Clinical trials: COVID19 Patients
Sars-CoV2, COVID-19
Implementation of Physiotherapy on COVID-19 Patients in ICU
Despite new charachersitics of COVID-19 patients, critical care implementation seems to be similar to those with Acute Respiratory Distress Syndrome (ARDS) in intensive care units (ICU).
- Trial name
- PHYSIO-COVID (NCT04347070)
- Testing
- Phsyiotherapy
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
COVID-19
Administration of Anti-SARS-CoV-2 Convalescent Plasma in Hospitalized, Non-ICU Patients With COVID-19
The purpose of this study is to assess the efficacy and safety of the administration of anti-SARS-CoV-2 convalescent plasma in COVID-19 patients who are sick enough to warrant hospitalization, but not yet admitted to the ICU…
- Trial name
- NCT04467151
- Testing
- anti-SARS-CoV-2 plasma
- Sponsor
- Kashif Khan
SARS Virus
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19
The purpose of the study is to assess the frequency of the occurrence of a venous thrombosis in patients with the new Coronavirus disease, who are admitted to the Intensive Care Unit for impending respiratory failure requiring…
- Trial name
- NCT04567927
- Testing
- Ultrasonography
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Chiesa Alessandro Felice
Covid19
Study to Investigate the Clinical Efficacy of Isoquercetin in Patients With COVID-19
The purpose of this study is to investigate the clinical efficacy of Isoquercetin in preventing disease progression and symptoms improvement in mild-to-moderate hospitalised COVID-19 patients.
- Trial name
- NCT04733651
- Testing
- Hospital standard of care for COVID-19, Isoquercetin
- Volunteers
- 250 people
- Sponsor
- Nepal Health Research Council
Corona Virus Disease 2019(COVID-19)
Treatment With Human Umbilical Cord-derived Mesenchymal Stem Cells for Severe Corona Virus Disease 2019 (COVID-19)
COVID-19 caused clusters of severe respiratory illness and was associated with 2% mortality. No specific anti-viral treatment exists.
- Trial name
- NCT04288102
- Testing
- UC-MSCs, Saline containing 1% Human serum albumin（solution without UC-MSCs）
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Beijing 302 Hospital
Covid19
Safety and Preliminary Efficacy Study of GX-I7 in Patients With COVID-19
This study is a phase 1b clinical trial to investigate the safety and preliminary effects of a single dose of a test drug or placebo to the subjects who has diagnosed as COVID-19 infection.
- Trial name
- NCT04730427
- Testing
- GX-I7, GX-I7 vehicle
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Genexine, Inc.
SARS CoV 2 Infection
Consequences in ICU of Vaccination Status of Covid-19 Patients
It is a retrospective cohort study aiming to describe the characteristics, management and prognosis of vaccinated patients hospitalized in the intensive care unit (ICU), in comparison with non-vaccinated patients.
- Trial name
- CIVIC (NCT06191341)
- Where
- France
- Volunteers
- 1,058 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Coronavirus, COVID-19 Respiratory Infection
Protocol of Assistance to Patients With Covid-19 Submitted to Treatment With HD-tDCS
COVID-19 has a variety of symptoms from asymptomatic respiratory dysfunction to death. Considering the pathophysiology of SARS-CoV-2 and its relationship with the neuroimmune system, response, autonomic balance, musculoskeletal…
- Trial name
- NCT04844554
- Testing
- Active HD-tDCS 3mA
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Hypoxemia, Covid-19
Oxygen Saturation: Analytical Comparison for COVID
In many patients, respiratory Sars-Cov2 infection causes arterial hypoxemia, which remains without signs of verbalized respiratory distress, up to a point.
- Trial name
- SHOCOVID (NCT04874805)
- Testing
- Measurement of oxygen saturation
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Anxiety
Coronavirus Anxiety in Patients Using Biologic vs Conventional DMARDs
The COVID-19 pandemic has caused significant psychological distress among patients with chronic diseases. Individuals receiving immunosuppressive therapies may experience increased anxiety due to perceived vulnerability to…
- Conditions
- COVID-19, Anxiety, Rheumatic Diseases
- Trial name
- NCT07436494
- Testing
- Current treatment (no intervention assigned)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa City Hospital
COVID
COVID-19 : Neutralizing Human Monoclonal Antibodies Against SARS-Cov-2
Rationale : The emergence of the novel, pathogenic SARS-coronavirus 2 (SARS-CoV-2) threatens public health. To date, there are no effective drug option to prevent the infection, nor therapeutics for controlling the deadly…
- Trial name
- ANTI-COV-2 (NCT04354766)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Corona Virus Infection, ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia.
The aim of the study is to compare two methods of oxygen therapy in patients with acute respiratory distress syndrome in the course of SARS-CoV2 pneumonia.
- Conditions
- Corona Virus Infection, ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2, Oxygen Deficiency
- Trial name
- NCT05197686
- Testing
- Oxygen theraphy with high flow nasal cannule, Oxygen theraphy with mask with reservoir
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Pomeranian Medical University Szczecin
Long COVID, Chronic Fatigue Syndrome
tVNS in Long COVID-19
A prior open label study has shown that transcutaneous vagus nerve stimulation [tVNS] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill…
- Trial name
- NCT06585254
- Testing
- Transcutaneous vagus nerve stimulator
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
COVID19 Pneumonia
Trial Evaluating Efficacy and Safety of Anticoagulation in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort
COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. There is currently no vaccine to prevent Covid-19 or infection with SARS-CoV-2 or therapeutic agent to…
- Trial name
- CORIMMUNO-COAG (NCT04344756)
- Testing
- Tinzaparin or unfractionated heparin
- Where
- 3 sites in France
- Volunteers
- 808 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid-19, Cytokine Storm
Treatment of Severe COVID-19 Patients Using Secretome of Hypoxia-Mesenchymal Stem Cells in Indonesia
In this randomized controlled trial (RCT), severe cases of COVID-19 infection will be treated with secretome of hypoxia-mesenchymal stem cells.
- Trial name
- NCT04753476
- Testing
- Injection of Secretome-MSCs, Standard treatment of Covid-19
- Where
- 6 sites in Indonesia
- Volunteers
- 48 people
- Sponsor
- Stem Cell and Cancer Research Indonesia
COVID-19
Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial
This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization.
- Trial name
- CATCO (NCT04330690)
- Testing
- Artesunate, Imatinib, Infliximab
- Where
- 53 sites in Canada
- Volunteers
- 2,900 people
- Sponsor
- Sunnybrook Health Sciences Centre
COVID19
Trial to Study the Benefit of Colchicine in Patients With COVID-19
COVID-19 is associated with a cytokine storm that leads to respiratory distress, multiorgan failure and elevated mortality. Oral colchicine exhibits high anti-inflammatory capacity attributed to the inhibition of microtubules…
- Trial name
- COL-COVID (NCT04350320)
- Testing
- Colchicine Tablets, Standard therapy for COVID-19 according to the stablished hospital protocols.
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Fibromyalgia, Coronavirus Disease 2019 Pandemic
Anxiety, Depression, and Quality of Life in Patients With Fibromyalgia During the Coronavirus Disease 2019 Pandemic
Fibromyalgia patients and controls living in the same household will be evaluated for levels of resilience, covid-19 related anxiety, coronavirus disease 2019 related obsession, quality of life and pain and comparisons and…
- Trial name
- NCT05410808
- Testing
- Questionnaires and physical examination, Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ege University
Long COVID-19 Syndrome, Long COVID Symptoms
Epigenetic Changes in Long COVID Patients
The goal of this observational study is to improve the understanding of the biological mechanisms underlying long COVID and to identify molecular biomarkers that may support its diagnosis, prognosis, and future precision medicine…
- Trial name
- ECLIPSE (NCT07757620)
- Where
- 3 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
COVID-19, Liver Cirrhosis
COVID-19 in Patients With Pre-existing Cirrhosis (COVID-Cirrhosis-CHESS2002): A Multicentre Observational Study
COVID-19 pandemic with SARS-CoV-2 infection has become a global challenge. Though most cases of COVID-19 are mild, the disease can also be fatal.
- Trial name
- NCT04329559
- Where
- 15 sites in China
- Volunteers
- 21 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
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