Clinical trials: COVID19 Patients
Covid19
Dose-Finding, Safety, and Efficacy Study of XVR011 Added to Standard of Care in Patients Hospitalised for COVID-19
This is a 2 part study where the first part (Phase 1) evaluates the safety of XVR011 and aims to identify the recommended Phase 2 dose.
- Trial name
- NCT04884295
- Testing
- XVR011
- Where
- 6 sites in Belgium, Italy and 1 more
- Volunteers
- 27 people
- Sponsor
- ExeVir Bio BV
SARS-CoV-2
Trial of Inhaled Anti-viral (SNG001) for SARS-CoV-2 (COVID-19) Infection
SNG001 is an inhaled drug that contains a antiviral protein called interferon beta (IFN-β). IFN-β in produced in the lungs during viral lung infections.
- Trial name
- NCT04385095
- Testing
- SNG001
- Where
- 13 sites in United Kingdom
- Volunteers
- 221 people
- Sponsor
- Synairgen Research Ltd.
COVID-19, ARDS
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC vs. Placebo + SOC in Adult Hospitalized Patients With COVID-19
COVID-19 patients who develop severe disease often develop acute respiratory distress syndrome (ARDS) as a result of a dysregulated immune response.
- Trial name
- NCT04401475
- Testing
- SOC plus 15mg/kg EB05 IV
- Where
- 20 sites in United States, Canada
- Volunteers
- 278 people
- Sponsor
- Edesa Biotech Inc.
CLL, Multiple Myeloma
The Capability of Haemato-oncology Patients to Generate Antibodies Against COVID-19
The corona pandemic is a continuing global challenge due to Corona Virus 2019 (COVID-19). The purpose of the study is to evaluate the capability of Haemato-oncology patients to generate antibodies against COVID-19 after infection…
- Conditions
- CLL, Multiple Myeloma, Lymphoma
- Trial name
- NCT04746092
- Where
- Israel
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Satisfaction, Patient, Covid19
Virtual White Boards for Patient Satisfaction
Communication with patients on their clinical status is important in delivering care in the emergency department. During times of high volume or complex patients, there may be lapses in communicating with patients about their…
- Conditions
- Satisfaction, Patient, Covid19, Emergencies, Satisfaction
- Trial name
- NCT04497922
- Testing
- e-ink screen, Treatment as usual
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
COVID-19
Portable Oxygen Concentrator (POC) Versus Standard of Care in Long-COVID: Randomized Crossover Exploratory Pilot Study.
A prospective, open label, randomized, crossover, pilot, exploratory study to describe the effect of the Inogen One® G4 POC on brain hypoxia, peripheral oxygen saturation and cognitive function in adults with longterm- COVID.
- Trial name
- RESTORE (NCT05212831)
- Testing
- Inogen One® G4
- Where
- 2 sites in Canada
- Volunteers
- 21 people
- Sponsor
- Inogen Inc.
Covid19, Critically Ill
Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit
Studying clinical characterization of critically ill COVID-19 patients in a single center Studying Risk factors for Day 28 Mortality in COVID-19 patients admitted to intensive care unit
- Trial name
- ICUCOVID-KK (NCT04805645)
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Post Acute COVID-19 Syndrome
Gender Differences in the Recovery Rate Following PR in Patients With Long COVID-19
The goal of this retrospective analysis is to compare the magnitude of improvement in respiratory and peripheral muscle strength, following the completion of a hybrid pulmonary rehabilitation programme, in men and women with long…
- Trial name
- NCT05736939
- Testing
- Out-patient Pulmonary Rehabilitation
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- National and Kapodistrian University of Athens
Covid19, Acute Cardiovascular Disease
Russian Cardiovascular Registry of COVID-19
This is a Russian multicenter observational study aimed to assess the mid-term and long-term prognosis in patients recovered from COVID-19 with the involvement of the cardiovascular system or with baseline severe cardiovascular…
- Conditions
- Covid19, Acute Cardiovascular Disease, Cardiovascular Diseases
- Trial name
- NCT04724707
- Where
- Russia
- Volunteers
- 900 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Long COVID
A Study to Assess Anktiva in Patients With Long Covid-19.
This study will test the safety and tolerability of Anktiva in patients with Long Covid. Eligible patients will receive up to 2 doses of Anktiva and have follow-up exams and tests.
- Trial name
- INTERRUPT_LC (NCT07108036)
- Testing
- N-803 (IL-15 Superagonist)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ImmunityBio, Inc.
