Clinical trials: CPAP Treatment
Obstructive Sleep Apnea (OSA), CPAP
Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure
Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease.
- Conditions
- Obstructive Sleep Apnea (OSA), CPAP, Biomarkers for Prediction of OA Treatment Efficacy
- Trial name
- BIOSA (NCT07792746)
- Testing
- Continuous Positive Airway Pressure
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Millenaire
Analgesia
Analgesic Efficacy of Oral Glucose in Preterm Neonates During Suctioning
Nasopharyngeal suctioning is a painful procedure that often becomes necessary in the care of preterm infants under CPAP therapy several times a day.
- Trial name
- Glucose FG (NCT00761059)
- Testing
- Glucose 20%, Aqua
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Cologne
Obstructive Sleep Apnea, Hypertension
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
- Trial name
- HRV-OSA-HTN (NCT07603583)
- Testing
- Polysomnography
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
Obstructive Sleep Apnea
The Effect of Mandibular Advancement Devices on Markers of Cardiovascular Health in Obstructive Sleep Apnea Patients
Obstructive sleep apnea (OSA) is a type of disordered breathing defined by the repetitive obstruction of airflow during sleep due to upper airway collapse. Each obstructive event contributes to decreased blood oxygen, or hypoxia.
- Trial name
- NCT05387122
- Testing
- mandibular advancement device (MAD)
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Alberta
Non-alcoholic Fatty Liver Disease
Evaluating the Efficacy of CPAP Therapy for the Treatment of Fatty Liver
We are doing this research study to evaluate whether continuous positive airway pressure (CPAP), a treatment for sleep apnea, will also help treat fatty liver disease.
- Trial name
- NCT01849081
- Testing
- CPAP, LIfestyle
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Aherence, Physical Symptoms
The Effectiveness of Augmented Reality to Enhance CPAP Therapy in OSA Patients
The goal of this clinical trial is to exam if artificial reality works to improve continuous positive airway pressure (CPAP) adherence in obstructive sleep apnea (OSA) patients.
- Conditions
- Aherence, Physical Symptoms, Mental Health, Quality of Life
- Trial name
- CPAP OSA (NCT06520592)
- Testing
- With AR guided CPAP therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Sleep Apnea, Obstructive, Bariatric Surgery
Effect of CPAP Versus APAP in Patients With Obesity Undergoing Bariatric Surgery Protocol
Introduction Obstructive sleep apnea (OSA) is a common disorder in obese patients, especially those undergoing bariatric surgery.
- Conditions
- Sleep Apnea, Obstructive, Bariatric Surgery, Obesity, Treatment Adherence and Compliance
- Trial name
- ObesAOS (NCT07001215)
- Testing
- In the intervention group, patients will be treated with auto-adjusting APAP, providing variable pressures throughout the sleep hours., CPAP
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Universitario Ramon y Cajal
CALR Gene Mutation, Essential Thrombocythemia
CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia
This early phase I trial studies how well the use of a continuous positive airway pressure (CPAP) machine works in treating obstructive sleep apnea in patients with polycythemia vera or essential thrombocythemia.
- Conditions
- CALR Gene Mutation, Essential Thrombocythemia, JAK2 Gene Mutation, MPL Gene Mutation
- Trial name
- NCT03972943
- Testing
- Continuous Positive Airway Pressure, Patient Observation, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Nasal Continuous Positive Airway Pressure,, Preterm Infants,
Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
We hypothesis a period of early NCPAP before surfactant treatment is effective for treating RDS and preventing BPD in very premature infants.
- Conditions
- Nasal Continuous Positive Airway Pressure,, Preterm Infants,, Surfactant Treatment,, Respiratory Distress Syndrome,
- Trial name
- NCT01996670
- Volunteers
- 683 people
- Sponsor
- Xiangya Hospital of Central South University
Obstructive Sleep Apnea Syndrome
Telemedicine to Enhance Adherence to CPAP Therapy in Patients With OSAS
We hypothesize that the use of telemedicine combined with support interventions by short messages, telephone calls and ambulatory visits to control CPAP treatment during the first month improves adherence and reduces unresolved…
- Trial name
- NCT01715194
- Testing
- Telemedicine intervention
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Otto D. Schoch
Obstructive Sleep Apnea
Brain Fog in Sleep Apnea
Objective: This observational, cross-sectional pilot study aims to assess "Brain Fog" (cognitive symptoms impacting memory, attention, and concentration) in severe Obstructive Sleep Apnea (OSA) patients.
