Clinical trials: CPPD - Calcium Pyrophosphate Deposition Disease
Chondrocalcinosis
Diagnostic Rentability of Screening for Associated Conditions in Calcium Pyrophosphate Deposition Disease Patients
The purpose of this study is to determine whether thorough analytical evaluation is useful to diagnose metabolic conditions associated to calcium pyrophosphate deposition disease.
- Trial name
- NCT00453128
- Where
- Spain
- Volunteers
- 240 people
- Sponsor
- Sociedade Galega de Reumatoloxía
Calcium Pyrophosphate Deposition Disease
Effect of Probenecid on Synovial Fluid ATP Levels in CPPD
This study will investigate the hypothesis that probenecid, a medication currently used for gout, reduces levels of ATP in the joint fluid of patients with calcium pyrophosphate deposition disease (CPPD), another common type of…
- Trial name
- NCT02243631
- Testing
- Probenecid
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- VA Office of Research and Development
Chondrocalcinosis
Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD Arthritis
Chondrocalcinosis, recently renamed the calcium pyrophosphate deposition (CPPD) disease, is a very frequent affection of the elderly and causes very painful arthritis.
- Trial name
- COLCHICORT (NCT03128905)
- Testing
- Colchicine opocalcium 1mg, Prednisone : Cortancyl 20mg
- Where
- 7 sites in France
- Volunteers
- 111 people
- Sponsor
- Lille Catholic University
Calcium Pyrophosphate Deposition Disease, Chondrocalcinosis
Baricitinib in CPPD - the BAPTIST Study
The aim of this clinical trial is to determine if baricitinib is effective in treating calcium pyrophosphate deposition disease (CPPD) in adults. The primary objective is to assess its impact on joint inflammation.
- Trial name
- BAPTIST (NCT06768294)
- Testing
- Baricitinib 4 MG Oral Tablet, Methylprednisolone (Corticosteroid), Colchicine 1 MG Oral Tablet
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Gitelman Syndrome, CPPD - Calcium Pyrophosphate Deposition Disease
The Osteoarticular Manifestations in Patients With Gitelman Syndrome
Patients with clinically and genetically confirmed Gitelman Syndrome are screened for CPPD, and the clinical and radiographic manifestations are collected and analyzed.
- Trial name
- CPPD and more (NCT06922370)
- Testing
- conventional radiograph or computed tomography
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Calcium Pyrophosphate Deposition Disease, Rheumatic Diseases
Calcium Pyrophosphate Deposition (CPPD) Disease
The goal of this clinical trial is to describe the transcriptomic and metabolomic profile of patients with chronic Calcium Pyrophosphate Deposition (CPPD) compared to those with acute CPPD.
- Trial name
- PYC-OMIC (NCT07005804)
- Testing
- transcriptomic and metabolomic analysis
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Lille Catholic University
CPPD - Calcium Pyrophosphate Deposition Disease
Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment
The goal of this clinical trial is to learn if colchicine reduces levels of proteins indicating inflammation in the blood in individuals with calcium pyrophosphate deposition (CPPD) disease.
- Trial name
- CRYSTALLIZE (NCT06855433)
- Testing
- Colchicine Pill
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Brigham and Women's Hospital
CPPD - Calcium Pyrophosphate Deposition Disease
Perspectives on CPPD Outcome Domains
The purpose of this study is to obtain patient and stakeholder perspectives on what outcome measures should be included in future trials on CPPD (Calcium PyroPhosphate Deposition), a common form of inflammatory arthritis.
- Trial name
- NCT04176003
- Testing
- Qualitative interview, Member checking
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
CPPD - Calcium Pyrophosphate Deposition Disease, Gout
The Orienting Study
This study at IRCCS Galeazzi - Sant'Ambrogio Hospital involves patients with gout, CPPD, and osteoarthritis as a control group. Patients will receive routine care with regular clinical, laboratory, and imaging assessments every…
- Trial name
- ORIENTING (NCT07504146)
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Calcium Pyrophosphate Deposition Disease
Tocilizumab in Chronic Inflammatory CPPD Disease
The aim of this clinical trial is to determine the efficacy of tocilizumab (an IL-6 inhibitor) in treatment-refractory chronic inflammatory forms of CPPD.
- Trial name
- TociCCAre (NCT07254637)
- Testing
- Tocilizumab
- Where
- 12 sites in France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris