Clinical trials: COVID19 Patients
COVID-19 Infection
UDCA in the Treatment of COVID-19 Infection and Its Clinical Prognosis in Patients With Autoimmune Liver Disease
This is a two-way (retrospective+prospective) cohort study of patients with primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) infected with COVID-19.
- Trial name
- NCT05812612
- Testing
- ursodeoxycholic acid
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Ditan Hospital
Covid19
Observational, Retrospective Study to Evaluate Coagulation Changes and the Influence of Antithrombin III Treatment in Patients With Severe COVID-19 Infection
Multicentre, multinational, non-interventional, observational, retrospective, patient record study to evaluate changes in coagulation parameters in patients with severe COVID-19 infection receiving/not treatment with antithrombin…
- Trial name
- NCT04651400
- Testing
- Antithrombin III
- Where
- 6 sites in Austria, France and 2 more
- Volunteers
- 300 people
- Sponsor
- Octapharma
COVID-19
Epidemiological Observation From a Smartphone Self-monitoring Application for Suspected COVID-19 Patients' Triage
A coronavirus pandemic began on 12/31/2020 with the first Chinese patient. As of 3/16/2020, the epidemic affects more than 100 countries with 169,000 official infections and 6,500 deaths.
- Trial name
- COVID CALL 15 (NCT04331171)
- Testing
- Web application users
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Weprom
COVID-19, Venous Thromboembolism
Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial
The researchers wanted to learn how to help sick patients who are in the hospital because of COVID-19. They are trying to find out the best way that is safe to stop blood clots that could be dangerous from forming in patients…
- Conditions
- COVID-19, Venous Thromboembolism, Arterial Thrombosis
- Trial name
- COVID-PACT (NCT04409834)
- Testing
- Unfractionated Heparin IV, Enoxaparin 1 mg/kg, Clopidogrel
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- The TIMI Study Group
Chronic Lymphocytic Leukemia, Indolent B-Cell Non-Hodgkin Lymphoma
Incidence of Severe COVID-19 Infection in Patients With CLL or B-NHL Who Received Pre-exposure Prophylaxis With Tixagevimab and Cilgavimab in Italy.
This is an observational retrospective and prospective multicenter study aimed at describing the role of the COVID -19 prophylaxis with Tixagevimab and Cilgavimab in CLL or indolent B-NHL patients who received first COVID-19…
- Conditions
- Chronic Lymphocytic Leukemia, Indolent B-Cell Non-Hodgkin Lymphoma, COVID-19
- Trial name
- NCT05803395
- Where
- 15 sites in Italy
- Volunteers
- 954 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Coronavirus Disease 2019 (COVID-19), SARS-CoV-2
Immunophenotyping Assessment in a COVID-19 Cohort
This surveillance study will collect detailed clinical, laboratory, and radiographic data in coordination with biologic sampling of blood and respiratory secretions and viral shedding in nasal secretions in order to identify…
- Trial name
- IMPACC (NCT04378777)
- Testing
- Biological sample collection, Data Collection: Clinical Care Assessments
- Where
- 17 sites in United States
- Volunteers
- 1,227 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid-19
Association of the Neutrophil/Lymphocyte Ratio With Clinical Complications and Mortality in COVID-19 Patients
There is little information about the clinical characteristics and risk factors of Covid-19 in Latin American countries considering the ethnic differences and the high prevalence of obesity and cardiometabolic diseases.
- Trial name
- NCT04434157
- Where
- Mexico
- Volunteers
- 221 people
- Sponsor
- Hospital Regional de Alta especialidad de Ixtapaluca
Corona Virus Infection, SARS-CoV 2
Convalescent Plasma for Treatment of COVID-19 Patients With Pneumonia
This is a single arm phase II trial to assess efficacy and confirm safety of infusions of anti-SARS-CoV-2 convalescent plasma in hospitalized patients with acute respiratory symptoms,with or without confirmed interstitial…
- Conditions
- Corona Virus Infection, SARS-CoV 2, SARS Pneumonia, Pneumonia
- Trial name
- NCT04374565
- Testing
- High-Titer Anti-SARS-CoV-2 (COVID 19) Convalescent Plasma
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Virginia
COVID-19
COVID-19 - Cytokine Storm
This is a multi-center study comparing clinical outcomes in patients with COVID-19 in subjects hospitalized at Hadassah and other hospitals for PCR or serology confirmed COVID-19 and compare the outcomes to the presence of…
- Trial name
- NCT04474067
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Covid19, Ards
Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure
The aim of this observational study is to evaluate the physiological and clinical effects of prone position in awake patients with respiratory failure due to COVID-19.
- Conditions
- Covid19, Ards, Respiratory Failure
- Trial name
- NCT04641182
- Testing
- Prone position
- Where
- Chile
- Volunteers
- 66 people
- Sponsor
- Pontificia Universidad Catolica de Chile
COVID-19 Respiratory Infection
Cardiovascular Disease and Outcomes Among Patients With SARS-CoV-2 Infection (COVID-19)
The coronavirus disease of 2019 (COVID-19) has affected over 2.4 million individuals worldwide and has resulted in >171,000 deaths. Cardiovascular disease (CVD) is an important contributor to death in these patients.
- Trial name
- NCT05085262
- Testing
- Bloodwork, Echocardiogram, PET/MRI, Bloodwork, Echocardiogram, MRI
- Where
- Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Secondary Bacterial Infection in COVID-19 Patients
Aerosolized Versus Intravenous Colistin-based Antimicrobial Regimens in Hospitalized COVID-19 Patients With Bacterial Coinfection: A Randomized Controlled Trial
Secondary bacterial pathogen infection has been demonstrated to aggravate COVID-19 clinical outcomes. Bacterial infections acquired during a hospital stay are likely resistant to several antimicrobial medicines, making COVID-19…
- Trial name
- colistin (NCT05689229)
- Testing
- Colistin
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Beni-Suef University
Pneumonia, Viral, Corona Virus Infection
Convalescent Antibodies Infusion in COVID 19 Patients
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, has become a major concern all over the world.
- Trial name
- NCT04418531
- Testing
- Anti-coronavirus antibodies (immunoglobulins) obtained with DFPP form convalescent patients
- Sponsor
- Piero Luigi Ruggenenti
Covid19
Impact of Previous Treatment of HCV Patients by DAADs on Covid-19 Disease Frequency and Severity
Evaluate effect of DAADs on covid-19 disease.
- Trial name
- NCT04729153
- Testing
- DAAD Compound
- Volunteers
- 100 people
- Sponsor
- Assiut University
Covid19
ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19
This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure.
- Trial name
- TESICO (NCT04843761)
- Testing
- Remdesivir, Aviptadil, Corticosteroid
- Where
- 40 sites in United States
- Volunteers
- 473 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Phosphate Deficiency, Covid19
The Effect of COVID-19 Patients' Serum Phosphate Level on Mortality in ICU
The investigators aimed to investigate the relationship between phosphate level and mortality using the 4C Mortality Score in COVID-19 patients who were followed up in the intensive care unit.
- Conditions
- Phosphate Deficiency, Covid19, Mortality
- Trial name
- NCT04800770
- Testing
- 4C mortality score
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Covid19
Evaluation of Sofosbuvir and Daclatasvir Combo in COIVD-19 Patients in Egypt
Sofosbuvir has been recently recommended as a possible antiviral for COVID-19, based on structural studies and multiple alignment analysis.
- Trial name
- NCT04773756
- Testing
- Sofosbuvir 400 MG/ Daclatasvir 60mg
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Alexandria University
COVID-19 Confirmed Cases, COVID-19 Mortality
COVID - AirPollution
Epidemiological data have related particulate matter (PM), nitrogen dioxide (NO2) and ozone (O3) to COVID-19 morbidity and mortality at the population level.
- Trial name
- NCT04463862
- Where
- 8 sites in Belgium, France
- Volunteers
- 660 people
- Sponsor
- University Hospital, Strasbourg, France
Cognitive Impairment, COVID-19 Respiratory Infection
Cognitive Impact in Patients With COVID-19 Infection
SARS-COV-2 (severe acute respiratory syndrome- corona virus - 2) infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered.
- Trial name
- NCT05293561
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Covid-19 With Positive RT-PCR
Incidence of Acute Pulmonary Embolism in Covid-19 Patients on CT Angiography and Relationship to D-dimer Levels
Reports of acute pulmonary embolism (APE) associated with COVID-19 have emerged in the literature. For example, Chen et al. described 25 pulmonary CT angiograms examinations from 1008 COVID-19 patients; 10 were positive for…
- Trial name
- COVID-APE (NCT04373486)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Strasbourg, France
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