- Trial name
- BF -OSA (NCT06664450)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Mild Obstructive Sleep Apnea Syndrome
Continuous Positive Airway Pressure and Oral Appliances Treatments in Mild Obstructive Sleep Apnea
Treatment response of mild obstructive sleep apnea (OSA) to continuous positive airway pressure (CPAP) therapy and oral appliance (OA) is still controversial.
- Trial name
- OSAS (NCT01461486)
- Testing
- Continuous Positive Airway Pressure (CPAP), Oral Appliance (BRD)
- Where
- Brazil
- Volunteers
- 79 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Obstructive Sleep Apnea, Stroke
Sleep Apnea Treatment After Stroke (SATS)
The purpose of this study is to determine if treating stroke patients who have obstructive sleep apnea with continuous positive airway pressure will improve symptoms caused by the stroke.
- Trial name
- NCT00282815
- Testing
- continuous positive airway pressure or CPAP
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea Syndrome
Air Leakage Under Continuous Positive Airway Pressure
The software embedded in recent continuous positive pressure devices enables the analysis of the level of leakage that occurs during treatment around the mask or from the mouth.
- Trial name
- SAS-leak-1 (NCT03381508)
- Testing
- Brizzy continuous positive pressure device
- Where
- 3 sites in France
- Volunteers
- 79 people
- Sponsor
- University Hospital, Montpellier
Fibromyalgia, Primary
Obstructive Sleep Apnea Syndrome and Fibromiyalgia
-------------Obstructive sleep apnea syndrome (OSAS) is a syndrome characterized by recurrent complete (apnea) or partial (hypopnea) upper respiratory tract obstruction episodes during sleep and a decrease in blood oxygen…
- Trial name
- NCT06595771
- Testing
- continuous positive airway pressure, Polysomnography
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Hypertension, Cardiac Function and Hemodynamics
AKTIIA OBPM to Assess CPAP Effect on Blood Pressure in Obstructive Sleep Apnea
The goal of this clinical trial is to learn if positive airway pressure (CPAP) therapy works for blood pressure (BP) control in obstructive sleep apnea (OSA) adult patients plus undiagnosed hypertension (HBP), using a cuffless…
- Conditions
- Hypertension, Cardiac Function and Hemodynamics, Usability, Patient Experience
- Trial name
- AVLA1 (NCT06446934)
- Testing
- CPAP
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario Araba
Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea
Empirical CPAP Therapy for Suspected Obstructive Sleep Apnea in a Resource-Limited Setting
Obstructive sleep apnea (OSA) is a condition where a person's airway repeatedly collapses during sleep, causing them to stop breathing briefly and disrupting their rest.
- Conditions
- Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea, Sleep Apnea Syndromes
- Trial name
- NCT07693101
- Volunteers
- 80 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea, CPAP Treatment
OurSleepKit To Support CPAP Adherence
The goal of this clinical trial is to learn if a couple-focused mobile health intervention will improve the use of continuous positive airway pressure (CPAP), the primary treatment option for obstructive sleep apnea (OSA).
- Conditions
- Obstructive Sleep Apnea, CPAP Treatment, Treatment Adherence
- Trial name
- NCT06621511
- Testing
- OurSleepKit
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Sleep Apnea
Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment
Obstructive sleep apnea (OSA) is a highly prevalent condition in hypertensive patients. The renin-angiotension-aldosterone-system (RAAS) has a central role in blood pressure control.
- Trial name
- LosartanPAP (NCT00701428)
- Testing
- Losartan, CPAP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Skaraborg Hospital
Obstructive Sleep Apnea Syndrome
Feasibility Evaluation of CPAP in the Treatment of Obstructive Sleep Apnea Synchrone in the Acute Phase of Stroke
This project is focused on the treatment of obstructive sleep apnea in the acute phase of stroke. Stroke is a frequent pathology with a high morbidity and mortality rate.
- Trial name
- NCT02522819
- Testing
- CPAP
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne