Clinical trials: COVID19 Patients
Sars-CoV2, Symptomatic Condition
PRophylaxis of Exposed COVID-19 Individuals With Mild Symptoms Using choloroquinE Compounds
To treat Pakistani patients with non-life threatening symptomatic SARS-CoV-2 infection with an intent to reduce burden on institutional healthcare services by determining efficacy of different chloroquine and hydroxychloroquine…
- Conditions
- Sars-CoV2, Symptomatic Condition, Covid-19
- Trial name
- PRECISE (NCT04351191)
- Testing
- Hydroxychloroquine Sulfate Regular dose, Hydroxychloroquine Sulfate Loading Dose, Chloroquine
- Where
- 4 sites in Pakistan
- Volunteers
- 137 people
- Sponsor
- Government of Punjab, Specialized Healthcare and Medical Education Department
COVID-19
Validation of Prognostic Clinical Risk Scores in Predicting Outcome for Patients With COVID-19 at Initial Triage
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing Covid-19 pandemic continues to be a global health threat with a massive burden on health care systems resulting in more than six million deaths in…
- Trial name
- NCT05582382
- Testing
- logistic regression of known prognostic markers of severity of COVID19
- Where
- United Arab Emirates
- Volunteers
- 2,000 people
- Sponsor
- Dr Adnan Agha
COVID 19
Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19
Nasal saline irrigations are a safe and commonly used mechanism to treat a variety of sinonasal diseases including sinusitis, rhinitis, and upper respiratory tract infections.
- Trial name
- NCT04347538
- Testing
- Saline Nasal Irrigation
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Vanderbilt University Medical Center
Covid19, ME/CFS
Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)
The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently tested adults, both negative and positive, who have…
- Conditions
- Covid19, ME/CFS, SARS COV2, Novel Coronavirus Infection
- Trial name
- INSPIRE (NCT04610515)
- Where
- 8 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- Rush University Medical Center
End Stage Kidney Disease, Kidney Transplantion
The Response of the Immune System of Patients With End Stage Kidney Disease on Dialysis and Kidney Transplant Recipients Vaccinated for COVID-19
Observational study of patients with End Stage Kidney Disease on dialysis and Kidney Transplant Recipients, before and after vaccination for SARS-COV 2, after written consent, with the aim of laboratory efficacy of the vaccine…
- Conditions
- End Stage Kidney Disease, Kidney Transplantion, Covid19, Vaccination
- Trial name
- NCT04932876
- Testing
- SARS - COV 2 VACCINE
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Ioannina
SARS-CoV-2 (COVID-19) Severe Pneumonia
Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19
To evaluate the safety and preliminary efficacy of efzofitimod, compared to placebo matched to efzofitimod, in hospitalized participants with SARS-CoV-2 (COVID-19) severe pneumonia not requiring mechanical ventilation.
- Trial name
- NCT04412668
- Testing
- Efzofitimod 1 mg/kg, Efzofitimod 3 mg/kg
- Where
- 10 sites in United States, Puerto Rico
- Volunteers
- 36 people
- Sponsor
- aTyr Pharma, Inc.
COVID-19, Hemostasis
Thrombo Embolic Events in Hospitalized Patients With Covid-19 Serious Acute Pneumopathy
The understanding of haemostasis and inflammation cross-talk has gained considerable knowledge during the past decade in the field of arterial and venous thrombosis.
- Conditions
- COVID-19, Hemostasis, Coagulation
- Trial name
- THROMBCOVID2 (NCT04377490)
- Testing
- venous ultrasound, blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Covid19, Emergencies
Prediction of the Patient Pathway in Emergency Room in an Exceptional Sanitary Situation
The COVID-19 outbreak leads to optimize the pathway in emergency departments. The length of time spent in the Emergency Department is linked to the morbi-mortality and the risk of COVID-19 transmission.
- Trial name
- 3PU-SSE (NCT04665778)
- Testing
- hospital bedroom booking
- Where
- France
- Volunteers
- 1,516 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hyponatremia, Covid19
HYPONATREMIA IN COVID-19 PATIENTS
SYSTEMIC INFLAMMATION HAS BEEN ASSOCIATED WITH SEVERE COVID-19. HYPONATREMIA CAN RESULT FROM INFLAMMATION DUE TO NON-OSMOTIC STIMULI FOR VASOPRESSIN PRODUCTION.
- Conditions
- Hyponatremia, Covid19, Corona Virus Infection
- Trial name
- NCT04493268
- Where
- Argentina
- Volunteers
- 250 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
COVID-19
Emergency Ventilator Splitting Between Two or More Patients (COVID-19)
The purpose of this study is to develop a safe, easily scalable, and simple method to split a single ventilator for use amongst two or more patients, thus serving as a capacity bridge to save patient lives until manufacturers can…
- Trial name
- NCT04381013
- Testing
- Emergency Ventilator Splitter
- Where
- United States
- Sponsor
- Stanford University
Thrombosis, Covid-19
Thrombosis and Covid-19
The coronavirus disease of 2019 (COVID-19) is a viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), now deemed a pandemic by the World Health Organization.
- Conditions
- Thrombosis, Covid-19, SARS-CoV 2
- Trial name
- COVBIO (NCT04366778)
- Testing
- TEM-tPA
- Where
- France
- Volunteers
- 341 people
- Sponsor
- Hospices Civils de Lyon
COVID-19 Acute Respiratory Distress Syndrome
Positive End Espiratory Pressure Trial in Coronavirus Disease 19 Treated With Continuous Positive Airway Pressure
Consecutive patients with hypoxemic respiratory failure, CT evidence of bilateral pneumonia and diagnosis of Coronavirus Disease 19 (COVID-19) with molecular nasopharyngeal swab consecutively admitted to the COVID Care Unit of…
- Trial name
- NCT05178160
- Testing
- PEEP Standard Protocol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Santa Maria delle Grazie Hospital
Corona Virus Infection, Covid19
Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19
A preparation of CimertrA, comprising Artemisinin, Curcumin, and Boswellia, and Vitamin C in a nanoparticular formulation, is proposed as a treatment for the disease associated with the novel coronavirus SARS-CoV-2.
- Conditions
- Corona Virus Infection, Covid19, SARS-CoV Infection
- Trial name
- CimetrA (NCT04802382)
- Testing
- Confirm SARS-CoV-2 infection, Physical Examination, Vital Signs
- Where
- 2 sites in Israel
- Volunteers
- 252 people
- Sponsor
- MGC Pharmaceuticals d.o.o
COVID19 Pneumonia
Trial Evaluating Efficacy and Safety of Bevacizumab (Avastin®/Zeribev®) in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort
Bevacizumab, ZERIBEV® (Pfizer)/AVASTIN® (Roche) 25 mg/ml ®, is a recombinant humanised monoclonal IgG1 antibody It seems interesting to use bevacizumab in severe patients infected with SARS-CoV-2 requiring hospitalization in…
- Trial name
- CORIMMUNO-BEVA (NCT04344782)
- Testing
- Bevacizumab Injection
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID, Hypertension
Drug Safety and the Occurrence of Complications During Hospitalization in Patients With COVID-19
Hospitalized patients with COVID-19 will be included in the study in centers around Poland. After the hospitalization, a short questionnaire will be completed, including pre-hospitalization diagnoses, pre-hospitalization…
- Conditions
- COVID, Hypertension, Cardiovascular Diseases, Cardiovascular Risk Factor
- Trial name
- COR-CARDIO (NCT04374110)
- Testing
- Clinical data
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
COVID-19
CAPTION AI to Minimize Risk of COVID Exposure
Participants scheduled for for an echocardiogram (echo) and being evaluated for, or is positive for COVID-19 will be asked if they would be willing to have their echo done using a new software program on one of the hand-held…
- Trial name
- CAPTION AI (NCT04336774)
- Testing
- Caption AI
- Where
- 2 sites in United States
- Sponsor
- Duke University
COVID-19, Mental Health Impairment
A Study on a Digital Platform for COVID19+ Patients, Designed to Facilitate Communication and Mental-health Care During and After Hospitalization.
This study presents a digital mental-health protocol designed to offer remote, personalized support to former or current COVID-19 patients. A total of 100 subjects will be enrolled.
- Conditions
- COVID-19, Mental Health Impairment, Telemedicine
- Trial name
- DigiCOVID (NCT05231018)
- Testing
- Psychotherapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Covid19, SARS-CoV Infection
Tenofovir-DF Versus Hydroxychloroquine in the Treatment of Hospitalized Patients With COVID-19 (TEDHICOV)
Although several therapeutic agents have been suggested for the treatment of the disease caused by the Coronavirus of the year 2019 (COVID-19), no antiviral has yet demonstrated consistent efficacy.
- Conditions
- Covid19, SARS-CoV Infection, Tenofovir
- Trial name
- TEDHICOV (NCT04812496)
- Where
- Peru
- Volunteers
- 100 people
- Sponsor
- Hospital Nacional Carlos Alberto Seguin Escobedo - EsSalud
Parkinson Disease, Diabetes Mellitus
Health Indicators and Patient Reported Outcomes. Identification of Significative Items Aimed at Improving Health Care Procceses.
The objective of this study is to identify key indicators in the follow-up of subjects with different pathologies related to both the person's environment, as well as the perception of their health and general quality of life and…
- Conditions
- Parkinson Disease, Diabetes Mellitus, COVID-19, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- OUTCOMES (NCT05343962)
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Instituto de Biomecanica de Valencia
Post-COVID ME/CFS
Repeat Immunoadsorption Post Covid ME/CFS
The evidence for an autoimmune etiology in postinfectious myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is growing.
- Trial name
- NCT05629988
- Testing
- IA with TheraSorb ® column
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
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