Clinical trials: COVID19 Patients
Severe Acute Respiratory Syndrome (ARDS) Secondary to SARS-COV-2 Infection
An Observational Study of the Use of Siltuximab (SYLVANT) in Patients Diagnosed With COVID-19 Infection Who Have Developed Serious Respiratory Complications
This observational study will collect data from patients treated with siltuximab program for treatment of SARS-CoV-2 infection complicated with serious respiratory complications.
- Trial name
- SISCO (NCT04322188)
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Sars-CoV-2 Infection
Immune Response to Third Dose of SARS-CoV-2 Vaccine in a Cohort of Cancer Patients on Active Treatment
The Coronavirus Disease 2019 (COVID-19) pandemic has claimed over 5 million lives globally. Fortunately, a substantial and growing number of SARS-CoV-2 vaccines with very high efficacy have been developed, manufactured, and…
- Trial name
- NCT05119738
- Testing
- Three doses of BNT162b2 (observational), Two doses of Coronavac and one dose BNT162b2 (observational)
- Where
- Chile
- Volunteers
- 122 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Motor Neuropathy, Sensory Neuropathy
Short-term Evaluation of Motor and Sensory Function in Post-COVID-19 Patients
SARS-COV-2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. our aim is to evaluate neurological impact of covid-19; if there is any.
- Trial name
- NCT05721040
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
SARS Virus
IMATINIB IN COVID-19 DISEASE IN AGED PATIENTS.
High-throughput screening studies identified Abl kinase inhibitors (including imatinib) as inhibitors of coronaviruses SARS and MERS. The SARS-CoV-2 coronavirus depend on Abl2 kinase activity to fuse and enter into the cells.
- Trial name
- IMAGE-19 (NCT04357613)
- Testing
- Experimental drug
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Versailles Hospital
Covid-19
Evaluation of Clinical Parameters on Admission and Medications in Covid-19 Pneumonia (Corona Virus Disease 2019)
Investigators will recruit patients diagnosed with COVID-19 pneumonia between March 11th, 2020 and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics, retrospectively and analyze their clinical and…
- Trial name
- Covid-19 (NCT04379310)
- Testing
- ACE Inhibitors and Calcium Channel Blockers
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul Nisantasi University
Covid19, Maternal-Fetal Relations
Maternal And Neonatal Outcome of Pregnant Patients With COVID-19 in Istanbul, Turkey: A Single-Center, Retrospective, Descriptive Study
Evaluation of apgar, hemogram and developmental status of babies born from covid 19 positive mothers
- Trial name
- NCT04337320
- Testing
- newborns from covid 19 positive mothers
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Covid19
Charité Trial of Cenicriviroc (CVC) Treatment for COVID-19 Patients
The aim of this study is to test Cenicriviroc (CVC) as a means to reduce the severity of the lung disease COVID-19 caused by an infection with SARS-CoV-2.
- Trial name
- NCT04500418
- Testing
- Cenicriviroc (CVC)
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Charite University, Berlin, Germany
Acute Respiratory Distress Syndrome, Coronavirus
Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS).
This is a multicenter, randomized, double-blind, parallel group study to investigate the efficacy of pemziviptadil (PB1046) by improving the clinical outcomes in hospitalized COVID-19 patients at high risk for rapid clinical…
- Conditions
- Acute Respiratory Distress Syndrome, Coronavirus, Hypoxic Respiratory Failure, Hypoxemic Respiratory Failure
- Trial name
- VANGARD (NCT04433546)
- Testing
- Pemziviptadil (PB1046), Low Dose (10 mg) Control
- Where
- 4 sites in United States
- Volunteers
- 54 people
- Sponsor
- PhaseBio Pharmaceuticals Inc.
Covid19
Risk Factors Worsening COVID19 for Out-patient With Home Monitoring
The main objective of the COVIDADOMEVA study is to identify the risk factors aggravating the COVID-19 (risk or protective factors), in out-patients suspected of being infected with precocious home monitoring.
- Trial name
- COVIDADOMEVA (NCT04380662)
- Testing
- Risk factors
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Grenoble
COVID-19
A Specific miRNA Encoded by SARS-CoV-2 as a Diagnostic Tool to Predict Disease Severity in COVID-19 Patients
Coronavirus disease is caused by SARS-CoV-2, known as 2019 novel coronavirus (2019-nCoV). To date has caused a large number of deaths causing serious respiratory illness such as pneumonia and lung failure, therefore representing…
- Trial name
- CoV-miR (NCT05739513)
- Testing
- miRNA analysis in plasma
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
COVID-19 Pneumonia
Ivermectina Colombia (IVERCOL)
A parallel, prospective, double-blind, placebo-controlled clinical trial will be conducted in the population affiliated to EPS SURAMERICANA S.A. with positive test for antigen and PCR for SARS-CoV-2.
- Trial name
- IVERCOL (NCT04886362)
- Testing
- Ivermectin
- Volunteers
- 966 people
- Sponsor
- Ayudas Diagnosticas Sura S.A.S
Covid-19
A Study of N-acetylcysteine in Patients With COVID-19 Infection
The study researchers think that a medication called N-acetylcysteine can help fight the COVID-19 virus by boosting a type of cell in your immune system that attacks infections.
- Trial name
- NCT04374461
- Testing
- N-acetylcysteine, Peripheral Blood
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Covid-19, Hypoxia
Hydrocortisone for COVID-19 and Severe Hypoxia
We aim to assess the benefits and harms of low-dose hydrocortisone in patients with COVID-19 and severe hypoxia.
- Trial name
- COVID STEROID (NCT04348305)
- Testing
- Hydrocortisone, Sodium Chloride 9mg/mL
- Where
- 14 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Scandinavian Critical Care Trials Group
COVID-19 Vaccine
Efficacy and Safety of Covid-19 Vaccine in Cardiac Patients
Efficacy and safety of covid-19 vaccine in Cardiac patients
- Trial name
- NCT05348629
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Mina sobhi said fam
Covid19
Organization of Pulmonary Rehabilitation of Post-COVID-19 Patient With Sequelae (REHABCOVID)
Some patients with COVID-19 have sequelae after the acute phase of infection. These sequelae can be physical (dyspnea, exercise intolerance, abnormal fatigue) but also psychic (anxiety, depression).
- Trial name
- REHABCOVID (NCT04634318)
- Testing
- Respiratory rehabilitation program (RR)., Respiratory tele-rehabilitation program (TRR).
- Where
- 3 sites in France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Covid19
Hyperbaric Oxygen for Long COVID-19 Pulmonary Sequela
This is a pilot study in 24 subjects where half will be randomized to 10 treatments with hyperbaric oxygen (HBO). It will primarily study pulmonary sequelae with imaging and physiological measurements (low dose chest computer…
- Trial name
- NCT04905888
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Sponsor
- Peter Lindholm
COVID, Respiratory Distress Syndrome
BAttLe Against COVID-19 Using MesenchYmal Stromal Cells
The investigational medicinal product consists of expanded allogeneic mesenchymal stromal cells derived from adipose tissue and administered intravenously.
- Trial name
- NCT04348461
- Testing
- Allogeneic and expanded adipose tissue-derived mesenchymal stromal cells
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Inflammatory Disease, Covid19
Evaluation of the Impact of Lock Down and End of Lock Down on the Management of Patients With Inflammatory and Dysimmune Diseases Followed in the Context of IMMINeNT FHU and COVID-19
This questionnaire is distributed via a mailing list (e-mail) of patients treated within the framework of the FHU for pathologies including chronic inflammatory bowel diseases or IBD (Crohn's disease and ulcerative colitis)…
- Trial name
- CONFIMID (NCT04513561)
- Where
- France
- Volunteers
- 921 people
- Sponsor
- University Hospital, Lille
COVID-19
COVID-19 Convalescent Plasma (CCP) Transfusion
This research study evaluates the safety and effectiveness for the use of convalescent plasma transfusion as a treatment option for novel coronavirus SARS-CoV-2 infection (COVID-19).
- Trial name
- NCT04412486
- Testing
- COVID Convalescent Plasma
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Gailen D. Marshall Jr., MD PhD
Coronavirus Infections
COVID-19 Patients Characterization, Biobank, Treatment Response and Outcome Predictor
Collection and analysis of demographic, clinical, radiographic and laboratory characteristics of CoViD-19 patients to identify predictors of disease severity, mortality and treatment response, and to identify subgroup of patients…
- Trial name
- COVID-BioB (NCT04318366)
- Testing
- Observational Study
- Where
- 13 sites in Italy
- Volunteers
- 6,000 people
- Sponsor
- Università Vita-Salute San Raffaele
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