoV-2 Virus Infection (COVID-19)
Evaluation of the efficacy and safety of NTX in adult patients (≥18 years and <60 years), with SARS-CoV-2 infection with mild symptoms of COVID-19, compared to a placebo control arm.
- Trial name
- NCT04463264
- Testing
- Nitazoxanide
- Where
- Argentina
- Volunteers
- 135 people
- Sponsor
- Laboratorios Roemmers S.A.I.C.F.
SARS-CoV Infection, Severe Acute Respiratory Syndrome (SARS) Pneumonia
Methylprednisolone in the Treatment of Patients With Signs of Severe Acute Respiratory Syndrome in Covid-19
This is a double-blind, randomized, placebo-controlled, phase IIb clinical trial to assess the efficacy of injectable methylprednisolone sodium succinate (MP) in patients with severe acute respiratory syndrome (SARS) in COVID-19…
- Trial name
- MetCOVID (NCT04343729)
- Testing
- Methylprednisolone Sodium Succinate
- Where
- Brazil
- Volunteers
- 416 people
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Acute Respiratory Failure With Hypoxia
ARDS Caused by COVID-19
Patients with the acute respiratory distress syndrome (ARDS) have markedly varied clinical presentations. Main characteristics of mechanically ventilated ARDS caused by COVID-19, and adherence to lung-protective ventilation…
- Trial name
- NCT04368975
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Clinic of Barcelona
Intensive Care Unit, SARS-Cov-2
COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric Non Interventional Study
Infection with the SARS-CoV-2 coronavirus (COVID-19) has recently been identified as a pandemic due to the speed and global scale of its transmission.
- Trial name
- RICO (NCT04392401)
- Testing
- Collection of blood samples in order to create a biocollection
- Where
- 8 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Patients With COVID-19 Pneumonia Will Allow to Detect an Absolute Reduction in the Rate of Respiratory-failure
Defibrotide in COVID-19 Pneumonia
Phase II, prospective, interventional, single-arm, multicentric, open label trial, with a parallel retrospective collection of data on not treated patients from IRCCS, San Raffaele Scientific Institute included in the…
- Trial name
- DEFI-VID19 (NCT04335201)
- Testing
- Defibrotide Injection
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Functional Disorder, Bodily Distress Syndrome
Central Processing of Odour Stimuli in Patients With Functional Somatic Disorder, MCS or Post Covid Compared to Healthy Controls
Background: Functional somatic disorders (FSD) are frequent in all medical settings and characterized by persistent physical symptoms that cannot be explained by other somatic or psychiatric conditions.
- Conditions
- Functional Disorder, Bodily Distress Syndrome, Multiple Chemical Sensitivity, Post COVID-19
- Trial name
- NCT04935307
- Testing
- MRI and paraclinical tests
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
SARS-CoV-2 Infection
SARS-CoV-2 in Stools Compared to Respiratory Viral Strains.
The aim of the study is to characterize and to quantify SARS-CoV-2 strains in stools, in comparison with the viral strains in respiratory samples, from patients hospitalized for COVID-19.
- Trial name
- Spread-COVID (NCT05567419)
- Testing
- Biological assays
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
COVID-19
Compassionate Use of Hyperbaric Oxygen Therapy
This is an observational patient registry of COVID-19 patients treated with HBOT.
- Trial name
- NCT04386265
- Where
- 11 sites in United States, Poland
- Volunteers
- 100 people
- Sponsor
- SerenaGroup, Inc.
Coronavirus, Fatigue
Efficacy of an Asynchronous Telerehabilitation Programme in Post-COVID-19 Patient
SARS-CoV-2 is the coronavirus responsible for developing the disease known as COVID-19. Its evolution can range from an asymptomatic course, to rapidly evolve and cause an acute respiratory syndrome.
- Conditions
- Coronavirus, Fatigue, Musculoskeletal Complication
- Trial name
- NCT04794036
- Testing
- Asynchronous telerehabilitation programme, Rehabilitation programme
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Universidad San Jorge
COVID-19
Zilucoplan® in Improving Oxygenation, Short-, Longterm Outcome of COVID19 Patients With Acute Hypoxic Respiratory Failure
The study is a randomized controlled, open-label trial comparing subcutaneous Zilucoplan® with standard of care to standard of care alone.
- Trial name
- ZILU-COV (NCT04382755)
- Testing
- Zilucoplan®
- Where
- 9 sites in Belgium
- Volunteers
- 81 people
- Sponsor
- University Hospital, Ghent
Long Covid19
Long-term Effects of SARS-CoV-2 on the Central Nervous System and One-year Follow-up of "Long COVID-19" Patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the seventh coronavirus known to infect humans, and causing coronavirus disease 2019 (COVID-19). .
- Trial name
- NCT05492292
- Testing
- Perfusion brain scintigraphy imaging
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Long COVID, Post-Acute COVID-19
Post-Covid Condition Cohort: Evolution of Symptomatology, Patient Profile and Associated Prognostic Factors
The aim of our cohort is to collect prospectively, in a standardized and exhaustive manner, the health data of patients referred to the CAPCoV, our holistic referal post covid clinics for post-covid condition in order to be able…
- Conditions
- Long COVID, Post-Acute COVID-19, Post-Acute COVID19 Syndrome
- Trial name
- SYNPOCov (NCT05610436)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Cancer, Covid19
Immunogenicity and Safety of COVID-19 Vaccine in Cancer Patients
Serum antibody titre against COVID-19 spike protein will be measured before, after the first dose, and after the second dose (when applicable) in cancer patients who are receiving or received anti-cancer drugs.
- Trial name
- NCT04910295
- Testing
- COVID-19 vaccine
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Coronavirus
Convalescent Plasma to Limit Coronavirus Associated Complications
Researchers are trying to assess the treatment potential and safety of anti-SARS-CoV-2 convalescent plasma in patients with acute respiratory symptoms with confirmed COVID-19.
- Trial name
- NCT04325672
- Testing
- Convalescent Plasma
- Sponsor
- Mayo Clinic
Nurse, in Northern New Jersey
Nurses Caring for Patients With Covid-19
The main goal of this study was to understand the perceptions of nurses who cared for patients with Covid-19 at the onset of the pandemic in Northeast USA.
- Conditions
- Nurse, in Northern New Jersey, Providing Care to Adults With Covid-19
- Trial name
- NCT06012539
- Testing
- Qualitative (interviews)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Atlantic Health System
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