Olfaction Disorders, COVID-19
Morphological Abnormalities of the Olfactory Bulb on MRI and Olfactometry in Anosmic Versus Normosmic COVID-19 Patients
Olfactory and gustatory disorders are prevalent symptoms in European COVID-19 patients. This study aimed to detect these disturbances among positive COVID-19 patients (symptom not initially highlighted by the patient and not…
- Trial name
- NCT04526054
- Testing
- ENT exam, Olfactometry, Brain MRI
- Where
- 2 sites in France
- Volunteers
- 13 people
- Sponsor
- Hopital Foch
Covid19, Lymphopenia
Nicotinamide-based Supportive Therapy in Lymphopenia for Patients With COVID-19
The mechanism of peripheral blood lymphocyte decline in COVID-19 patients is not yet clear. However, one theory demonstrated that in the whole progression of COVID-19, the extensive activation of poly-ADP-ribose polymerase (PARP)…
- Trial name
- NCT04910230
- Testing
- nicotinamide
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Qiang Hu
Viral Pneumonia, COVID-19 Pneumonia
Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19
This is a Pilot study for evaluating the feasibility, security and efficacy of the use of Cypropheptadine, an antihistaminic and antiserotonin drug, as an adjunct of the standardized treatment in a population of patient who are…
- Conditions
- Viral Pneumonia, COVID-19 Pneumonia, Serotonin Syndrome, Platelet Dysfunction
- Trial name
- NCT04876573
- Testing
- Cyproheptadine Hydrochloride 4 MG
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
The Impact of COVID19 on Psoriasis Patients
Impact of COVID 19 on Psoriasis Patients
The main objective of this work is to investigate the effect of COVID-19 pandemic on psoriasis patients. This work is designed as a cross-sectional survey based on a questionnaire directed to Egyptian psoriasis patients.
- Trial name
- NCT05381402
- Testing
- Questionnaire
- Volunteers
- 230 people
- Sponsor
- Cairo University
COVID-19, Endothelial Function
Non-invasive Characterization of Systemic Microvascular Reactivity by Near-infrared Diffuse Optical Spectroscopy in COVID-19 Patients
The purpose of this study is to characterize microvascular reactivity on the forearm muscle using non-invasive near-infrared spectroscopy in critically ill COVID-19 patients, and to correlate its alterations with 28-day mortality…
- Trial name
- HEMOCOVID19 (NCT04689477)
- Testing
- Vascular occlusion test
- Where
- 8 sites in United States, Brazil and 2 more
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Covid19, Corona Virus Infection
Therapeutic Study to Evaluate the Safety and Efficacy of DW-MSC in COVID-19 Patients
This is a phase 1 clinical trial to verify the safety and efficacy of DW-MSC in COVID-19 patients. A total of 9 subjects are randomly allocated.
- Conditions
- Covid19, Corona Virus Infection, SAR
- Trial name
- DW-MSC (NCT04535856)
- Testing
- allogeneic mesenchymal stem cell
- Where
- Indonesia
- Volunteers
- 9 people
- Sponsor
- Ina-Respond
COVID-19, End Stage Renal Disease
The Danish Pre-HCQ COVID Dialysis Study
Hydroxychloroquine has been shown to inhibit replication of SARS-CoV-2 in vitro. The presented multicenter parallel-group open-label randomized clinical trial aims to investigate the efficacy of prophylactic hydroxychloroquine on…
- Trial name
- NCT05110651
- Testing
- Hydroxychloroquine
- Where
- 3 sites in Denmark
- Sponsor
- Nicholas Carlson
Rehabilitation
Implementing a Rehabilitation Program in Patients Recovering From Covid-19 Infection
Implementation of a supervised rehabilitation program in patients recovering from COVID-19-infection who suffer from limitations and symptoms due to the disease 6 to 8 weeks from hospital discharge.
- Trial name
- NCT04935437
- Testing
- Supervised rehabilitation program.
- Where
- Greece
- Volunteers
- 55 people
- Sponsor
- Evangelismos Hospital
COVID, Corona Virus Infection
Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19
COVID-19 patients with a severely symptomatic progression with development of an Acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 need prolonged intensive care treatment involving pharmacological immobilization…
- Conditions
- COVID, Corona Virus Infection, Sars-CoV2
- Trial name
- NCT04397172
- Testing
- Study Arm
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
COVID-19
Efficacy and Safety of Hydroxychloroquine and Azithromycin for Patients With Moderate to Severe COVID-19
This is an exploratory study to evaluate the efficacy of hydroxychloroquine (400 mg BID on D1 and 400 mg/day on D2 to D5) and azithromycin (500 mg/ 5 days) to treat moderate to severe COVID-19 pneumonia.
- Trial name
- NCT04329572
- Testing
- Hydroxychloroquine Sulfate, Azithromycin Tablets
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Azidus Brasil
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